Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins (Q30175408)

9 June 2017

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title

Membrane-targeting of signalling molecules by SH2/SH3 domain-containing adaptor proteins (English)

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9 June 2017

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L Buday

1

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PubMed ID

10393272

9 June 2017

language of work or name

English

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publication date

1 July 1999

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Biochimica et Biophysica Acta

9 June 2017

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9 June 2017

1422

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9 June 2017

2

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9 June 2017

187-204

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A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps

9 June 2017

1 reference

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7 January 2021

Binding of SH2 domains of phospholipase C gamma 1, GAP, and Src to activated growth factor receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Binding of Transforming Protein, P47 gag-crk , to a Broad Range of Phosphotyrosine-containing Proteins

1 reference

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7 January 2021

Identification of domains of the v-crk oncogene product sufficient for association with phosphotyrosine-containing proteins

1 reference

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7 January 2021

Src homology region 2 domains direct protein-protein interactions in signal transduction

1 reference

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7 January 2021

A novel viral oncogene with structural similarity to phospholipase C

1 reference

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7 January 2021

SH2 domains recognize specific phosphopeptide sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Protein modules and signalling networks

1 reference

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7 January 2021

Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase

1 reference

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7 January 2021

Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Identification of a ten-amino acid proline-rich SH3 binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Affinity and specificity requirements for the first Src homology 3 domain of the Crk proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Orientation of peptide fragments from Sos proteins bound to the N-terminal SH3 domain of Grb2 determined by NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Cloning of ASH, a ubiquitous protein composed of one Src homology region (SH) 2 and two SH3 domains, from human and rat cDNA libraries

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Insulin stimulates sequestration of beta-adrenergic receptors and enhanced association of beta-adrenergic receptors with Grb2 via tyrosine 350

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

BLNK: a central linker protein in B cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Growth factor receptor-bound protein 2 SH2/SH3 domain binding to CD28 and its role in co-signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Shc, Grb2, Sos1, and a 150-kilodalton tyrosine-phosphorylated protein form complexes with Fms in hematopoietic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Thyroid hormone modulates the interaction between iron regulatory proteins and the ferritin mRNA iron-responsive element

1 reference

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7 January 2021

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

1 reference

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7 January 2021

Identification of vascular endothelial growth factor receptor-1 tyrosine phosphorylation sites and binding of SH2 domain-containing molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Identification of a second Grb2 binding site in the v-Fms tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Identification of small clusters of divergent amino acids that mediate the opposing effects of ras and Krev-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Uncoupling of Grb2 from the Met receptor in vivo reveals complex roles in muscle development

1 reference

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7 January 2021

Tyrosine phosphorylation of nicotinic acetylcholine receptor mediates Grb2 binding

1 reference

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7 January 2021

Intracellular signaling of the Ufo/Axl receptor tyrosine kinase is mediated mainly by a multi-substrate docking-site

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Position independence and proper developmental control of gamma-globin gene expression require both a 5' locus control region and a downstream sequence element

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Purification and characterization of an interleukin-1beta-converting enzyme family protease that activates cysteine protease P32 (CPP32)

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Shc and a novel 89-kDa component couple to the Grb2-Sos complex in fibroblast growth factor-2-stimulated cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Growth Hormone-promoted Tyrosyl Phosphorylation of SHC Proteins and SHC Association with Grb2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The DNA binding activity of C/EBP transcription factor is regulated in the G1 phase of the hepatocyte cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Signal transduction by the alpha 6 beta 4 integrin: distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The coupling of alpha6beta4 integrin to Ras-MAP kinase pathways mediated by Shc controls keratinocyte proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Interaction of Shc with Grb2 regulates association of Grb2 with mSOS

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Interactions of Cbl with two adapter proteins, Grb2 and Crk, upon T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Interactions of Cbl with Grb2 and phosphatidylinositol 3'-kinase in activated Jurkat cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Grb2 forms an inducible protein complex with CD28 through a Src homology 3 domain-proline interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The GTPase dynamin binds to and is activated by a subset of SH3 domains

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

A complex of GRB2-dynamin binds to tyrosine-phosphorylated insulin receptor substrate-1 after insulin treatment.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

SH3 domain-mediated interaction of dystroglycan and Grb2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

SH3 domain-dependent association of huntingtin with epidermal growth factor receptor signaling complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Grb2 interaction with MEK-kinase 1 is involved in regulation of Jun-kinase activities in response to epidermal growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Coupling of the murine protein tyrosine phosphatase PEST to the epidermal growth factor (EGF) receptor through a Src homology 3 (SH3) domain-mediated association with Grb2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Prolactin inhibits epidermal growth factor-induced Ras-MAPK signaling in mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

An Eps homology (EH) domain protein that binds to the Ral-GTPase target, RalBP1

1 reference

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7 January 2021

Interaction between Sam68 and Src family tyrosine kinases, Fyn and Lck, in T cell receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Stimulation through the T cell receptor leads to interactions between SHB and several signaling proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Wiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

In vivo functional analysis of the Ras exchange factor son of sevenless

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The Grb2 binding domain of mSos1 is not required for downstream signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Functional roles for the pleckstrin and Dbl homology regions in the Ras exchange factor Son-of-sevenless

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The solution structure of the pleckstrin homology domain of mouse Son-of-sevenless 1 (mSos1)

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

High affinity binding of the pleckstrin homology domain of mSos1 to phosphatidylinositol (4,5)-bisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The role of the PH domain in the signal-dependent membrane targeting of Sos.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Inhibition of mSOS-activity by binding of phosphatidylinositol 4,5-P2 to the mSOS pleckstrin homology domain

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The c-cbl proto-oncogene is preferentially expressed in thymus and testis tissue and encodes a nuclear protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

c-Cbl: a regulator of T cell receptor-mediated signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Molecules in focus: The c-Cbl oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Cbl: complex formation and functional implications

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Ras-dependent, Ca2+-stimulated activation of nuclear factor of activated T cells by a constitutively active Cbl mutant in T cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Regulation of the association of p120cbl with Grb2 in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Cbl-mediated regulation of T cell receptor-induced AP1 activation. Implications for activation via the Ras signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Ligation of the T-cell antigen receptor (TCR) induces association of hSos1, ZAP-70, phospholipase C-gamma 1, and other phosphoproteins with Grb2 and the zeta-chain of the TCR

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Divergent mechanisms for homologous desensitization of p21ras by insulin and growth factors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Insulin-stimulated disassociation of the SOS-Grb2 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Mechanisms of enhanced transmembrane signaling by an insulin receptor lacking a cytoplasmic beta-subunit domain

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Insulin stimulation of a MEK-dependent but ERK-independent SOS protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

EGF induced SOS phosphorylation in PC12 cells involves P90 RSK-2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

T cell receptor-induced phosphorylation of Sos requires activity of CD45, Lck, and protein kinase C, but not ERK.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Insulin receptor-mediated dissociation of Grb2 from Sos involves phosphorylation of Sos by kinase(s) other than extracellular signal-regulated kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

LAT palmitoylation: its essential role in membrane microdomain targeting and tyrosine phosphorylation during T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Association of Nck with tyrosine-phosphorylated SLP-76 in activated T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

A family of proteins that inhibit signalling through tyrosine kinase receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Identification of Nck family genes, chromosomal localization, expression, and signaling specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The SH2 and SH3 domain-containing Nck protein is oncogenic and a common target for phosphorylation by different surface receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The SH2/SH3 domain-containing protein Nck is recognized by certain anti-phospholipase C-gamma 1 monoclonal antibodies, and its phosphorylation on tyrosine is stimulated by platelet-derived growth factor and epidermal growth factor treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Phosphorylation of Nck in response to a variety of receptors, phorbol myristate acetate, and cyclic AMP

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

A single point mutation switches the specificity of group III Src homology (SH) 2 domains to that of group I SH2 domains

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Prediction and analysis of SH2 domain-phosphopeptide interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Tyrosine 1213 of Flt-1 is a major binding site of Nck and SHP-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Nck recruitment to Eph receptor, EphB1/ELK, couples ligand activation to c-Jun kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Hepatocyte growth factor induces activation of Nck and phospholipase C-gamma in lung carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The multiple endocrine neoplasia type 2B point mutation switches the specificity of the Ret tyrosine kinase towards cellular substrates that are susceptible to interact with Crk and Nck

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Binding of NCK to SOS and activation of ras-dependent gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Interactions between Src homology (SH) 2/SH3 adapter proteins and the guanylnucleotide exchange factor SOS are differentially regulated by insulin and epidermal growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

A Novel Ligand for SH3 Domains

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Interaction of the Nck adapter protein with p21-activated kinase (PAK1)

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The Ktr1p, Ktr3p, and Kre2p/Mnt1p mannosyltransferases participate in the elaboration of yeast O- and N-linked carbohydrate chains

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Characterization of interactions of Nck with Sos and dynamin

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Molecular cloning of p125Nap1, a protein that associates with an SH3 domain of Nck

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

A novel ligand for an SH3 domain of the adaptor protein Nck bears an SH2 domain and nuclear signaling motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Identification of a mouse p21Cdc42/Rac activated kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The Nck SH2/SH3 adaptor protein is present in the nucleus and associates with the nuclear protein SAM68

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The Wiskott-Aldrich syndrome protein-interacting protein (WIP) binds to the adaptor protein Nck

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Direct interaction of the Wiskott-Aldrich syndrome protein with the GTPase Cdc42

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Two species of human CRK cDNA encode proteins with distinct biological activities

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

c-Abl kinase regulates the protein binding activity of c-Crk

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Crk is required for apoptosis in Xenopus egg extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Inhibition of ras-induced germinal vesicle breakdown in Xenopus oocytes by rap-1B.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Enhancement of guanine-nucleotide exchange activity of C3G for Rap1 by the expression of Crk, CrkL, and Grb2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Crk interacts with tyrosine-phosphorylated p116 upon T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

CSF-1 stimulation induces the formation of a multiprotein complex including CSF-1 receptor, c-Cbl, PI 3-kinase, Crk-II and Grb2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

A 31-amino-acid N-terminal extension regulates c-Crk binding to tyrosine-phosphorylated proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Identification of Tyr-762 in the platelet-derived growth factor alpha-receptor as the binding site for Crk proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Both the SH2 and SH3 domains of human CRK protein are required for neuronal differentiation of PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Expression of the v-crk oncogene product in PC12 cells results in rapid differentiation by both nerve growth factor- and epidermal growth factor-dependent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Downstream of Crk adaptor signaling pathway: activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Guanine-nucleotide exchange protein C3G activates JNK1 by a ras-independent mechanism. JNK1 activation inhibited by kinase negative forms of MLK3 and DLK mixed lineage kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Paxillin is a major phosphotyrosine-containing protein during embryonic development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Localization of paxillin, a focal adhesion protein, to smooth muscle dense plaques, and the myotendinous and neuromuscular junctions of skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Ligation of the T cell antigen receptor induces tyrosine phosphorylation of p105CasL, a member of the p130Cas-related docking protein family, and its subsequent binding to the Src homology 2 domain of c-Crk

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Regulation of integrin-mediated p130(Cas) tyrosine phosphorylation in human B cells. A role for p59(Fyn) and SHP2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

The SH3 domain of Crk binds specifically to a conserved proline-rich motif in Eps15 and Eps15R

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Tyrosine phosphorylation of p130(cas) by bombesin, lysophosphatidic acid, phorbol esters, and platelet-derived growth factor. Signaling pathways and formation of a p130(cas)-Crk complex

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Nerve growth factor stimulates the tyrosine phosphorylation of endogenous Crk-II and augments its association with p130Cas in PC-12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

Adhesion through the interaction of lymphocyte function-associated antigen-1 with intracellular adhesion molecule-1 induces tyrosine phosphorylation of p130cas and its association with c-CrkII.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-4157%2899%2900005-2

7 January 2021

10.1016/S0304-4157(99)00005-2

Identifiers

DOI

1 reference

9 June 2017

1 reference

PubMed ID

10393272