AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs (Q28834527)

Androgen dependent TFPI regulating protein

ChEBI release 2020-05-28

1 reference

GOA release 2020-03-11

1 reference

long-chain fatty acid catabolic process

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1

William H Parsons

0 references

Matthew J. Kolar

Matthew J Kolar

2

0 references

Siddhesh S Kamat

Siddhesh S Kamat

3

0 references

Benjamin Cravatt

9

Benjamin F Cravatt

0 references

Barbara Kahn

7

Barbara B Kahn

0 references

author name string

Armand B Cognetta

4

0 references

Jonathan J Hulce

5

0 references

Enrique Saez

6

0 references

Alan Saghatelian

describes a project that uses

8

0 references

language of work or name

English

0 references

publication date

May 2016

0 references

published in

Nature Chemical Biology

0 references

volume

12

0 references

issue

5

0 references

page(s)

367-72

0 references

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4837090/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Activity-based probes for rhomboid proteases discovered in a mass spectrometry-based assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Activity-based protein profiling of the Escherichia coli GlpG rhomboid protein delineates the catalytic core

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

The Enzyme Function Initiative

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Activity-based proteomics of enzyme superfamilies: serine hydrolases as a case study

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Unconventional serine proteases: variations on the catalytic Ser/His/Asp triad configuration

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

The HHpred interactive server for protein homology detection and structure prediction

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Large-scale analysis of the yeast proteome by multidimensional protein identification technology

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Catalytic triads and their relatives

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Why cells need intramembrane proteases - a mechanistic perspective

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Chemical Tools for the Study of Intramembrane Proteases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Selective N-Hydroxyhydantoin Carbamate Inhibitors of Mammalian Serine Hydrolases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Current developments in activity-based protein profiling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Enzyme inhibitor discovery by activity-based protein profiling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Divergence and convergence in enzyme evolution: parallel evolution of paraoxonases from quorum-quenching lactonases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Novel protein ADTRP regulates TFPI expression and function in human endothelial cells in normal conditions and in response to androgen

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

The metabolic serine hydrolases and their functions in mammalian physiology and disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Quantitative reactivity profiling predicts functional cysteines in proteomes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Activity-based probes that target functional subclasses of phospholipases in proteomes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Intramembrane-cleaving proteases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Detergent binding explains anomalous SDS-PAGE migration of membrane proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Activity-based protein profiling: applications to biomarker discovery, in vivo imaging and drug discovery

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Cloning of androgen-inducible gene 1 (AIG1) from human dermal papilla cells.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Activity-based protein profiling: the serine hydrolases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

Biochemical and genetic evidence for distinct membrane-bound and cytosolic sialic acid O-acetyl-esterases: serine-active-site enzymes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

A streamlined platform for high-content functional proteomics of primary human specimens

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2051

Profiling serine hydrolase activities in complex proteomes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2051

Natural killer T cells in health and disease

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2051

Direct visualization of serine hydrolase activities in complex proteomes using fluorescent active site-directed probes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4837090

AIG1 is a novel Pirh2-interacting protein that activates the NFAT signaling pathway

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27018888

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Class assignment of sequence-unrelated members of enzyme superfamilies by activity-based protein profiling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27018888