70Z/3 Cbl induces PLCγ1 activation in T lymphocytes via an alternate Lat- and Slp-76-independent signaling mechanism (Q30164758)

9 June 2017

70Z/3 Cbl induces PLC gamma 1 activation in T lymphocytes via an alternate Lat- and Slp-76-independent signaling mechanism (English)

1 reference

9 June 2017

70Z/3 Cbl induces PLCγ1 activation in T lymphocytes via an alternate Lat- and Slp-76-independent signaling mechanism (English)

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206318

signal transducing adaptor protein

28 December 2023

main subject

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12717426

28 December 2023

nuclear protein

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12717426

28 December 2023

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206318

28 December 2023

author name string

Maria-Concetta Verí

2

1 reference

9 June 2017

Cristiana Noviello

4

1 reference

9 June 2017

Rashmi Rawat

5

1 reference

9 June 2017

Sandy Jen

6

1 reference

9 June 2017

Ezio Bonvini

7

1 reference

9 June 2017

Barbara Rellahan

8

1 reference

9 June 2017

Laurie J. Graham

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12717426

28 December 2023

Karen E. DeBell

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12717426

28 December 2023

language of work or name

English

0 references

publication date

1 April 2003

1 reference

9 June 2017

24 April 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12717426

full work available at URL

28 December 2023

https://www.nature.com/articles/1206318.pdf

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206318

https://www.nature.com/articles/1206318

28 December 2023

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206318

28 December 2023

1 reference

9 June 2017

22

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9 June 2017

16

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9 June 2017

2493-2503

1 reference

Recruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signaling

9 June 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

Identification of Itk/Tsk Src homology 3 domain ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

Sequences surrounding the Src-homology 3 domain of phospholipase Cgamma-1 increase the domain's association with Cbl

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

Signal transduction by the TCR for antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

Cbl-mediated regulation of T cell receptor-induced AP1 activation. Implications for activation via the Ras signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

Transcriptional regulation of the T cell antigen receptor zeta subunit: identification of a tissue-restricted promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

Regulation of phosphoinositide-specific phospholipase C isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

Tec family kinases in lymphocyte signaling and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

Itk/Emt/Tsk activation in response to CD3 cross-linking in Jurkat T cells requires ZAP-70 and Lat and is independent of membrane recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

Cbl suppresses B cell receptor-mediated phospholipase C (PLC)-gamma2 activation by regulating B cell linker protein-PLC-gamma2 binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

Leucine zipper-mediated homodimerization of the adaptor protein c-Cbl. A role in c-Cbl's tyrosine phosphorylation and its association with epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Functional independence and interdependence of the Src homology domains of phospholipase C-gamma1 in B-cell receptor signal transduction.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Differential effects of Cbl and 70Z/3 Cbl on T cell receptor-induced phospholipase Cgamma-1 activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Pleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

The epidermal growth factor receptor is associated with phospholipase C-gamma 1 in meningiomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Overexpression of phospholipase C-gamma 1 in colorectal carcinomas is associated with overexpression of factors that bind its promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Cbl: complex formation and functional implications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

The Cbl protooncoprotein: a negative regulator of immune receptor signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Binding of ZAP-70 to phosphorylated T-cell receptor zeta and eta enhances its autophosphorylation and generates specific binding sites for SH2 domain-containing proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Elevated content of phospholipase C-gamma 1 in colorectal cancer tissues.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Overexpression of phosphoinositide-specific phospholipase Cgamma in NIH 3T3 cells promotes transformation and tumorigenicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Interaction of SLP adaptors with the SH2 domain of Tec family kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Cbl: many adaptations to regulate protein tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Stimulation of phospholipase C-gamma 1 membrane association by epidermal growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Beyond the RING: CBL proteins as multivalent adapters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

The oncogenic 70Z Cbl mutation blocks the phosphotyrosine binding domain-dependent negative regulation of ZAP-70 by c-Cbl in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Activation of nuclear factor of activated T cells-(NFAT) and activating protein 1 (AP-1) by oncogenic 70Z Cbl requires an intact phosphotyrosine binding domain but not Crk(L) or p85 phosphatidylinositol 3-kinase association

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Membrane raft-dependent regulation of phospholipase Cgamma-1 activation in T lymphocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Complex complexes: signaling at the TCR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Dual regulation of T cell receptor-mediated signaling by oncogenic Cbl mutant 70Z.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206318

7 January 2021

Adapting to multiple personalities: Cbl is also a RING finger ubiquitin ligase

26

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206318

28 December 2023

Identifiers

1 reference

Dimensions Publication ID

9 June 2017

0 references

1 reference