TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion (Q28975741)

21 March 2017

title

TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion (English)

1 reference

Phosphatase and tensin homolog

21 March 2017

main subject

1 reference

negative regulation of protein kinase B signaling

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

1 reference

Nirmalya Dey

1

1 reference

21 March 2017

Nandini Ghosh-Choudhury

series ordinal

2

1 reference

21 March 2017

Balakuntalam S. Kasinath

series ordinal

3

1 reference

21 March 2017

Goutam Ghosh Choudhury

series ordinal

4

1 reference

21 March 2017

language of work or name

English

0 references

publication date

1 January 2012

1 reference

21 March 2017

1 reference

21 March 2017

volume

7

1 reference

21 March 2017

issue

8

1 reference

21 March 2017

page(s)

e42316

1 reference

Creative Commons Attribution 4.0 International

21 March 2017

copyright license

start time

3 August 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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23 March 2017

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23 March 2017

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23 March 2017

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23 March 2017

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7 April 2017

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors.

3 June 2018

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3 June 2018

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3 June 2018

1 reference

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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Protein kinase B activation and lamellipodium formation are independent phosphoinositide 3-kinase-mediated events differentially regulated by endogenous Ras.

3 June 2018

1 reference

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Managing microvascular complications of diabetes with microRNAs

3 June 2018

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Akt kinase targets association of CBP with SMAD 3 to regulate TGFbeta-induced expression of plasminogen activator inhibitor-1.

26 November 2018

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Chronic kidney disease progression.

26 November 2018

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Inhibition of mTOR signaling with rapamycin attenuates renal hypertrophy in the early diabetic mice

26 November 2018

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Role of mammalian target of rapamycin signaling in compensatory renal hypertrophy

26 November 2018

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Plasminogen activator inhibitor type-1 gene expression and induced migration in TGF-beta1-stimulated smooth muscle cells is pp60(c-src)/MEK-dependent

26 November 2018

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The Phosphatidylinositol 3-Kinase/Akt Pathway Enhances Smad3-stimulated Mesangial Cell Collagen I Expression in Response to Transforming Growth Factor-β1

26 November 2018

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Tyrosine phosphorylation-dependent PI 3 kinase/Akt signal transduction regulates TGFbeta-induced fibronectin expression in mesangial cells

26 November 2018

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26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411779

The nuclear import function of Smad2 is masked by SARA and unmasked by TGFbeta-dependent phosphorylation.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411779

Mesangial cells express PDGF mRNAs and proliferate in response to PDGF

26 November 2018

1 reference

12 December 2020

Involvement of PKC-alpha in PDGF-mediated mitogenic signaling in human mesangial cells

1 reference

12 December 2020

PDGF-mediated activation of phosphatidylinositol 3 kinase in human mesangial cells

1 reference

12 December 2020

Transgenic mice with increased plasma levels of TGF-beta 1 develop progressive renal disease

1 reference

12 December 2020

Quantification of glomerular TGF-beta 1 mRNA in patients with diabetes mellitus

1 reference

12 December 2020

Transforming growth factor β1 represses proximal tubular cell microRNA-192 expression through decreased hepatocyte nuclear factor DNA binding

1 reference

12 December 2020

High glucose, high insulin, and their combination rapidly induce laminin-beta1 synthesis by regulation of mRNA translation in renal epithelial cells

1 reference

12 December 2020

Evidence that TGF-beta should be a therapeutic target in diabetic nephropathy

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0042316

Identifiers

DOI

1 reference

ADS bibcode

2012PLoSO...742316D

0 references

1 reference

1 reference

1 reference