Dishevelled Dmel_CG18361 (Q29819592)

Dishevelled Dsh

1 reference

Ubiquitin-like domain superfamily

1 reference

Winged helix-like DNA-binding domain superfamily

1 reference

PDZ superfamily

1 reference

DIX domain superfamily

1 reference

DIX domain, protein family

1 reference

Dishevelled

1 reference

PDZ domain, protein family

1 reference

DEP domain, protein family

1 reference

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

1 reference

14 January 2019

Planar cell polarity controls directional Notch signaling in the Drosophila leg.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51140&geneProductId=UniProtKB:P51140

9 references

8 April 2019

Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

Zinc-dependent interaction between dishevelled and the Drosophila Wnt antagonist naked cuticle.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

An unconventional nuclear localization motif is crucial for function of the Drosophila Wnt/wingless antagonist Naked cuticle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

Naked cuticle targets dishevelled to antagonize Wnt signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

The PDZ protein Canoe/AF-6 links Ras-MAPK, Notch and Wingless/Wnt signaling pathways by directly interacting with Ras, Notch and Dishevelled

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

The Hippo pathway regulates Wnt/beta-catenin signaling

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

protein domain specific binding

IPI

1 reference

8 April 2019

Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

signaling receptor complex adaptor activity

IPI

1 reference

8 April 2019

The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with Dishevelled

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

phosphatidic acid binding

1 reference

8 April 2019

Electrochemical cues regulate assembly of the Frizzled/Dishevelled complex at the plasma membrane during planar epithelial polarization.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

1 reference

8 April 2019

The Adenomatous polyposis coli tumour suppressor is essential for Axin complex assembly and function and opposes Axin's interaction with Dishevelled

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

establishment of planar polarity

IDA

biological process

1 reference

8 April 2019

Functional dissection of phosphorylation of Disheveled in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

compound eye morphogenesis

1 reference

8 April 2019

Patterning the peripheral retina of the fly: decoding a gradient

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

establishment of tissue polarity

1 reference

8 April 2019

Roles of the JNK signaling pathway in Drosophila morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

multicellular organism development

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

border follicle cell migration

IEA

1 reference

8 April 2019

The planar polarity pathway promotes coordinated cell migration during Drosophila oogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

1 reference

8 April 2019

Planar polarity and actin dynamics in the epidermis of Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

1 reference

8 April 2019

Ubiquitin ligase HUWE1 regulates axon branching through the Wnt/β-catenin pathway in a Drosophila model for intellectual disability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

salivary gland morphogenesis

1 reference

8 April 2019

Different Wnt signals act through the Frizzled and RYK receptors during Drosophila salivary gland migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

motor neuron axon guidance

1 reference

8 April 2019

Wnt4 is a local repulsive cue that determines synaptic target specificity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

DWnt4 regulates cell movement and focal adhesion kinase during Drosophila ovarian morphogenesis

female gonad development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

synaptic target inhibition

1 reference

8 April 2019

Wnt4 is a local repulsive cue that determines synaptic target specificity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

imaginal disc-derived leg joint morphogenesis

1 reference

14 January 2019

Planar cell polarity controls directional Notch signaling in the Drosophila leg.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51140&geneProductId=UniProtKB:P51140

1 reference

8 April 2019

DWnt4 regulates cell movement and focal adhesion kinase during Drosophila ovarian morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

ovarian follicle cell development

retinal ganglion cell axon guidance

1 reference

8 April 2019

DWnt4 regulates the dorsoventral specificity of retinal projections in the Drosophila melanogaster visual system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

regulation of actin filament bundle assembly

1 reference

8 April 2019

Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

regulation of tube length, open tracheal system

IGI

1 reference

8 April 2019

Serrano (sano) functions with the planar cell polarity genes to control tracheal tube length.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

wing and notum subfield formation

1 reference

8 April 2019

Modulation of AP and DV signaling pathways by the homeotic gene Ultrabithorax during haltere development in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

intracellular signal transduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

establishment of epithelial cell apical/basal polarity

IEA

1 reference

8 April 2019

Fidelity in planar cell polarity signalling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

negative regulation of Notch signaling pathway

1 reference

14 January 2019

Planar cell polarity controls directional Notch signaling in the Drosophila leg.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51140&geneProductId=UniProtKB:P51140

positive regulation of axon extension

1 reference

8 April 2019

The Formin DAAM Functions as Molecular Effector of the Planar Cell Polarity Pathway during Axonal Development in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

regulation of compound eye pigmentation

IGI

1 reference

8 April 2019

Organization of the peripheral fly eye: the roles of Snail family transcription factors in peripheral retinal apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

1 reference

8 April 2019

Wingless signaling regulates the maintenance of ovarian somatic stem cells in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

1 reference

8 April 2019

A signaling network for patterning of neuronal connectivity in the Drosophila brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

Spatially defined Dsh-Lgl interaction contributes to directional tissue morphogenesis

epidermis morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

canonical Wnt signaling pathway

8 references

16 July 2018

The wingless signaling pathway is directly involved in Drosophila heart development

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51140&geneProductId=UniProtKB:P51140

16 July 2018

DWnt4 regulates cell movement and focal adhesion kinase during Drosophila ovarian morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51140&geneProductId=UniProtKB:P51140

16 July 2018

Membrane Targeting of Disheveled Can Bypass the Need for Arrow/LRP5

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51140&geneProductId=UniProtKB:P51140

16 July 2018

The wingless signalling pathway and the patterning of the wing margin in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51140&geneProductId=UniProtKB:P51140

16 July 2018

Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51140&geneProductId=UniProtKB:P51140

16 July 2018

Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51140&geneProductId=UniProtKB:P51140

16 July 2018

Membrane Targeting of Disheveled Can Bypass the Need for Arrow/LRP5

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51140&geneProductId=UniProtKB:P51140

16 July 2018

Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=P51140&geneProductId=UniProtKB:P51140

1 reference

8 April 2019

The wingless signaling pathway is directly involved in Drosophila heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

establishment of epithelial cell planar polarity

1 reference

8 April 2019

Spatially defined Dsh-Lgl interaction contributes to directional tissue morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

positive regulation of axon guidance

1 reference

8 April 2019

The Formin DAAM Functions as Molecular Effector of the Planar Cell Polarity Pathway during Axonal Development in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

imaginal disc-derived wing margin morphogenesis

1 reference

8 April 2019

The wingless signalling pathway and the patterning of the wing margin in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

ovarian follicle cell development

3 references

8 April 2019

Notch signaling through tramtrack bypasses the mitosis promoting activity of the JNK pathway in the mitotic-to-endocycle transition of Drosophila follicle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

BMP signaling is required for controlling somatic stem cell self-renewal in the Drosophila ovary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

Quantitative microscopy of the Drosophila ovary shows multiple niche signals specify progenitor cell fate.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

compound eye photoreceptor cell differentiation

IGI

1 reference

8 April 2019

The APC/C Coordinates Retinal Differentiation with G1 Arrest through the Nek2-Dependent Modulation of Wingless Signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

canonical Wnt signaling pathway

9 references

8 April 2019

Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

The wingless signalling pathway and the patterning of the wing margin in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

The wingless signaling pathway is directly involved in Drosophila heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

DWnt4 regulates cell movement and focal adhesion kinase during Drosophila ovarian morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

Membrane Targeting of Disheveled Can Bypass the Need for Arrow/LRP5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

Membrane Targeting of Disheveled Can Bypass the Need for Arrow/LRP5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

Wnt/Wingless signaling through beta-catenin requires the function of both LRP/Arrow and frizzled classes of receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

Wnt signaling pathway, planar cell polarity pathway

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140

positive regulation of signal transduction

TAS

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51140