Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein (Q28771710)

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title

Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein (English)

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1 February 2020

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GOA release 2020-03-11

amyloid-beta binding

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GOA release 2020-03-11

author

Alexandra J Mably

4

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Michael J Rowan

8

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author name string

Igor Klyubin

2

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Michael Scott

6

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Andrew E Barry

1

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Jessica M Mc Donald

3

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Michael A Farrell

5

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Dominic M Walsh

7

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language of work or name

English

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publication date

1 May 2011

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published in

Journal of Neuroscience

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volume

31

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issue

20

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page(s)

7259-7263

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The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging.

1 February 2020

cites work

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12 December 2020

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

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12 December 2020

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

12 December 2020

beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology

1 reference

12 December 2020

Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor

1 reference

12 December 2020

Uptake and pathogenic effects of amyloid beta peptide 1-42 are enhanced by integrin antagonists and blocked by NMDA receptor antagonists

1 reference

12 December 2020

Alzheimer's disease is a synaptic failure

1 reference

12 December 2020

LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

1 reference

12 December 2020

Alpha2beta1 and alphaVbeta1 integrin signaling pathways mediate amyloid-beta-induced neurotoxicity

1 reference

12 December 2020

Solution state characterization of amyloid beta-derived diffusible ligands

1 reference

12 December 2020

Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization

1 reference

12 December 2020

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

1 reference

12 December 2020

Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus

1 reference

12 December 2020

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

1 reference

12 December 2020

Regulation of group I metabotropic glutamate receptor trafficking and signaling by the caveolar/lipid raft pathway

1 reference

12 December 2020

RAGE and Alzheimer's disease: a progression factor for amyloid-beta-induced cellular perturbation?

1 reference

12 December 2020

Formation and maintenance of Alzheimer's disease beta-amyloid plaques in the absence of microglia

1 reference

12 December 2020

Prion protein and Alzheimer disease

1 reference

12 December 2020

Alzheimer's disease: synaptic dysfunction and Abeta

1 reference

12 December 2020

Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein

1 reference

12 December 2020

Lipid rafts are primary mediators of amyloid oxidative attack on plasma membrane

1 reference

12 December 2020

The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia.

1 reference

12 December 2020

Memory impairment in transgenic Alzheimer mice requires cellular prion protein

1 reference

12 December 2020

Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5

1 reference

12 December 2020

In vivo composition of NMDA receptor signaling complexes differs between membrane subdomains and is modulated by PSD-95 and PSD-93

1 reference

12 December 2020

Interaction between human prion protein and amyloid-beta (Abeta) oligomers: role OF N-terminal residues

1 reference

12 December 2020

The monomer state of beta-amyloid: where the Alzheimer's disease protein meets physiology

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12 December 2020

Prion protein and Abeta-related synaptic toxicity impairment

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12 December 2020

The prion protein as a receptor for amyloid-beta.

1 reference

12 December 2020

Anti-PrPC monoclonal antibody infusion as a novel treatment for cognitive deficits in an Alzheimer's disease model mouse

1 reference

12 December 2020

Differential binding of vascular cell-derived proteoglycans (perlecan, biglycan, decorin, and versican) to the beta-amyloid protein of Alzheimer's disease

1 reference

12 December 2020

Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments.

1 reference

12 December 2020

Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.

1 reference

12 December 2020

Mapping the prion protein using recombinant antibodies

1 reference

12 December 2020

10.1523/JNEUROSCI.6500-10.2011

Identifiers

DOI

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