A FAK-Cas-Rac-lamellipodin signaling module transduces extracellular matrix stiffness into mechanosensitive cell cycling. (Q30407809)

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20 March 2020

title

A FAK-Cas-Rac-lamellipodin signaling module transduces extracellular matrix stiffness into mechanosensitive cell cycling (English)

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20 March 2020

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1

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20 March 2020

author name string

Keeley L Mui

2

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20 March 2020

Bernadette Y Hsu

3

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20 March 2020

Shu-Lin Liu

4

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20 March 2020

Alexandra Cretu

5

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20 March 2020

Ziba Razinia

6

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20 March 2020

Tina Xu

7

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Ellen Puré

8

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20 March 2020

Richard K Assoian

9

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publication date

17 June 2014

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20 March 2020

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20 March 2020

volume

7

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issue

330

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page(s)

ra57

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Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo

20 March 2020

cites work

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Dynamic molecular processes mediate cellular mechanotransduction

20 June 2018

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20 June 2018

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Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells

20 June 2018

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Studying the Effects of Matrix Stiffness on Cellular Function using Acrylamide-based Hydrogels

20 June 2018

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Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

20 June 2018

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Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

20 June 2018

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A nucleator arms race: cellular control of actin assembly

20 June 2018

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Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK-ERK linkage

20 June 2018

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20 June 2018

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A tense situation: forcing tumour progression

20 June 2018

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Loss of profilin-1 expression enhances breast cancer cell motility by Ena/VASP proteins

20 June 2018

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Drosophila pico and its mammalian ortholog lamellipodin activate serum response factor and promote cell proliferation

20 June 2018

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Joint requirement for Rac and ERK activities underlies the mid-G1 phase induction of cyclin D1 and S phase entry in both epithelial and mesenchymal cells

20 June 2018

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G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility.

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin

20 June 2018

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20 June 2018

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20 June 2018

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Focal adhesions: a nexus for intracellular signaling and cytoskeletal dynamics

20 June 2018

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Effects of jasplakinolide on the kinetics of actin polymerization. An explanation for certain in vivo observations

20 June 2018

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Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway

20 June 2018

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20 June 2018

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Activation of Rac1 by a Crk SH3-binding protein, DOCK180

20 June 2018

1 reference

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Rho GTPases and the actin cytoskeleton

20 June 2018

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Cell locomotion and focal adhesions are regulated by substrate flexibility

20 June 2018

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Rho GTPases and signaling networks

20 June 2018

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An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase

20 June 2018

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

20 June 2018

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Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

20 June 2018

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Regulation of differentiated properties and proliferation of arterial smooth muscle cells.

20 June 2018

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

20 June 2018

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Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly

20 June 2018

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Regulation and localization of CAS substrate domain tyrosine phosphorylation

20 June 2018

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Crossref

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2004838

Phenotypic modulation of smooth muscle cells after arterial injury is associated with changes in the distribution of laminin and fibronectin

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24939893

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCISIGNAL.2004838

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939893%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939893%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

24939893

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24939893%20AND%20SRC:MED&resulttype=core&format=json