The Hippo pathway regulates Wnt/beta-catenin signaling (Q24307606)

Large tumor suppressor kinase 1

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Wnt family member 3A

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casein kinase 1 delta

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Serine/threonine kinase 3

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Large tumor suppressor kinase 2

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WW domain containing transcription regulator 1

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catenin beta 1

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negative regulation of canonical Wnt signaling pathway

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Dishevelled Dmel_CG18361

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Yorkie Dmel_CG4005

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Hippo Dmel_CG11228

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Warts Dmel_CG12072

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author

Anthony Pawson

8

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Xaralabos Varelas

Xaralabos Varelas

1

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Walter Hunziker

Walter Hunziker

9

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Alex Gregorieff

5

Alex Gregorieff

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Jeffrey L. Wrana

11

Jeffrey L Wrana

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author name string

Bryan W Miller

2

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Richelle Sopko

3

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Siyuan Song

4

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Frederic A Fellouse

6

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Rui Sakuma

7

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Helen McNeill

10

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Liliana Attisano

The casein kinase I family in Wnt signaling

12

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language of work or name

English

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publication date

20 April 2010

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published in

Developmental Cell

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volume

18

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issue

4

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page(s)

579-91

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cites work

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https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Molecular regulation of kidney development: is the answer blowing in the Wnt?

1 reference

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7 January 2021

Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless

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7 January 2021

Interaction between the internal motif KTXXXI of Idax and mDvl PDZ domain

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https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

The Hippo-YAP pathway: new connections between regulation of organ size and cancer

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7 January 2021

The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Wnt/beta-catenin signaling in development and disease

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7 January 2021

Elucidation of a universal size-control mechanism in Drosophila and mammals

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7 January 2021

Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

The tumor-suppressor gene fat controls tissue growth upstream of expanded in the hippo signaling pathway.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

The fat cadherin acts through the hippo tumor-suppressor pathway to regulate tissue size.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway.

1 reference

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7 January 2021

The salvador-warts-hippo pathway is required for epithelial proliferation and axis specification in Drosophila

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Expanded and fat regulate growth and differentiation in the Drosophila eye through multiple signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Direct and long-range action of a wingless morphogen gradient

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https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis

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https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Application of an integrated physical and functional screening approach to identify inhibitors of the Wnt pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Delineation of a Fat tumor suppressor pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Filling out the Hippo pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Wnt signaling in disease and in development

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https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin gene

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https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Apc deficiency predisposes to renal carcinoma in the mouse

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https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1

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7 January 2021

Simple and efficient production of embryonic stem cell-embryo chimeras by coculture

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https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Crystal structure of a conformation-selective casein kinase-1 inhibitor

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https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

beta-catenin is a target for the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

High-throughput mapping of a dynamic signaling network in mammalian cells

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https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Functional genomic analysis of the Wnt-wingless signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

TAZ, a transcriptional modulator of mesenchymal stem cell differentiation

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https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

TAZ promotes PC2 degradation through a SCFbeta-Trcp E3 ligase complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ

1 reference

https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

Transcriptional cooperation between the transforming growth factor-beta and Wnt pathways in mammary and intestinal tumorigenesis

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https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

In vivo regulation of Yorkie phosphorylation and localization.

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https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity

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https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021

The hippo pathway promotes Notch signaling in regulation of cell differentiation, proliferation, and oocyte polarity

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https://api.crossref.org/works/10.1016%2FJ.DEVCEL.2010.03.007

7 January 2021