Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation. (Q30495320)

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English	Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation.	scientific article

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1 February 2020

Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation (English)

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Xiao Lei Chen

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Alok Tomar

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Nichol L G Miller

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Jiyeon Yoo

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David D Schlaepfer

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4 May 2010

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Journal of Biological Chemistry

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21526-21536

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1 February 2020

Cellular functions of FAK kinases: insight into molecular mechanisms and novel functions

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Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation

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Autophosphorylation-independent and -dependent functions of focal adhesion kinase during development

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Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility

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Paxillin comes of age

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PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility

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Cellular characterization of a novel focal adhesion kinase inhibitor

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Focal adhesion kinase modulates tension signaling to control actin and focal adhesion dynamics

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p130Cas: a versatile scaffold in signaling networks

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Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness

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20 June 2018

p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain

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Negative regulation of FAK signaling by SOCS proteins

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12 December 2020

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Overexpression of focal adhesion kinase in vascular endothelial cells promotes angiogenesis in transgenic mice

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Identifiers

10.1074/JBC.M110.129999

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1 February 2020

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