Incomplete restoration of Mpl expression in the mpl-/- mouse produces partial correction of the stem cell-repopulating defect and paradoxical thrombocytosis (Q30486155)

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English	Incomplete restoration of Mpl expression in the mpl-/- mouse produces partial correction of the stem cell-repopulating defect and paradoxical thrombocytosis	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Incomplete restoration of Mpl expression in the mpl-/- mouse produces partial correction of the stem cell-repopulating defect and paradoxical thrombocytosis (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

author name string

Brian J Lannutti

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Angela Epp

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Jacqueline Roy

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Junmei Chen

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Neil C Josephson

5

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

0 references

publication date

16 September 2008

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

113

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

1778-1785

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Enrichment of hematopoietic stem cells with SLAM and LSK markers for the detection of hematopoietic stem cell function in normal and Trp53 null mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Signals emanating from the membrane proximal region of the thrombopoietin receptor (mpl) support hematopoietic stem cell self-renewal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Lineage-specific hematopoietic growth factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

The thrombopoietin receptor, c-Mpl, is a selective surface marker for human hematopoietic stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

MPL mutations in 23 patients suffering from congenital amegakaryocytic thrombocytopenia: the type of mutation predicts the course of the disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

The Mpl receptor expressed on endothelial cells does not contribute significantly to the regulation of circulating thrombopoietin levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

The molecular mechanisms that control thrombopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Congenital amegakaryocytic thrombocytopenia in three siblings: molecular analysis of atypical clinical presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Mpl Baltimore: a thrombopoietin receptor polymorphism associated with thrombocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Synergistic effects on erythropoiesis, thrombopoiesis, and stem cell competitiveness in mice deficient in thrombopoietin and steel factor receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Evidence that the number of hematopoietic stem cells per animal is conserved in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Human plasma thrombopoietin levels are regulated by binding to platelet thrombopoietin receptors in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

c-mpl mutations are the cause of congenital amegakaryocytic thrombocytopenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Identification of mutations in the c-mpl gene in congenital amegakaryocytic thrombocytopenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Familial essential thrombocythemia associated with one-base deletion in the 5'-untranslated region of the thrombopoietin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Role of c-mpl in early hematopoiesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Serum thrombopoietin levels in patients correlate inversely with platelet counts during chemotherapy-induced thrombocytopenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Thrombopoietin signal transduction in purified murine megakaryocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Serum thrombopoietin (TPO) levels in patients with amegakaryocytic thrombocytopenia are much higher than those with immune thrombocytopenic purpura.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Ectopic expression of murine TPO receptor (c-mpl) in mice is pathogenic and induces erythroblastic proliferation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Deficiencies in progenitor cells of multiple hematopoietic lineages and defective megakaryocytopoiesis in mice lacking the thrombopoietic receptor c-Mpl

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Thrombopoietin in thrombocytopenic mice: evidence against regulation at the mRNA level and for a direct regulatory role of platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Primitive hemopoietic stem cells: direct assay of most productive populations by competitive repopulation with simple binomial, correlation and covariance calculations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Thrombocytopenia in c-mpl-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

The reciprocal relationship of thrombopoietin (c-Mpl ligand) to changes in the platelet mass during busulfan-induced thrombocytopenia in the rabbit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

20 June 2018

Critical Role of Thrombopoietin in Maintaining Adult Quiescent Hematopoietic Stem Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

26 November 2018

Increased megakaryocytopoiesis in Lyn-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

26 November 2018

Identification and activation of Src family kinases in primary megakaryocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

26 November 2018

Observation of Antigen-Dependent CD8+ T-Cell/ Dendritic Cell Interactions in Vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

26 November 2018

Murine hematopoietic stem cell characterization and its regulation in BM transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

26 November 2018

Thrombopoietin does not induce lineage-restricted commitment of Mpl-R expressing pluripotent progenitors but permits their complete erythroid and megakaryocytic differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2647669

26 November 2018

The Mpl receptor is expressed in the megakaryocytic lineage from late progenitors to platelets

1 reference

https://pubmed.ncbi.nlm.nih.gov/18796624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18796624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombocytosis in preterm infants: a possible involvement of thrombopoietin receptor gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18796624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the kinetics of TPO uptake during platelet transfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/18796624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of thrombopoietin with the platelet c-mpl receptor in plasma: binding, internalization, stability and pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/18796624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/18796624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectopic overexpression of c-mpl by retroviral-mediated gene transfer suppressed megakaryopoiesis but enhanced erythropoiesis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18796624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Familial essential thrombocythemia: clinical characteristics of 11 cases in one family

1 reference

https://pubmed.ncbi.nlm.nih.gov/18796624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A 2-kb c-mpl promoter fragment is sufficient to direct expression to the megakaryocytic lineage and sites of embryonic hematopoiesis in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18796624

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1182/BLOOD-2007-11-124859

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https://api.fatcat.wiki/v0/release/7amuvu6ubfdr3eeeqku5knxdpy

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