Nucleation-dependent tau filament formation: the importance of dimerization and an estimation of elementary rate constants (Q30481896)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18359772%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Nucleation-dependent tau filament formation: the importance of dimerization and an estimation of elementary rate constants (English)

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4 January 2020

1

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4 January 2020

author name string

Sohee Kim

2

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4 January 2020

Jonathan Bonchak

3

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4 January 2020

Tanakorn Songrug

4

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4 January 2020

Anastasios Matzavinos

5

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4 January 2020

Jeff Kuret

6

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4 January 2020

language of work or name

English

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publication date

21 March 2008

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Journal of Biological Chemistry

4 January 2020

published in

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4 January 2020

volume

283

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4 January 2020

issue

20

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4 January 2020

page(s)

13806-13816

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Detection and quantification of tau aggregation using a membrane filter assay

4 January 2020

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Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins

20 June 2018

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20 June 2018

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Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology

20 June 2018

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Evidence for two distinct binding sites for tau on microtubules

20 June 2018

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20 June 2018

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Tau paired helical filaments from Alzheimer's disease brain and assembled in vitro are based on beta-structure in the core domain

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Thermodynamics and kinetics of actin filament nucleation.

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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The regulatory Ser262 of microtubule-associated protein tau is phosphorylated by phosphorylase kinase

20 June 2018

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The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology.

20 June 2018

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Kinetics of self-assembling microtubules: an "inverse problem" in biochemistry.

20 June 2018

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Levels of normal and abnormally phosphorylated tau in different cellular and regional compartments of Alzheimer disease and control brains.

20 June 2018

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Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filaments

20 June 2018

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Cooperative polymerization reactions. Analytical approximations, numerical examples, and experimental strategy

20 June 2018

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Alzheimer's disease: paired helical filaments and cytomembranes

20 June 2018

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20 June 2018

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Subunit structure of paired helical filaments in Alzheimer's disease

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Ligand-dependent tau filament formation: implications for Alzheimer's disease progression.

20 June 2018

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Tau conformational changes correspond to impairments of episodic memory in mild cognitive impairment and Alzheimer's disease.

21 January 2018

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Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans.

21 January 2018

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Anionic Micelles and Vesicles Induce Tau Fibrillization in Vitro

21 January 2018

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Analysis of protein aggregation kinetics.

21 January 2018

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Transthyretin aggregation under partially denaturing conditions is a downhill polymerization

21 January 2018

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Triggers of full-length tau aggregation: a role for partially folded intermediates.

21 January 2018

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Congo red populates partially unfolded states of an amyloidogenic protein to enhance aggregation and amyloid fibril formation

21 January 2018

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Electron microscopy as a quantitative method for investigating tau fibrillization

21 January 2018

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Cyanine dye N744 inhibits tau fibrillization by blocking filament extension: implications for the treatment of tauopathic neurodegenerative diseases

21 January 2018

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The core of tau-paired helical filaments studied by scanning transmission electron microscopy and limited proteolysis.

21 January 2018

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Initiation and Synergistic Fibrillization of Tau and Alpha-Synuclein

21 January 2018

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Site-specific pseudophosphorylation modulates the rate of tau filament dissociation

21 January 2018

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Nonsaturable binding indicates clustering of tau on the microtubule surface in a paired helical filament-like conformation.

21 January 2018

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Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

21 January 2018

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Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding.

21 January 2018

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Defining Cdk5 ligand chemical space with small molecule inhibitors of tau phosphorylation.

21 January 2018

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Toward a unified scheme for the aggregation of tau into Alzheimer paired helical filaments

21 January 2018

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Site-specific nitration and oxidative dityrosine bridging of the tau protein by peroxynitrite: implications for Alzheimer's disease

21 January 2018

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Accumulation of pathological tau species and memory loss in a conditional model of tauopathy.

21 January 2018

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Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology

21 January 2018

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Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

21 January 2018

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Sequence of neurofibrillary changes in aging and Alzheimer's disease: A confocal study with phospho-tau antibody, AD2.

21 January 2018

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Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

26 November 2018

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Dynamics of linear protein polymer disassembly.

26 November 2018

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Length distributions of hemoglobin S fibers

26 November 2018

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12 December 2020

Polymerization of tau into filaments in the presence of heparin: the minimal sequence required for tau-tau interaction

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12 December 2020

Nucleation-elongation: a mechanism for cooperative supramolecular polymerization

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12 December 2020

Structure, microtubule interactions, and paired helical filament aggregation by tau mutants of frontotemporal dementias

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12 December 2020

Identifiers

DOI

10.1074/JBC.M800247200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18359772%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18359772%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference