Src family kinases phosphorylate the Bcr-Abl SH3-SH2 region and modulate Bcr-Abl transforming activity (Q30159676)

8 June 2017

Src family kinases phosphorylate the Bcr-Abl SH3-SH2 region and modulate Bcr-Abl transforming activity (English)

1 reference

8 June 2017

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John R Engen

8

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author name string

Malcolm A Meyn

1

1 reference

8 June 2017

Matthew B Wilson

2

1 reference

8 June 2017

Fadi A Abdi

3

1 reference

8 June 2017

Nathalie Fahey

4

1 reference

8 June 2017

Anthony P Schiavone

5

1 reference

8 June 2017

Jiong Wu

6

1 reference

8 June 2017

James M Hochrein

7

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8 June 2017

Thomas E Smithgall

9

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8 June 2017

language of work or name

English

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publication date

15 August 2006

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Journal of Biological Chemistry

8 June 2017

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8 June 2017

281

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8 June 2017

41

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8 June 2017

30907-30916

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Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining

8 June 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

The BCR-ABL story: bench to bedside and back

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Studying the pathogenesis of BCR-ABL+ leukemia in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Transformation of myeloid leukemia cells to cytokine independence by Bcr-Abl is suppressed by kinase-defective Hck

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

The Src family kinase Hck interacts with Bcr-Abl by a kinase-independent mechanism and phosphorylates the Grb2-binding site of Bcr

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Structure and regulation of Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Overriding imatinib resistance with a novel ABL kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Targeted CML therapy: controlling drug resistance, seeking cure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

SRC family kinase activity is required for murine embryonic stem cell growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

HIV-1 Nef promotes survival of myeloid cells by a Stat3-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

HIV-1 Nef promotes survival of TF-1 macrophages by inducing Bcl-XL expression in an extracellular signal-regulated kinase-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Structural basis for the autoinhibition of c-Abl tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Pyrrolo[2,3-d]pyrimidines containing diverse N-7 substituents as potent inhibitors of Lck.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Regulation of the c-Abl and Bcr-Abl tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Autoinhibition of Bcr-Abl through its SH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

A myristoyl/phosphotyrosine switch regulates c-Abl

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Phosphorylation and structure-based functional studies reveal a positive and a negative role for the activation loop of the c-Abl tyrosine kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

c-Abl is an effector of Src for growth factor-induced c-myc expression and DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

Two distinct phosphorylation pathways have additive effects on Abl family kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M605902200

21 January 2018

Identifiers

DOI

10.1074/JBC.M605902200

1 reference

release_xtunqxzy5jdqbk4nzqgrm6l3oi

8 June 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xtunqxzy5jdqbk4nzqgrm6l3oi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference