Divergent modulation of Src-family kinase regulatory interactions with ATP-competitive inhibitors. (Q30009417)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24946274%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Divergent modulation of Src-family kinase regulatory interactions with ATP-competitive inhibitors (English)

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20 March 2020

5

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20 March 2020

author name string

Stephen E Leonard

1

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20 March 2020

A C Register

2

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20 March 2020

Ratika Krishnamurty

3

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20 March 2020

Gabriel J Brighty

4

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20 March 2020

publication date

2 July 2014

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20 March 2020

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20 March 2020

volume

9

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20 March 2020

issue

8

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20 March 2020

page(s)

1894-1905

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describes a project that uses

20 March 2020

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4136698/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Conformation-Selective ATP-Competitive Inhibitors Control Regulatory Interactions and Noncatalytic Functions of Mitogen-Activated Protein Kinases

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NMR reveals the allosteric opening and closing of Abelson tyrosine kinase by ATP-site and myristoyl pocket inhibitors

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Active site profiling reveals coupling between domains in SRC-family kinases

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Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors

22 May 2017

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22 May 2017

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22 May 2017

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22 May 2017

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Crystal structures of c-Src reveal features of its autoinhibitory mechanism

22 May 2017

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The 2.35 A crystal structure of the inactivated form of chicken Src: a dynamic molecule with multiple regulatory interactions

22 May 2017

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22 May 2017

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22 May 2017

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Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src)

22 May 2017

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CSK: a protein-tyrosine kinase involved in regulation of src family kinases

22 May 2017

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22 May 2017

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22 May 2017

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22 May 2017

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Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity

3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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Src signaling in cancer invasion

3 June 2018

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3 June 2018

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3 June 2018

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3 June 2018

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Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase

3 June 2018

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Protein-protein interactions in the allosteric regulation of protein kinases

3 June 2018

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N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor

3 June 2018

1 reference

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Conformational basis for SH2-Tyr(P)527 binding in Src inactivation

3 June 2018

1 reference

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Domains, motifs, and scaffolds: the role of modular interactions in the evolution and wiring of cell signaling circuits.

3 June 2018

1 reference

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High yield bacterial expression of active c-Abl and c-Src tyrosine kinases

3 June 2018

1 reference

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Endogenous and synthetic inhibitors of the Src-family protein tyrosine kinases

3 June 2018

1 reference

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The crystal structure of a c-Src complex in an active conformation suggests possible steps in c-Src activation

3 June 2018

1 reference

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Src family kinases, key regulators of signal transduction

3 June 2018

1 reference

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Protein tyrosine kinases Src and Csk: a tail's tale

3 June 2018

1 reference

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SH3-SH2 domain orientation in Src kinases: NMR studies of Fyn.

3 June 2018

1 reference

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Src in cancer: deregulation and consequences for cell behaviour

3 June 2018

1 reference

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SH3-dependent stimulation of Src-family kinase autophosphorylation without tail release from the SH2 domain in vivo

3 June 2018

1 reference

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Dynamic coupling between the SH2 and SH3 domains of c-Src and Hck underlies their inactivation by C-terminal tyrosine phosphorylation

3 June 2018

1 reference

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SH2-kinase linker mutations release Hck tyrosine kinase and transforming activities in Rat-2 fibroblasts.

3 June 2018

1 reference

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Intramolecular regulatory interactions in the Src family kinase Hck probed by mutagenesis of a conserved tryptophan residue.

3 June 2018

1 reference

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Peptide and protein phosphorylation by protein tyrosine kinase Csk: insights into specificity and mechanism

3 June 2018

1 reference

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The role of the linker between the SH2 domain and catalytic domain in the regulation and function of Src.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136698

Suppression of c-Src activity by C-terminal Src kinase involves the c-Src SH2 and SH3 domains: analysis with Saccharomyces cerevisiae

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136698

Autophosphorylation of purified c-Src at its primary negative regulation site.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136698

Prevention of MKK6-dependent activation by binding to p38alpha MAP kinase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136698

Common in vitro substrate specificity and differential Src homology 2 domain accessibility displayed by two members of the Src family of protein-tyrosine kinases, c-Src and Hck.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4136698

26 November 2018

Identifiers

DOI

10.1021/CB500371G

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24946274%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24946274%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24946274%20AND%20SRC:MED&resulttype=core&format=json