Antiobesity pharmacotherapy: new drugs and emerging targets (Q30354242)

22 September 2017

Antiobesity pharmacotherapy: new drugs and emerging targets (English)

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22 September 2017

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4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105257%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

G W Kim

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105257%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

J E Lin

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105257%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

E S Blomain

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105257%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

language of work or name

English

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publication date

8 October 2013

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Clinical Pharmacology & Therapeutics

22 September 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105257%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

95

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105257%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

53-66

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105257%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105257%20AND%20SRC:MED&resulttype=core&format=json

New obesity agents: lorcaserin and phentermine/topiramate

1 June 2020

cites work

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3 June 2018

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New advances in models and strategies for developing anti-obesity drugs

3 June 2018

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Increased cGMP promotes healthy expansion and browning of white adipose tissue

3 June 2018

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Global obesity: trends, risk factors and policy implications

3 June 2018

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Unraveling the brain regulation of appetite: lessons from genetics

3 June 2018

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Deciphering a neuronal circuit that mediates appetite

3 June 2018

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GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity

3 June 2018

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Serotonin activates overall feeding by activating two separate neural pathways in Caenorhabditis elegans

3 June 2018

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Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study

3 June 2018

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Serotonergic anti-obesity agents: past experience and future prospects

3 June 2018

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Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP)

3 June 2018

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From PDE3B to the regulation of energy homeostasis

3 June 2018

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Health and economic burden of the projected obesity trends in the USA and the UK.

3 June 2018

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A uroguanylin-GUCY2C endocrine axis regulates feeding in mice

3 June 2018

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The genetics of brown adipose tissue

3 June 2018

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Multicenter, placebo-controlled trial of lorcaserin for weight management

3 June 2018

1 reference

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A meta-analysis of placebo-controlled clinical trials assessing the efficacy and safety of incretin-based medications in patients with type 2 diabetes

3 June 2018

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New central targets for the treatment of obesity

3 June 2018

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The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.

3 June 2018

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Uncoupling protein-1 (UCP1) contributes to the basal proton conductance of brown adipose tissue mitochondria.

3 June 2018

1 reference

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Enhanced weight loss with pramlintide/metreleptin: an integrated neurohormonal approach to obesity pharmacotherapy

3 June 2018

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Identification and importance of brown adipose tissue in adult humans

3 June 2018

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5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis

3 June 2018

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Overview of glucagon-like peptide-1 analogs and dipeptidyl peptidase-4 inhibitors for type 2 diabetes.

3 June 2018

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AMPK and PPARdelta agonists are exercise mimetics

3 June 2018

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Leptin responsiveness restored by amylin agonism in diet-induced obesity: evidence from nonclinical and clinical studies

3 June 2018

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Dipeptidyl peptidase IV inhibitors in diabetes: more than inhibition of glucagon-like peptide-1 metabolism?

3 June 2018

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Targeting melanocortin receptors: an approach to treat weight disorders and sexual dysfunction

3 June 2018

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5-HT receptor regulation of neurotransmitter release

3 June 2018

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Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.

3 June 2018

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Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity

3 June 2018

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Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysis

3 June 2018

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NO mobilizes intracellular Zn2+ via cGMP/PKG signaling pathway and prevents mitochondrial oxidant damage in cardiomyocytes

3 June 2018

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Bariatric surgery for morbid obesity

3 June 2018

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Adipose tissue-derived factors: impact on health and disease

3 June 2018

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The biology of incretin hormones

3 June 2018

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Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

3 June 2018

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Monogenic obesity in humans

3 June 2018

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AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

3 June 2018

1 reference

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Functional and pharmacological characterization of the natriuretic peptide-dependent lipolytic pathway in human fat cells

3 June 2018

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Inhibition of food intake in obese subjects by peptide YY3-36

3 June 2018

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Characterization of the effects of pancreatic polypeptide in the regulation of energy balance

3 June 2018

1 reference

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Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide.

3 June 2018

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Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids

3 June 2018

1 reference

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Phenylpropanolamine and the risk of hemorrhagic stroke

3 June 2018

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Influence of topiramate in the regulation of energy balance

3 June 2018

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Guanylyl cyclases and signaling by cyclic GMP.

3 June 2018

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Obesity as a medical problem

3 June 2018

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Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: a randomized controlled trial

3 June 2018

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Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans

3 June 2018

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Valvular heart disease associated with fenfluramine-phentermine

3 June 2018

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Congenital leptin deficiency is associated with severe early-onset obesity in humans

3 June 2018

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3 June 2018

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Structural diversity of receptors for neuropeptide Y, peptide YY and pancreatic polypeptide

3 June 2018

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A role for glucagon-like peptide-1 in the central regulation of feeding

3 June 2018

1 reference

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Molecular physiology of amylin

3 June 2018

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3 June 2018

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The role of cyclic AMP in the control of carbohydrate metabolism

21 January 2018

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Pharmacokinetics of pancreatic polypeptide in man

3 June 2018

1 reference

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Insulin, Glucagon, and Somatostatin Secretion in the Regulation of Metabolism

3 June 2018

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Rimonabant for prevention of cardiovascular events (CRESCENDO): a randomised, multicentre, placebo-controlled trial

3 June 2018

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Activation of central melanocortin pathways by fenfluramine

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Enhanced aggressive behavior in mice lacking 5-HT1B receptor.

21 January 2018

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Drug management of obesity--efficacy versus safety

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Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM-DM study.

21 January 2018

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21 January 2018

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A randomized double-blind placebo-controlled study of the long-term efficacy and safety of topiramate in the treatment of obese subjects

21 January 2018

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Topiramate: long-term maintenance of weight loss induced by a low-calorie diet in obese subjects

21 January 2018

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A 6-month randomized, placebo-controlled, dose-ranging trial of topiramate for weight loss in obesity

21 January 2018

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Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial.

21 January 2018

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Topiramate-induced weight loss is possibly due to the blockade of conditioned and automatic processes.

21 January 2018

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Potent and selective agonism of the melanocortin receptor 4 with MK-0493 does not induce weight loss in obese human subjects: energy intake predicts lack of weight loss efficacy

21 January 2018

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Neuropeptide Y5 receptor antagonism does not induce clinically meaningful weight loss in overweight and obese adults

21 January 2018

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Rational design of a combination medication for the treatment of obesity

21 January 2018

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Effect of pramlintide on A1C and body weight in insulin-treated African Americans and Hispanics with type 2 diabetes: a pooled post hoc analysis

21 January 2018

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Endoplasmic reticulum stress plays a central role in development of leptin resistance

21 January 2018

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Repeated intracerebroventricular administration of glucagon-like peptide-1-(7-36) amide or exendin-(9-39) alters body weight in the rat.

21 January 2018

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Effect of noninsulin antidiabetic drugs added to metformin therapy on glycemic control, weight gain, and hypoglycemia in type 2 diabetes

21 January 2018

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Serotonin Reciprocally Regulates Melanocortin Neurons to Modulate Food Intake

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Addiction potential of phentermine prescribed during long-term treatment of obesity.

21 January 2018

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Protein kinase G controls brown fat cell differentiation and mitochondrial biogenesis

26 November 2018

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Prandial subcutaneous injections of glucagon-like peptide-1 cause weight loss in obese human subjects.

26 November 2018

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A peripheral and an intrinsic enzyme constitute the cyclic AMP phosphodiesterase activity of rat liver plasma membranes

26 November 2018

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Hit to lead SAR study on benzoxazole derivatives for an NPY Y5 antagonist

26 November 2018

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12 December 2020

Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21

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12 December 2020

Topiramate for the treatment of binge eating disorder associated with obesity: a placebo-controlled study

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12 December 2020

The anorectic effect of a chronic peripheral infusion of amylin is abolished in area postrema/nucleus of the solitary tract (AP/NTS) lesioned rats

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12 December 2020

A neural protection racket: AMPK and the GABA(B) receptor

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12 December 2020

The effects of topiramate and sex hormones on energy balance of male and female rats

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12 December 2020

Linaclotide approved for constipation-predominant IBS

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12 December 2020

Surgery or medical therapy for obese patients with type 2 diabetes?

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12 December 2020

Topiramate reduces energy and fat gains in lean (Fa/?) and obese (fa/fa) Zucker rats

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12 December 2020

Mortality rate in patients receiving "diet pills"

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12 December 2020

Amylin concentrations and glucose control

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12 December 2020

Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction

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7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/CLPT.2013.204

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105257%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105257%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24105257%20AND%20SRC:MED&resulttype=core&format=json