Detection of nanosecond time scale side-chain jumps in a protein dissolved in water/glycerol solvent (Q30157209)

8 June 2017

title

Detection of nanosecond time scale side-chain jumps in a protein dissolved in water/glycerol solvent (English)

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8 June 2017

3

Nikolai R Skrynnikov

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8 June 2017

Jun Xu

1

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8 June 2017

Yi Xue

series ordinal

2

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8 June 2017

language of work or name

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7 July 2009

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Journal of Biomolecular NMR

8 June 2017

published in

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8 June 2017

volume

45

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8 June 2017

issue

1-2

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8 June 2017

page(s)

57-72

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GPD1, which encodes glycerol-3-phosphate dehydrogenase, is essential for growth under osmotic stress in Saccharomyces cerevisiae, and its expression is regulated by the high-osmolarity glycerol response pathway

8 June 2017

cites work

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The role of protein-solvent hydrogen bond dynamics in the structural relaxation of a protein in glycerol versus water

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Deuterium spin probes of side-chain dynamics in proteins. 2. Spectral density mapping and identification of nanosecond time-scale side-chain motions

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Rotational Motion of a Solute Molecule in a Highly Viscous Liquid Studied by 13C NMR: 1,3-Dibromoadamantane in Polymeric Chlorotrifluoroethene

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Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

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Effects of calcium binding on the side-chain methyl dynamics of calbindin D9k: a 2H NMR relaxation study.

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Isotope labeling strategies for the study of high-molecular-weight proteins by solution NMR spectroscopy.

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What contributions to protein side-chain dynamics are probed by NMR experiments? A molecular dynamics simulation analysis

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Slaving: solvent fluctuations dominate protein dynamics and functions

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Long-range dynamic effects of point mutations propagate through side chains in the serine protease inhibitor eglin c.

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Vapor pressure osmometry studies of osmolyte-protein interactions: implications for the action of osmoprotectants in vivo and for the interpretation of "osmotic stress" experiments in vitro

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Correct protein folding in glycerol

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12 December 2020

Crystal structure of a Src-homology 3 (SH3) domain

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12 December 2020

Glycerol decreases the volume and compressibility of protein interior

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12 December 2020

Residual methyl protonation in perdeuterated proteins for multi-dimensional correlation experiments in MAS solid-state NMR spectroscopy

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Protein and solvent dynamics: how strongly are they coupled?

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Dynamics of protein and peptide hydration

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Glycerol concentrations required for the successful vitrification of cocktail conditions in a high-throughput crystallization screen.

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Asymmetric doublets in MAS NMR: coherent and incoherent mechanisms

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Dynamics of methyl groups in proteins as studied by proton-detected 13C NMR spectroscopy. Application to the leucine residues of staphylococcal nuclease

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Structure, thermostability, and conformational flexibility of hen egg-white lysozyme dissolved in glycerol

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Methyl rotation barriers in proteins from 2H relaxation data. Implications for protein structure

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Rotational diffusion anisotropy of proteins from simultaneous analysis of 15N and 13C alpha nuclear spin relaxation

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Quantitative 13C and 2H NMR relaxation studies of the 723-residue enzyme malate synthase G reveal a dynamic binding interface

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Cryocooling of Macromolecular Crystals: Optimization Methods

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Slow dynamics in folded and unfolded states of an SH3 domain

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The response of internal dynamics to hydrophobic core mutations in the SH3 domain from the Fyn tyrosine kinase

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Protein side-chain dynamics as observed by solution- and solid-state NMR spectroscopy: a similarity revealed

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Correlation between dynamics and high affinity binding in an SH2 domain interaction

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Characterization of leucine side-chain reorientation in collagen-fibrils by solid-state 2H NMR.

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Human type-alpha transforming growth factor undergoes slow conformational exchange between multiple backbone conformations as characterized by nitrogen-15 relaxation measurements

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Mechanism of protein stabilization by glycerol: preferential hydration in glycerol-water mixtures

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1H and 15N NMR assignment and solution structure of the SH3 domain of spectrin: comparison of unrefined and refined structure sets with the crystal structure

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Backbone and side chain dynamics of mutant calmodulin-peptide complexes

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Determination of protein rotational correlation time from NMR relaxation data at various solvent viscosities.

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The Role of Glycerol in the Osmotic Regulation of the Halophilic Alga Dunaliella parva

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An NMR experiment for the accurate measurement of heteronuclear spin-lock relaxation rates

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Frictional models for stochastic simulations of proteins

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Structure of a protein determined by solid-state magic-angle-spinning NMR spectroscopy

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The Effects of Mutations on Motions of Side-chains in Protein L Studied by 2H NMR Dynamics and Scalar Couplings

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Effect of osmolytes on the exchange rates of backbone amide protons in proteins.

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12 December 2020

Protein side-chain dynamics observed by solution- and solid-state NMR: comparative analysis of methyl 2H relaxation data

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Relating side-chain mobility in proteins to rotameric transitions: insights from molecular dynamics simulations and NMR.

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A robust and cost-effective method for the production of Val, Leu, Ile (delta 1) methyl-protonated 15N-, 13C-, 2H-labeled proteins

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Characterization of Dynamics of Perdeuterated Proteins by MAS Solid-State NMR

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Modeling the electrophoresis of rigid polyions: application to lysozyme

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Molecular level probing of preferential hydration and its modulation by osmolytes through the use of pyranine complexed to hemoglobin.

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Anisotropic rotational diffusion of perdeuterated HIV protease from 15N NMR relaxation measurements at two magnetic fields

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Backbone dynamics of Escherichia coli ribonuclease HI: correlations with structure and function in an active enzyme

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Effects of protein stabilizing agents on thermal backbone motions: a disulfide trapping study

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HYDRONMR: prediction of NMR relaxation of globular proteins from atomic-level structures and hydrodynamic calculations

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Structure, dynamics, and energetics of water at the surface of a small globular protein: A molecular dynamics simulation

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Improved magnetization alignment schemes for spin-lock relaxation experiments

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Crystallization in the presence of glycerol displaces water molecules in the structure of thaumatin

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Preferential hydration of lysozyme in water/glycerol mixtures: A small-angle neutron scattering study

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12 December 2020

Comparison of methyl rotation axis order parameters derived from model-free analyses of (2)H and (13)C longitudinal and transverse relaxation rates measured in the same protein sample

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Analysis of the backbone dynamics of interleukin-1 beta using two-dimensional inverse detected heteronuclear 15N-1H NMR spectroscopy

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12 December 2020

Use of glycerol, polyols and other protein structure stabilizing agents in protein crystallization.

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12 December 2020

Thermodynamic and kinetic examination of protein stabilization by glycerol

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12 December 2020

Side-chain dynamics of the SAP SH2 domain correlate with a binding hot spot and a region with conformational plasticity

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12 December 2020

10.1007/S10858-009-9336-9

Identifiers

DOI

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8 June 2017

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