In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization (Q30409620)

22 September 2017

In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization (English)

1 reference

22 September 2017

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Anthony P Ford

1

1 reference

22 September 2017

18 November 2011

1 reference

22 September 2017

Purinergic Signalling

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22 September 2017

8

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22 September 2017

Suppl 1

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22 September 2017

3-26

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Targeting peripheral afferent nerve terminals for cough and dyspnea

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Contribution of nerve growth factor to upregulation of P2X₃ expression in DRG neurons of rats with femoral artery occlusion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

P2 receptors and extracellular ATP: a novel homeostatic pathway in inflammation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

GDNF levels in the lower lip skin in a rat model of trigeminal neuropathic pain: implications for nonpeptidergic fiber reinnervation and parasympathetic sprouting

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Neuropathic Nav1.3-mediated sensitization to P2X activation is regulated by protein kinase C

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

ATP and P2X purinoceptors in urinary tract disorders

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Ongoing pain in the MIA model of osteoarthritis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Sensing muscle ischemia: coincident detection of acid and ATP via interplay of two ion channels.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Alteration in skeletal muscle afferents in rats with chronic heart failure

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Nociceptor sensitization in pain pathogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

A new function for ATP: activating cardiac sympathetic afferents during myocardial ischemia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Altered purinergic signaling in colorectal dorsal root ganglion neurons contributes to colorectal hypersensitivity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Purinergic receptors are involved in tooth-pulp evoked nocifensive behavior and brainstem neuronal activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Blockade of nerve sprouting and neuroma formation markedly attenuates the development of late stage cancer pain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Reduced P2x2 receptor-mediated regulation of endocochlear potential in the ageing mouse cochlea

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Exaggerated sympathetic and pressor responses to handgrip exercise in older hypertensive humans: role of the muscle metaboreflex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

P2X2/3 and P2X3 receptors contribute to the metaboreceptor component of the exercise pressor reflex

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Familial hemiplegic migraine Ca(v)2.1 channel mutation R192Q enhances ATP-gated P2X3 receptor activity of mouse sensory ganglion neurons mediating trigeminal pain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

VEGF and its receptor-2 involved in neuropathic pain transmission mediated by P2X₂(/)₃ receptor of primary sensory neurons.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

AF-353, a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Involvement of temporomandibular joint P2X3 and P2X2/3 receptors in carrageenan-induced inflammatory hyperalgesia in rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Involvement of peripheral adenosine 5'-triphosphate and P2X purinoceptor in pain-related behavior produced by orthotopic melanoma inoculation in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

ATP and the pathogenesis of COPD.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

The birth and postnatal development of purinergic signalling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Endogenous purinergic control of bladder activity via presynaptic P2X3 and P2X2/3 receptors in the spinal cord.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Eccentric muscle contraction and stretching evoke mechanical hyperalgesia and modulate CGRP and P2X(3) expression in a functionally relevant manner

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

P2X purinergic receptor ligands: recently patented compounds

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Targeted ablation of cardiac sympathetic neurons reduces the susceptibility to ischemia-induced sustained ventricular tachycardia in conscious rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

P2X(1) and P2X(3) purinergic receptors differentially modulate the inflammatory response in human osteoarthritic synovial fibroblasts

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Discovery and optimization of RO-85, a novel drug-like, potent, and selective P2X3 receptor antagonist

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Plasma ATP concentration and venous oxygen content in the forearm during dynamic handgrip exercise

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Purinergic mechanosensory transduction and visceral pain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Double P2X2/P2X3 purinergic receptor knockout mice do not taste NaCl or the artificial sweetener SC45647.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Visceral organ cross-sensitization - an integrated perspective

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Purinergic receptors and pain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Coding of pleasant touch by unmyelinated afferents in humans

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Purinergic signaling in special senses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

ATP release by cardiac myocytes in a simulated ischaemia model: inhibition by a connexin mimetic and enhancement by an antiarrhythmic peptide

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Functional up-regulation of P2X 3 receptors in the chronically compressed dorsal root ganglion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

P2X2 receptors differentiate placodal vs. neural crest C-fiber phenotypes innervating guinea pig lungs and esophagus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Increased level of extracellular ATP at tumor sites: in vivo imaging with plasma membrane luciferase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Homomeric and heteromeric P2X3 receptors in peripheral sensory neurons.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Selective P2X(7) receptor antagonists for chronic inflammation and pain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Molecular mechanisms of sensitization of pain-transducing P2X3 receptors by the migraine mediators CGRP and NGF.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Purinergic mechanism in the immune system: A signal of danger for dendritic cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Cutaneous sensory neurons expressing the Mrgprd receptor sense extracellular ATP and are putative nociceptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Botulinum toxin type A normalizes alterations in urothelial ATP and NO release induced by chronic spinal cord injury

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Evaluation of purinergic mechanism for the treatment of voiding dysfunction: a study in conscious spinal cord-injured rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Intravenous ATP infusions can be safely administered in the home setting: a study in pre-terminal cancer patients

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Molecular probes for P2X7 receptor studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Neural upregulation in interstitial cystitis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Localization of P2X2 and P2X3 receptors in rat trigeminal ganglion neurons.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Receptor activated bladder and spinal ATP release in neurally intact and chronic spinal cord injured rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Mechanical allodynia and thermal hyperalgesia induced by experimental squamous cell carcinoma of the lower gingiva in rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Purinergic signalling--an overview

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Investigation into the role of P2X(3)/P2X(2/3) receptors in neuropathic pain following chronic constriction injury in the rat: an electrophysiological study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Purinoceptors as therapeutic targets for lower urinary tract dysfunction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Antinociceptive properties of a non-nucleotide P2X3/P2X2/3 receptor antagonist

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

ATP signaling is crucial for communication from taste buds to gustatory nerves

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

The mammalian exercise pressor reflex in health and disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

P2X2 knockout mice and P2X2/P2X3 double knockout mice reveal a role for the P2X2 receptor subunit in mediating multiple sensory effects of ATP

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Re-organization of P2X3 receptor localization on epidermal nerve fibers in a murine model of cancer pain.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Electrophysiological-anatomic correlates of ATP-triggered vagal reflex in the dog. V. Role of purinergic receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

siRNA relieves chronic neuropathic pain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

What activates visceral afferents?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

The liberation of adenosine triphosphate on antidromic stimulation of sensory nerves

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Activation of purinergic receptor subtypes modulates odor sensitivity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Contributions of P2X3 homomeric and heteromeric channels to acute and chronic pain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Experimental muscle pain and tenderness following infusion of endogenous substances in humans

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Analgesic profile of intrathecal P2X(3) antisense oligonucleotide treatment in chronic inflammatory and neuropathic pain states in rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

P2X3 knock-out mice reveal a major sensory role for urothelially released ATP

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

P2X receptors in peripheral neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Differential regulation of P2X(3) mRNA expression by peripheral nerve injury in intact and injured neurons in the rat sensory ganglia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Modulation of BzATP and formalin induced nociception: attenuation by the P2X receptor antagonist, TNP-ATP and enhancement by the P2X(3) allosteric modulator, cibacron blue

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

ATP in human skin elicits a dose-related pain response which is potentiated under conditions of hyperalgesia.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Release of vasoactive substances from endothelial cells by shear stress and purinergic mechanosensory transduction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

In vivo pathway of thermal hyperalgesia by intrathecal administration of alpha,beta-methylene ATP in mouse spinal cord: involvement of the glutamate-NMDA receptor system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

The expression of P2X3 purinoreceptors in sensory neurons: effects of axotomy and glial-derived neurotrophic factor.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

P2X receptor-mediated excitation of nociceptive afferents in the normal and arthritic rat knee joint

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Immunohistochemical study of the P2X2 and P2X3 receptor subunits in rat and monkey sensory neurons and their central terminals.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

ATP-stimulated release of ATP by human endothelial cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Mechanism of action of ATP on canine pulmonary vagal C fibre nerve terminals.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Synergistic effect of acute hypoxia on flow-induced release of ATP from cultured endothelial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

A P2X purinoceptor expressed by a subset of sensory neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Antagonism by aspirin and fenamates of bronchoconstriction and nociception induced by adenosine-5'-triphosphate.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Extracellular ATP: effects, sources and fate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Identification of algogenic substances in human erythrocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Observations on the algogenic actions of adenosine compounds on the human blister base preparation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Purine-mediated signalling in pain and visceral perception

20 June 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Depletion of substance P from rat primary sensory neurons by ATP, an implication of P2X receptor-mediated release of substance P.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Distinct roles of P2X receptors in modulating glutamate release at different primary sensory synapses in rat spinal cord

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Up-regulation of P2X3 receptor during stretch of bladder urothelial cells from patients with interstitial cystitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

On the immunohistochemical distribution of ionotropic P2X receptors in the nucleus tractus solitarius of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

ATP responses in human C nociceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Effects of A‐317491, a novel and selective P2X3/P2X2/3 receptor antagonist, on neuropathic, inflammatory and chemogenic nociception following intrathecal and intraplantar administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Pharmacological characterization of P2X1 and P2X3 purinergic receptors in bovine chondrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Peripheral mechanisms underlying the essential role of P2X3,2/3 receptors in the development of inflammatory hyperalgesia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Correlation of changes in pain intensity with synovial fluid adenosine triphosphate levels after treatment of patients with osteoarthritis of the knee with high-molecular-weight hyaluronic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Capsaicin receptor VR1 and ATP-gated ion channel P2X3 in human urinary bladder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Novel capsaicin (VR1) and purinergic (P2X3) receptors in Hirschsprung's intestine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

P2X3-immunoreactive nerve fibres in neurogenic detrusor overactivity and the effect of intravesical resiniferatoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Bladder and cutaneous sensory neurons of the rat express different functional P2X receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Activation and sensitisation of low and high threshold afferent fibres mediated by P2X receptors in the mouse urinary bladder

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Activation of ureter nociceptors by exogenous and endogenous ATP in guinea pig.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Botulinum toxin A inhibits ATP release from bladder urothelium after chronic spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Therapeutic effects of the putative P2X3/P2X2/3 antagonist A-317491 on cyclophosphamide-induced cystitis in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Purinergic contribution to small intestinal afferent hypersensitivity in a murine model of postinfectious bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Immunocytochemical localization of P2X3 purinoceptors in sensory neurons in naive rats and following neuropathic injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Effect of sodium ferulate on the hyperalgesia mediated by P2X3 receptor in the neuropathic pain rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Cyclooxygenase inhibitors suppress the expression of P2X(3) receptors in the DRG and attenuate hyperalgesia following chronic constriction injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Sensory purinergic receptor P2X3 is elevated in burning mouth syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Alteration of dorsal root ganglion P2X3 receptor expression and function following spinal nerve ligation in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

P2X(3) expression is not altered by lingual nerve injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Adrenergic regulation of P2X3 and TRPV1 receptors: differential effects of spared nerve injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Involvement of P2X receptor subtypes in ATP-induced enhancement of the cough reflex sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Involvement of ionotropic purinergic receptors in the histamine-induced enhancement of the cough reflex sensitivity in guinea pigs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Effects of aerosolized adenosine 5'-triphosphate vs adenosine 5'-monophosphate on dyspnea and airway caliber in healthy nonsmokers and patients with asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Extracellular adenosine triphosphate and chronic obstructive pulmonary disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Topographically distinct epidermal nociceptive circuits revealed by axonal tracers targeted to Mrgprd

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Reduced C-afferent fibre density affects perceived pleasantness and empathy for touch.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Effect of puerarin on P2X3 receptor involved in hyperalgesia after burn injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Effect of tetramethylpyrazine on DRG neuron P2X3 receptor involved in transmitting pain after burn.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Developmental regulation of neuron-specific P2X3 receptor expression in the rat cochlea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Developmentally regulated expression of the P2X3 receptor in the mouse cochlea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

P2X receptor signaling inhibits BDNF-mediated spiral ganglion neuron development in the neonatal rat cochlea

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Expression of adenosine triphosphate P2X3 receptors in rat molar pulp and trigeminal ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

The co-expression of P2X3 receptor with VR1 and VRL-1 in the rat trigeminal ganglion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Trigeminal P2X3 receptor expression differs from dorsal root ganglion and is modulated by deep tissue inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Behavioural responses and expression of P2X3 receptor in trigeminal ganglion after experimental tooth movement in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Mechanisms mediating the enhanced gene transcription of P2X3 receptor by calcitonin gene-related peptide in trigeminal sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Expressions of P2X2 and P2X3 receptors in rat nodose neurons after myocardial ischemia injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Myocardial ischemic nociceptive signaling mediated by P2X3 receptor in rat stellate ganglion neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Role of P2X3 receptor in myocardial ischemia injury and nociceptive sensory transmission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Increased sympathoexcitatory reflex induced by myocardial ischemic nociceptive signaling via P2X2/3 receptor in rat superior cervical ganglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Effect of P2 receptor blockade with pyridoxine on sympathetic response to exercise pressor reflex in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X(3)/P2X(2/3) antagonist for the treatment of pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Identification and SAR of novel diaminopyrimidines. Part 2: The discovery of RO-51, a potent and selective, dual P2X(3)/P2X(2/3) antagonist for the treatment of pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

P2X3 receptor mediates heat hyperalgesia in a rat model of trigeminal neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

Clinical evaluation of the efficacy of the P2X7purinergic receptor antagonist AZD9056 on the signs and symptoms of rheumatoid arthritis in patients with active disease despite treatment with methotrexate or sulphasalazine

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Functional downregulation of P2X3 receptor subunit in rat sensory neurons reveals a significant role in chronic neuropathic and inflammatory pain.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

ATP P2X receptor-mediated enhancement of glutamate release and evoked EPSCs in dorsal horn neurons of the rat spinal cord.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265711

Activation of ATP P2X receptors elicits glutamate release from sensory neuron synapses

26 November 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

The P2X7receptor as a therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11302-011-9271-6

P2X3 is expressed by DRG neurons that terminate in inner lamina II

21 January 2018

1 reference

12 December 2020

ATP P2X receptors mediate fast synaptic transmission in the dorsal horn of the rat spinal cord

1 reference

12 December 2020

Inorganic pyrophosphate generation from adenosine triphosphate by cell-free human synovial fluid

1 reference

12 December 2020

Airway nerves and dyspnea associated with inflammatory airway disease

1 reference

12 December 2020

Neutralization of nerve growth factor induces plasticity of ATP-sensitive P2X3 receptors of nociceptive trigeminal ganglion neurons

1 reference

12 December 2020

Mechanisms underlying enhanced P2X receptor-mediated responses in the neuropathic pain state

1 reference

12 December 2020

Delayed reinnervation by nonpeptidergic nociceptive afferents of the glabrous skin of the rat hindpaw in a neuropathic pain model

1 reference

12 December 2020

Intraepithelial vagal sensory nerve terminals in rat pulmonary neuroepithelial bodies express P2X(3) receptors

1 reference

12 December 2020

Neuronal expression of P2X3 purinoceptors in the rat retina

1 reference

12 December 2020

Exercise with angina and cramp?

1 reference

12 December 2020

Effect of lappaconitine on neuropathic pain mediated by P2X3 receptor in rat dorsal root ganglion

1 reference

12 December 2020

Distribution of immunoreactivity for P2X3, P2X5, and P2X6-purinoceptors in mouse retina

1 reference

12 December 2020

Exploration of P2X3 in the rat stellate ganglia after myocardial ischemia

1 reference

12 December 2020

Synovial fluid ATP: a potential substrate for the production of inorganic pyrophosphate

1 reference

12 December 2020

P2X purinoceptor-mediated excitation of trigeminal lingual nerve terminals in an in vitro intra-arterially perfused rat tongue preparation

1 reference

12 December 2020

Delayed upregulation of ATP P2X3 receptors of trigeminal sensory neurons by calcitonin gene-related peptide

1 reference

12 December 2020

Local release of ATP into the arterial inflow and venous drainage of human skeletal muscle: insight from ATP determination with the intravascular microdialysis technique

1 reference

12 December 2020

Distribution of P2X3 receptors in the rat trigeminal ganglion after inferior alveolar nerve injury

1 reference

12 December 2020

P2X receptors-mediated cytosolic phospholipase A2 activation in primary afferent sensory neurons contributes to neuropathic pain

1 reference

12 December 2020

10.1007/S11302-011-9271-6

Identifiers

DOI

1 reference

Dimensions Publication ID

22 September 2017

1017536593

0 references

Fatcat ID

release_26y242l3affbzj6dykfblhkghe

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/26y242l3affbzj6dykfblhkghe

24 November 2022

mapped directly with Wikidata item

1 reference

22 September 2017

PubMed publication ID

22095157

1 reference