Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes (Q34300985)

1 August 2017

Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes (English)

1 reference

1 August 2017

4

Ku-Lung Hsu

1 reference

1 August 2017

14

Benjamin F Cravatt

1 reference

1 August 2017

Alexander Adibekian

1

1 reference

1 August 2017

Brent R Martin

2

1 reference

1 August 2017

Jae Won Chang

3

1 reference

1 August 2017

Katsunori Tsuboi

5

1 reference

1 August 2017

Daniel A Bachovchin

6

1 reference

1 August 2017

Anna E Speers

7

1 reference

1 August 2017

Steven J Brown

8

1 reference

1 August 2017

Timothy Spicer

9

1 reference

1 August 2017

Virneliz Fernandez-Vega

10

1 reference

1 August 2017

Jill Ferguson

11

1 reference

1 August 2017

Peter S Hodder

12

1 reference

1 August 2017

Hugh Rosen

13

1 reference

1 August 2017

language of work or name

English

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publication date

12 June 2012

1 reference

Journal of the American Chemical Society

1 August 2017

1 reference

1 August 2017

134

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1 August 2017

25

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1 August 2017

10345-10348

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How chemoproteomics can enable drug discovery and development

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

New approaches for dissecting protease functions to improve probe development and drug discovery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

Global profiling of dynamic protein palmitoylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

The metabolic serine hydrolases and their functions in mammalian physiology and disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

A potent and selective inhibitor of KIAA1363/AADACL1 that impairs prostate cancer pathogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

Lipidomics at the interface of structure and function in systems biology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

Small-molecule inhibition of APT1 affects Ras localization and signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

Identification of selective inhibitors of uncharacterized enzymes by high-throughput screening with fluorescent activity-based probes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

Large-scale profiling of protein palmitoylation in mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

Activity-based protein profiling: from enzyme chemistry to proteomic chemistry

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

High-throughput screening assays for the identification of chemical probes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

Profiling enzyme activities in vivo using click chemistry methods

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

Characterization of Saccharomyces cerevisiae acyl-protein thioesterase 1, the enzyme responsible for G protein alpha subunit deacylation in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

Sequence, expression in Escherichia coli, and characterization of lysophospholipase II.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

A cytoplasmic acyl-protein thioesterase that removes palmitate from G protein alpha subunits and p21(RAS)

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

Purification, cDNA cloning, and regulation of lysophospholipase from rat liver

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

Synthesis and evaluation of acyl protein thioesterase 1 (APT1) inhibitors.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

Depalmitoylation of endothelial nitric-oxide synthase by acyl-protein thioesterase 1 is potentiated by Ca(2+)-calmodulin

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3392194

28 October 2018

Identifiers

DOI

10.1021/JA303400U

1 reference

1 August 2017

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1 August 2017

1 reference