Mutant huntingtin impairs vesicle formation from recycling endosomes by interfering with Rab11 activity (Q30491414)

17 October 2017

Mutant huntingtin impairs vesicle formation from recycling endosomes by interfering with Rab11 activity (English)

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17 October 2017

Xueyi Li

1

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17 October 2017

Clive Standley

2

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17 October 2017

Ellen Sapp

3

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17 October 2017

Antonio Valencia

4

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17 October 2017

Zheng-Hong Qin

5

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17 October 2017

Kimberly B Kegel

6

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17 October 2017

Jennifer Yoder

7

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17 October 2017

Laryssa A Comer-Tierney

8

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17 October 2017

Miguel Esteves

9

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17 October 2017

Kathryn Chase

10

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17 October 2017

Jonathan Alexander

11

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17 October 2017

Nicholas Masso

12

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17 October 2017

Lindsay Sobin

13

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17 October 2017

Karl Bellve

14

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17 October 2017

Richard Tuft

15

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17 October 2017

Lawrence Lifshitz

16

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17 October 2017

Kevin Fogarty

17

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17 October 2017

Neil Aronin

18

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17 October 2017

Marian DiFiglia

19

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17 October 2017

language of work or name

English

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publication date

14 September 2009

1 reference

Molecular and Cellular Biology

17 October 2017

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17 October 2017

29

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17 October 2017

22

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17 October 2017

6106-6116

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describes a project that uses

17 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2772576/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus

1 reference

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The microtubule-binding protein CLIP-170 coordinates mDia1 and actin reorganization during CR3-mediated phagocytosis

20 June 2018

1 reference

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Interaction between tumor suppressor adenomatous polyposis coli and topoisomerase IIalpha: implication for the G2/M transition

20 June 2018

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Fluorescence imaging of membrane dynamics

20 June 2018

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Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease

20 June 2018

1 reference

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Unsolved mysteries in membrane traffic

20 June 2018

1 reference

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A guided tour into subcellular colocalization analysis in light microscopy

20 June 2018

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Microtubule motors at the intersection of trafficking and transport

20 June 2018

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Rabs and their effectors: achieving specificity in membrane traffic

20 June 2018

1 reference

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Increased apoptosis, Huntingtin inclusions and altered differentiation in muscle cell cultures from Huntington's disease subjects

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Direct interaction with Rab11a targets the epithelial Ca2+ channels TRPV5 and TRPV6 to the plasma membrane

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons

20 June 2018

1 reference

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Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro

20 June 2018

1 reference

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Controlling the location and activation of Rab GTPases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Intracellular trafficking of bile salt export pump (ABCB11) in polarized hepatic cells: constitutive cycling between the canalicular membrane and rab11-positive endosomes

20 June 2018

1 reference

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20 June 2018

1 reference

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Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

The mechanisms of vesicle budding and fusion

20 June 2018

1 reference

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Actin cytoskeleton remodeling during early Drosophila furrow formation requires recycling endosomal components Nuclear-fallout and Rab11

20 June 2018

1 reference

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Aberrant A2A receptor function in peripheral blood cells in Huntington's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

The hunt for huntingtin function: interaction partners tell many different stories

20 June 2018

1 reference

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Modulation of cellular cholesterol transport and homeostasis by Rab11.

20 June 2018

1 reference

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Rab proteins as membrane organizers

20 June 2018

1 reference

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FIP-2, a coiled-coil protein, links Huntingtin to Rab8 and modulates cellular morphogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Rab11 regulates the compartmentalization of early endosomes required for efficient transport from early endosomes to the trans-golgi network

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Dynamin:GTP controls the formation of constricted coated pits, the rate limiting step in clathrin-mediated endocytosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

The receptor recycling pathway contains two distinct populations of early endosomes with different sorting functions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Identification of regulators for Ypt1 GTPase nucleotide cycling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Hydrolysis of GTP on rab11 is required for the direct delivery of transferrin from the pericentriolar recycling compartment to the cell surface but not from sorting endosomes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

ARF6 targets recycling vesicles to the plasma membrane: insights from an ultrastructural investigation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Interaction of huntingtin-associated protein with dynactin P150Glued

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Rab11 is associated with transferrin-containing recycling compartments in K562 cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Rab11 regulates recycling through the pericentriolar recycling endosome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Basolateral to apical transcytosis in polarized cells is indirect and involves BFA and trimeric G protein sensitive passage through the apical endosome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

In migrating fibroblasts, recycling receptors are concentrated in narrow tubules in the pericentriolar area, and then routed to the plasma membrane of the leading lamella

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

A quantitative analysis of the endocytic pathway in baby hamster kidney cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

A function of huntingtin in guanine nucleotide exchange on Rab11.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Evidence of apoptosis and mitochondrial abnormalities in peripheral blood cells of Huntington's disease patients.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Constitutive endocytosis and recycling of the neuronal glutamate transporter, excitatory amino acid carrier 1.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Mutant huntingtin inhibits clathrin-independent endocytosis and causes accumulation of cholesterol in vitro and in vivo

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Oxidative stress in skin fibroblasts cultures of patients with Huntington's disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Plasma membrane domains specialized for clathrin-mediated endocytosis in primary cells

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Generalized brain and skin proteasome inhibition in Huntington's disease

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

Huntingtin expression stimulates endosomal-lysosomal activity, endosome tubulation, and autophagy.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2772576

The transcytotic pathway of an apical plasma membrane protein (B10) in hepatocytes is similar to that of IgA and occurs via a tubular pericentriolar compartment

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19752198

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.00420-09

1 reference

17 October 2017

1 reference

17 October 2017

1 reference