Differential detection of PAS-positive inclusions formed by the Z, Siiyama, and Mmalton variants of alpha1-antitrypsin. (Q30343942)

20 June 2017

Differential detection of PAS-positive inclusions formed by the Z, Siiyama, and Mmalton variants of alpha1-antitrypsin. (English)

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20 June 2017

1

Sabina Janciauskiene

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20 June 2017

Sten Eriksson

2

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20 June 2017

Francesco Callea

3

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20 June 2017

Meera Mallya

4

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20 June 2017

Aiwu Zhou

5

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20 June 2017

Kuniaki Seyama

6

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20 June 2017

Satoru Hata

7

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20 June 2017

David A Lomas

8

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20 June 2017

language of work or name

English

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publication date

1 November 2004

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20 June 2017

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20 June 2017

40

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20 June 2017

5

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20 June 2017

1203-1210

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Cleaved antitrypsin polymers at atomic resolution

20 June 2017

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Occurrence of Alpha-1-antitrypsin Deficiency in 155 Patients with Alcoholic Liver Disease

21 January 2018

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Alpha1-antitrypsin deficiency--a model for conformational diseases

21 January 2018

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7 January 2021

Topography of a 2.0 Å structure of α1-antitrypsin reveals targets for rational drug design to prevent conformational disease

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7 January 2021

Structure of a serpin-protease complex shows inhibition by deformation

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7 January 2021

The mechanism of Z alpha 1-antitrypsin accumulation in the liver

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7 January 2021

Alpha1-antitrypsin polymerization and the serpinopathies: pathobiology and prospects for therapy

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7 January 2021

Detection of circulating and endothelial cell polymers of Z and wild type alpha 1-antitrypsin by a monoclonal antibody

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7 January 2021

alpha 1-Antitrypsin Mmalton (Phe52-deleted) forms loop-sheet polymers in vivo. Evidence for the C sheet mechanism of polymerization.

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7 January 2021

Liver Disease in Alpha1-Antitrypsin Deficiency Detected by Screening of 200,000 Infants

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7 January 2021

Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency

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7 January 2021

Implications for function and therapy of a 2.9 A structure of binary-complexed antithrombin

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7 January 2021

A 2.6 A structure of a serpin polymer and implications for conformational disease

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7 January 2021

6-mer peptide selectively anneals to a pathogenic serpin conformation and blocks polymerization. Implications for the prevention of Z alpha(1)-antitrypsin-related cirrhosis

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7 January 2021

Pathogenic α1-Antitrypsin Polymers Are Formed by Reactive Loop-β-Sheet A Linkage

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7 January 2021

The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactions

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7 January 2021

Biological implications of a 3 A structure of dimeric antithrombin

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7 January 2021

Serpin alpha 1proteinase inhibitor probed by intrinsic tryptophan fluorescence spectroscopy

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7 January 2021

α1-Antitrypsin Polymerisation Can Occur by both Loop A and C Sheet Mechanisms

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7 January 2021

Acid Denaturation of alpha1-antitrypsin: characterization of a novel mechanism of serpin polymerization.

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7 January 2021

The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion

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7 January 2021

Polymerization of plasminogen activator inhibitor-1.

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7 January 2021

Identification of PiZ gene products in liver tissue by a monoclonal antibody specific for the Z mutant of alpha 1-antitrypsin

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7 January 2021

Effect of the Z mutation on the physical and inhibitory properties of alpha 1-antitrypsin

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7 January 2021

Preparation and characterization of latent alpha 1-antitrypsin

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7 January 2021

Conformation of the reactive site loop of alpha 1-proteinase inhibitor probed by limited proteolysis

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7 January 2021

Serpin polymerization is prevented by a hydrogen bond network that is centered on his-334 and stabilized by glycerol

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7 January 2021

Detection of Pi Z phenotype individuals by alpha-1-antitrypsin (AAT) immunohistochemistry in paraffin-embedded liver tissue specimens

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7 January 2021

A Kinetic Mechanism for the Polymerization of α1-Antitrypsin

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7 January 2021

Monoclonal antibody specific for the mutant PiZ alpha 1-antitrypsin and its application in an ELISA procedure for identification of PiZ gene carriers

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7 January 2021

Chronic 'cryptogenic' liver disease and malignant hepatoma in intermediate alpha 1-antitrypsin deficiency identified by a Pi Z-specific monoclonal antibody

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7 January 2021

Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function

1 reference

7 January 2021

Identifiers

DOI

10.1002/HEP.20451

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20 June 2017

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