In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization. (Q30380900)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26713880%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization (English)

1 reference

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3 March 2020

0 references

1 reference

Leishmania donovani

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4

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3 March 2020

T M Freeman

5

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3 March 2020

James A. Cotton

6

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Christopher J R Illingworth

3 March 2020

12

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3 March 2020

author name string

C D Shaw

1

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3 March 2020

J Lonchamp

2

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3 March 2020

T Downing

3

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3 March 2020

M Sanders

7

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3 March 2020

G Blackburn

8

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3 March 2020

J C Dujardin

9

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3 March 2020

S Rijal

10

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3 March 2020

B Khanal

11

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3 March 2020

G H Coombs

13

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3 March 2020

K C Carter

14

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3 March 2020

language of work or name

English

0 references

publication date

9 February 2016

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3 March 2020

published in

Molecular Microbiology

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3 March 2020

volume

99

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3 March 2020

page(s)

1134-1148

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3 March 2020

issue

6

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Experimental resistance to drug combinations in Leishmania donovani: metabolic and phenotypic adaptations.

3 March 2020

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Failure of miltefosine in visceral leishmaniasis is associated with low drug exposure

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Increasing failure of miltefosine in the treatment of Kala-azar in Nepal and the potential role of parasite drug resistance, reinfection, or noncompliance

20 June 2018

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Antimony-resistant but not antimony-sensitive Leishmania donovani up-regulates host IL-10 to overexpress multidrug-resistant protein 1.

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Drug susceptibility in Leishmania isolates following miltefosine treatment in cases of visceral leishmaniasis and post kala-azar dermal leishmaniasis

20 June 2018

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Multiple mutations in heterogeneous miltefosine-resistant Leishmania major population as determined by whole genome sequencing

20 June 2018

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Identification of phospholipid species affected by miltefosine action in Leishmania donovani cultures using LC-ELSD, LC-ESI/MS, and multivariate data analysis

20 June 2018

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Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Sodium stibogluconate resistance in Leishmania donovani correlates with greater tolerance to macrophage antileishmanial responses and trivalent antimony therapy

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Phospholipid translocation and miltefosine potency require both L. donovani miltefosine transporter and the new protein LdRos3 in Leishmania parasites.

21 January 2018

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21 January 2018

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Comparative transcript expression analysis of miltefosine-sensitive and miltefosine-resistant Leishmania donovani

21 January 2018

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Efficacy of miltefosine in the treatment of visceral leishmaniasis in India after a decade of use

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26713880

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/MMI.13291

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26713880%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26713880%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26713880%20AND%20SRC:MED&resulttype=core&format=json