Increased megakaryocytopoiesis in Lyn-deficient mice (Q46898187)

26 December 2017

title

Increased megakaryocytopoiesis in Lyn-deficient mice (English)

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26 December 2017

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Lannutti BJ

1

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26 December 2017

Minear J

series ordinal

2

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26 December 2017

Blake N

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3

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26 December 2017

Drachman JG

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4

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26 December 2017

language of work or name

English

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publication date

16 January 2006

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26 December 2017

published in

Oncogene

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26 December 2017

volume

25

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26 December 2017

issue

23

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26 December 2017

page(s)

3316-3324

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26 December 2017

The inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Lyn-deficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Sequential activation of protein kinase C (PKC)-alpha and PKC-epsilon contributes to sustained Raf/ERK1/2 activation in endothelial cells under mechanical strain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Granulocyte colony-stimulating factor receptor signaling involves the formation of a three-component complex with Lyn and Syk protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Dissecting the thrombopoietin receptor: functional elements of the Mpl cytoplasmic domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Thrombopoietin signal transduction requires functional JAK2, not TYK2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Src family protein tyrosine kinases and cellular signal transduction pathways

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Thrombopoietin potentiates the protein-kinase-C-mediated activation of mitogen-activated protein kinase/ERK kinases and extracellular signal-regulated kinases in human platelets

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Requirement for mitogen-activated protein kinase activation in the response of embryonic stem cell-derived hematopoietic cells to thrombopoietin in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Src family kinases are required for prolactin induction of cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Activation of SHIP by NADPH oxidase-stimulated Lyn leads to enhanced apoptosis in neutrophils

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Src-family kinases in B-cell development and signaling

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Phosphatidylinositol 3-kinase is necessary but not sufficient for thrombopoietin-induced proliferation in engineered Mpl-bearing cell lines as well as in primary megakaryocytic progenitors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Thrombopoietin: a pan-hematopoietic cytokine

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Gain- and loss-of-function Lyn mutant mice define a critical inhibitory role for Lyn in the myeloid lineage

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

The Src kinase Lyn is a negative regulator of mast cell proliferation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Dysregulated FcepsilonRI signaling and altered Fyn and SHIP activities in Lyn-deficient mast cells.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunity

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3beta signaling and leads to an increased transit time through the G1 phase of the cell cycle

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Raf-1 is not required for megakaryocytopoiesis or TPO-induced ERK phosphorylation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Akt-dependent cytokine production in mast cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Induction of polyploidization in leukemic cell lines and primary bone marrow by Src kinase inhibitor SU6656.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Lyn tyrosine kinase regulates thrombopoietin-induced proliferation of hematopoietic cell lines and primary megakaryocytic progenitors

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Identification and activation of Src family kinases in primary megakaryocytes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

SHIP1 and Lyn Kinase Negatively Regulate Integrin alpha IIb beta 3 signaling in platelets.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Thrombopoietin induces phosphoinositol 3-kinase activation through SHP2, Gab, and insulin receptor substrate proteins in BAF3 cells and primary murine megakaryocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

The Lyn tyrosine kinase negatively regulates neutrophil integrin signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Sustained activation of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway is required for megakaryocytic differentiation of K562 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

The roles of phosphatidylinositol 3-kinase and protein kinase Czeta for thrombopoietin-induced mitogen-activated protein kinase activation in primary murine megakaryocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Control of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

The many faces of Src: multiple functions of a prototypical tyrosine kinase

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Inhibition of the B cell by CD22: a requirement for Lyn

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Lyn tyrosine kinase is important for IL-5-stimulated eosinophil differentiation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Cellular functions regulated by Src family kinases

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209351

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209351

1 reference

26 December 2017

Dimensions Publication ID

1024954579

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1 reference

26 December 2017