BLM helicase facilitates telomere replication during leading strand synthesis of telomeres (Q28771475)

14 February 2017

title

BLM helicase facilitates telomere replication during leading strand synthesis of telomeres (English)

1 reference

Werner syndrome RecQ like helicase

14 February 2017

main subject

1 reference

Bloom syndrome, RecQ like helicase

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

William C. Drosopoulos

series ordinal

1

1 reference

14 February 2017

Settapong T. Kosiyatrakul

series ordinal

2

1 reference

14 February 2017

Carl L. Schildkraut

series ordinal

3

1 reference

14 February 2017

language of work or name

English

0 references

publication date

20 July 2015

1 reference

14 February 2017

published in

Journal of Cell Biology

1 reference

14 February 2017

volume

210

1 reference

14 February 2017

issue

2

1 reference

14 February 2017

page(s)

191–208

1 reference

Solution structure of a G-quadruplex bound to the bisquinolinium compound Phen-DC(3)

14 February 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Quantitative visualization of DNA G-quadruplex structures in human cells

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

RecQ helicases in DNA double strand break repair and telomere maintenance

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Purification of proteins associated with specific genomic Loci

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Replication fork velocities at adjacent replication origins are coordinately modified during DNA replication in human cells

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

The Werner and Bloom syndrome proteins catalyze regression of a model replication fork

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Quadruplex DNA: sequence, topology and structure

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Shelterin: the protein complex that shapes and safeguards human telomeres

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint.

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Telomere shortening exposes functions for the mouse Werner and Bloom syndrome genes

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Plasticity of DNA replication initiation in Epstein-Barr virus episomes

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Cancer predisposition caused by elevated mitotic recombination in Bloom mice

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Mutations in the WRN gene in mice accelerate mortality in a p53-null background

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Mammalian telomeres end in a large duplex loop

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Regulation of gene expression by the BLM helicase correlates with the presence of G-quadruplex DNA motifs.

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Human RecQ helicases in DNA repair, recombination, and replication.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Inhibition of DNA synthesis facilitates expansion of low-complexity repeats: is strand slippage stimulated by transient local depletion of specific dNTPs?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

The BLM helicase contributes to telomere maintenance through processing of late-replicating intermediate structures

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Human telomeres replicate using chromosome-specific, rather than universal, replication programs

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

G-quadruplex-induced instability during leading-strand replication

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

The Werner and Bloom syndrome proteins help resolve replication blockage by converting (regressed) holliday junctions to functional replication forks

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Genetic instability triggered by G-quadruplex interacting Phen-DC compounds in Saccharomyces cerevisiae

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Decreased replication origin activity in temporal transition regions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Telomeres do the (un)twist: helicase actions at chromosome termini

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Replication fork movement sets chromatin loop size and origin choice in mammalian cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Ligands playing musical chairs with G-quadruplex DNA: a rapid and simple displacement assay for identifying selective G-quadruplex binders

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Telomere ResQue and preservation--roles for the Werner syndrome protein and other RecQ helicases.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Application of phage display to high throughput antibody generation and characterization

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Reevaluation of telomerase inhibition by quadruplex ligands and their mechanisms of action

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

How telomeres are replicated

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Endogenous gamma-H2AX-ATM-Chk2 checkpoint activation in Bloom's syndrome helicase deficient cells is related to DNA replication arrested forks

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

A simple vector system to improve performance and utilisation of recombinant antibodies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

A general protocol for evaluating the specific effects of DNA replication inhibitors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

A retarded rate of DNA chain growth in Bloom's syndrome

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4508891

Visualization of DNA replication on individual Epstein-Barr virus episomes

3 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201410061

Progressive activation of DNA replication initiation in large domains of the immunoglobulin heavy chain locus during B cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201410061

Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201410061

The Bloom's syndrome helicase can promote the regression of a model replication fork.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201410061

Highly Efficient G-Quadruplex Recognition by Bisquinolinium Compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201410061

Detection of G-quadruplex DNA in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201410061

Human werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/26195664

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chromosome instability and tumor predisposition inversely correlate with BLM protein levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/26195664