Structure-based combinatorial protein engineering (SCOPE). (Q30331637)

18 June 2017

Structure-based combinatorial protein engineering (SCOPE). (English)

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18 June 2017

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Paul E O'Maille

1

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18 June 2017

Marina Bakhtina

series ordinal

2

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18 June 2017

Ming-Daw Tsai

series ordinal

3

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18 June 2017

language of work or name

English

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publication date

1 August 2002

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Journal of Molecular Biology

18 June 2017

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18 June 2017

321

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18 June 2017

4

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18 June 2017

677-691

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https://api.crossref.org/works/10.1016%2FS0022-2836%2802%2900675-7

18 June 2017

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7 January 2021

The exon theory of genes

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Identifying functional domains within terpene cyclases using a domain-swapping strategy

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Production and characterization of chimeric transferrins for the determination of the binding domains for bacterial transferrin receptors

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Module shuffling of a family F/10 xylanase: replacement of modules M4 and M5 of the FXYN of Streptomyces olivaceoviridis E-86 with those of the Cex of Cellulomonas fimi

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An investigation of the nature and function of module 10 in a family F/10 xylanase FXYN of Streptomyces olivaceoviridis E-86 by module shuffling with the Cex of Cellulomonas fimi and by site-directed mutagenesis

7 January 2021

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Assembly of an active enzyme by the linkage of two protein modules

7 January 2021

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New enzyme lineages by subdomain shuffling

7 January 2021

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Permutation of modules or secondary structure units creates proteins with basal enzymatic properties

7 January 2021

1 reference

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Foldability of barnase mutants obtained by permutation of modules or secondary structure units

7 January 2021

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A DNA polymerase with specificity for five base pairs

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DNA polymerase beta: pre-steady-state kinetic analysis and roles of arginine-283 in catalysis and fidelity.

7 January 2021

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The functional roles of mammalian DNA polymerase

7 January 2021

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Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair

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DNA polymerases: structural diversity and common mechanisms

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Structural design of a eukaryotic DNA repair polymerase: DNA polymerase beta.

7 January 2021

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Analysis of the complete nucleotide sequence of African swine fever virus

7 January 2021

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Characterization of an African swine fever virus 20-kDa DNA polymerase involved in DNA repair

7 January 2021

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Solution structure of a viral DNA polymerase X and evidence for a mutagenic function

7 January 2021

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Solution structure of a viral DNA repair polymerase

7 January 2021

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Compilation and alignment of DNA polymerase sequences

7 January 2021

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DNA polymerase beta-like nucleotidyltransferase superfamily: identification of three new families, classification and evolutionary history

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DNA polymerase beta belongs to an ancient nucleotidyltransferase superfamily

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Dali: a network tool for protein structure comparison

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The relation between the divergence of sequence and structure in proteins

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Modular structural units, exons, and function in chicken lysozyme

7 January 2021

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Parser for protein folding units

7 January 2021

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Hierarchic organization of domains in globular proteins

7 January 2021

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A procedure for detecting structural domains in proteins

7 January 2021

1 reference

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Compact units in proteins

7 January 2021

1 reference

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Rapid evolution of a protein in vitro by DNA shuffling

7 January 2021

1 reference

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Molecular evolution by staggered extension process (StEP) in vitro recombination

7 January 2021

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Human immunodeficiency virus reverse transcriptase substitutes for DNA polymerase I in Escherichia coli

7 January 2021

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Random mutagenesis of Thermus aquaticus DNA polymerase I: concordance of immutable sites in vivo with the crystal structure

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Detection and characterization of mammalian DNA polymerase beta mutants by functional complementation in Escherichia coli

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DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution

7 January 2021

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DNA shuffling method for generating highly recombined genes and evolved enzymes

7 January 2021

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DNA shuffling of a family of genes from diverse species accelerates directed evolution

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Random-priming in vitro recombination: an effective tool for directed evolution

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Random chimeragenesis by heteroduplex recombination

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Incremental truncation as a strategy in the engineering of novel biocatalysts

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Finding Cinderella's slipper--proteins that fit

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Libraries of hybrid proteins from distantly related sequences

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Creating multiple-crossover DNA libraries independent of sequence identity

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Modeling DNA mutation and recombination for directed evolution experiments

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Predicting crossover generation in DNA shuffling.

7 January 2021

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7 January 2021

Modeling DNA shuffling.

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Analysis of shuffled gene libraries

7 January 2021

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Directed evolution of proteins by exon shuffling

7 January 2021

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Random multi-recombinant PCR for the construction of combinatorial protein libraries

7 January 2021

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Functional proteins from a random-sequence library

7 January 2021

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A hierarchical approach to protein molecular evolution

7 January 2021

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Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism

7 January 2021

1 reference

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10.1016/S0022-2836(02)00675-7

7 January 2021

Identifiers

DOI

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18 June 2017

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