A putative molecular-activation switch in the transmembrane domain of erbB2. (Q30476898)

14 September 2017

A putative molecular-activation switch in the transmembrane domain of erbB2. (English)

1 reference

14 September 2017

transmembrane protein

0 references

Sarel J Fleishman

1

0 references

Nir Ben-Tal

object named as

Nir Ben-Tal

series ordinal

3

0 references

Joseph Schlessinger

series ordinal

2

object named as

Joseph Schlessinger

1 reference

PMCID

138543

14 September 2017

language of work or name

English

0 references

publication date

2 December 2002

1 reference

Proceedings of the National Academy of Sciences of the United States of America

14 September 2017

1 reference

14 September 2017

99

1 reference

14 September 2017

25

1 reference

14 September 2017

15937-15940

1 reference

Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

Cell signaling by receptor tyrosine kinases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

Rotational coupling of the transmembrane and kinase domains of the Neu receptor tyrosine kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

The GxxxG motif: a framework for transmembrane helix-helix association

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

Receptor signaling: when dimerization is not enough

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

A transmembrane helix dimer: structure and implications

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

Dimerization of the p185neu transmembrane domain is necessary but not sufficient for transformation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

ErbB-2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

Helix to helix packing in proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

Different structural alterations upregulate in vitro tyrosine kinase activity and transforming potency of the erbB-2 gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

A point mutation in the neu oncogene mimics ligand induction of receptor aggregation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

A sequence motif in the transmembrane region of growth factor receptors with tyrosine kinase activity mediates dimerization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

Signal transduction by receptors with tyrosine kinase activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

G to A polymorphism at amino acid codon 655 of the human erbB-2/HER2 gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

Glycophorin A dimerization is driven by specific interactions between transmembrane alpha-helices

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

A subdomain in the transmembrane domain is necessary for p185neu* activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

Statistical analysis of amino acid patterns in transmembrane helices: the GxxxG motif occurs frequently and in association with beta-branched residues at neighboring positions.

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252640799

The single transmembrane domains of ErbB receptors self-associate in cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252640799

An EcoRI polymorphism at the insulin receptor locus on a fragment comprising exons 4 to 8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252640799

Population-based, case-control study of HER2 genetic polymorphism and breast cancer risk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252640799

A Novel Scoring Function for Predicting the Conformations of Tightly Packed Pairs of Transmembrane α-Helices

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252640799

Strong hydrogen bonding interactions involving a buried glutamic acid in the transmembrane sequence of the neu/erbB-2 receptor

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=138543

Neu receptor dimerization

26 November 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.252640799

21 January 2018

Identifiers

DOI

10.1073/PNAS.252640799

1 reference

14 September 2017

0 references

1 reference

14 September 2017

1 reference

PMCID

138543