Age-related hearing loss in C57BL/6J mice is mediated by Bak-dependent mitochondrial apoptosis. (Q30491795)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19901338%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Age-related hearing loss in C57BL/6J mice is mediated by Bak-dependent mitochondrial apoptosis (English)

1 reference

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12 February 2020

1 reference

1 reference

7

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10

Masaru Tanokura

1 reference

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12 February 2020

6

Tatsuya Yamasoba

1 reference

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12 February 2020

8

Richard Weindruch

1 reference

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12 February 2020

11

Tomas A Prolla

1 reference

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12 February 2020

Christiaan Leeuwenburgh

9

object named as

Christiaan Leeuwenburgh

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12 February 2020

author name string

Shinichi Someya

1

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12 February 2020

Jinze Xu

2

1 reference

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12 February 2020

Kenji Kondo

3

1 reference

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12 February 2020

Dalian Ding

4

1 reference

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12 February 2020

Richard J Salvi

5

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12 February 2020

language of work or name

English

0 references

publication date

9 November 2009

1 reference

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Proceedings of the National Academy of Sciences of the United States of America

12 February 2020

published in

1 reference

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12 February 2020

volume

106

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12 February 2020

page(s)

19432-19437

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12 February 2020

issue

46

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19901338%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

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Molecular regulation of DNA damage-induced apoptosis in neurons of cerebral cortex

20 June 2018

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Iron accumulation with age, oxidative stress and functional decline

20 June 2018

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20 June 2018

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20 June 2018

1 reference

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Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins.

20 June 2018

1 reference

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20 June 2018

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The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase gamma

20 June 2018

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Oxidative imbalance in the aging inner ear.

20 June 2018

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Role of mitochondrial dysfunction and mitochondrial DNA mutations in age-related hearing loss

20 June 2018

1 reference

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Contributions of mouse models to understanding of age- and noise-related hearing loss

20 June 2018

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A method to determine RNA and DNA oxidation simultaneously by HPLC-ECD: greater RNA than DNA oxidation in rat liver after doxorubicin administration

20 June 2018

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The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations

20 June 2018

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A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

20 June 2018

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Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

20 June 2018

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Extension of murine life span by overexpression of catalase targeted to mitochondria

20 June 2018

1 reference

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p53 in neuronal apoptosis

20 June 2018

1 reference

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In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation

20 June 2018

1 reference

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Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

20 June 2018

1 reference

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Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2780799

20 June 2018

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20 June 2018

Mitochondrial deafness

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Association of cadherin 23 with polygenic inheritance and genetic modification of sensorineural hearing loss

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2780799

p53 has a direct apoptogenic role at the mitochondria

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2780799

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

20 June 2018

1 reference

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Maternally inherited hearing impairment

20 June 2018

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Effects of dietary restriction and antioxidants on presbyacusis

20 June 2018

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Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses

20 June 2018

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Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease.

20 June 2018

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20 June 2018

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20 June 2018

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Temporal bone analysis of patients with presbycusis reveals high frequency of mitochondrial mutations.

20 June 2018

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Aging and the auditory brainstem response in mice with severe or minimal presbycusis.

20 June 2018

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Dietary restriction and presbyacusis: periods of restriction and auditory threshold losses in the CBA/J mouse

20 June 2018

1 reference

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20 June 2018

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Caloric restriction suppresses apoptotic cell death in the mammalian cochlea and leads to prevention of presbycusis.

21 January 2018

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Paraquat neurotoxicity is mediated by a Bak-dependent mechanism.

21 January 2018

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21 January 2018

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Therapeutic potential of N-acetylcysteine in age-related mitochondrial neurodegenerative diseases

21 January 2018

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Developmental and aging changes of Bak expression in the human brain.

21 January 2018

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A major gene affecting age-related hearing loss is common to at least ten inbred strains of mice.

21 January 2018

1 reference

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Cochlear damage due to germanium-induced mitochondrial dysfunction in guinea pigs

21 January 2018

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Genes encoding mitochondrial respiratory chain components are profoundly down-regulated with aging in the cochlea of DBA/2J mice.

21 January 2018

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Cell death after co-administration of cisplatin and ethacrynic acid.

21 January 2018

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Calpain inhibitors protect auditory sensory cells from hypoxia and neurotrophin-withdrawal induced apoptosis.

21 January 2018

1 reference

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Mutations at position 7445 in the precursor of mitochondrial tRNA(Ser(UCN)) gene in three maternal Chinese pedigrees with sensorineural hearing loss.

21 January 2018

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Sensory neuroprotection, mitochondrial preservation, and therapeutic potential of N-acetyl-cysteine after nerve injury

26 November 2018

1 reference

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26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19901338

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Paraquat-induced hair cell damage and protection with the superoxide dismutase mimetic m40403.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19901338

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0908786106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19901338%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19901338%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference