The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response. (Q30497188)

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14 February 2020

title

The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response (English)

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14 February 2020

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6

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14 February 2020

Jan Ellenberg

7

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14 February 2020

Thomas Küntziger

10

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14 February 2020

author name string

Helga B Landsverk

1

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14 February 2020

Felipe Mora-Bermúdez

2

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14 February 2020

Ole J B Landsverk

3

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14 February 2020

Grete Hasvold

4

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14 February 2020

Soheil Naderi

5

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14 February 2020

Philippe Collas

8

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14 February 2020

Randi G Syljuåsen

9

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14 February 2020

publication date

1 October 2010

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14 February 2020

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14 February 2020

volume

11

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14 February 2020

issue

11

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14 February 2020

page(s)

868-875

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Repo-man controls a protein phosphatase 1-dependent threshold for DNA damage checkpoint activation

14 February 2020

cites work

1 reference

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The DNA-damage response in human biology and disease

20 June 2018

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Mitotic phosphatases: from entry guards to exit guides

20 June 2018

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Phosphatase inhibition and cell survival after DNA damage induced by radiation

20 June 2018

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TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs

20 June 2018

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Reduced expression of PNUTS leads to activation of Rb-phosphatase and caspase-mediated apoptosis

20 June 2018

1 reference

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A novel ATM-dependent pathway regulates protein phosphatase 1 in response to DNA damage

20 June 2018

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Emerging roles of nuclear protein phosphatases

20 June 2018

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Protein phosphatase 1 nuclear targeting subunit is a hypoxia inducible gene: its role in post-translational modification of p53 and MDM2.

20 June 2018

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Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4

20 June 2018

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Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

20 June 2018

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Repo-Man recruits PP1 gamma to chromatin and is essential for cell viability

20 June 2018

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Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells

20 June 2018

1 reference

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PNUTS enhances in vitro chromosome decondensation in a PP1-dependent manner

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966950

Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis.

20 June 2018

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The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

20 June 2018

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cAMP-mediated inhibition of DNA replication and S phase progression: involvement of Rb, p21Cip1, and PCNA.

20 June 2018

1 reference

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Distinct functions of condensin I and II in mitotic chromosome assembly

20 June 2018

1 reference

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Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1.

20 June 2018

1 reference

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PNUTS, a protein phosphatase 1 (PP1) nuclear targeting subunit. Characterization of its PP1- and RNA-binding domains and regulation by phosphorylation

20 June 2018

1 reference

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Time-lapse imaging reveals dynamic relocalization of PP1gamma throughout the mammalian cell cycle

20 June 2018

1 reference

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PNUTS (phosphatase nuclear targeting subunit) inhibits retinoblastoma-directed PP1 activity

20 June 2018

1 reference

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Re-staging mitosis: a contemporary view of mitotic progression

20 June 2018

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p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

20 June 2018

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Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint

20 June 2018

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Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit

20 June 2018

1 reference

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Purification and characterisation of p99, a nuclear modulator of protein phosphatase 1 activity

20 June 2018

1 reference

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HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response.

20 June 2018

1 reference

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Interactor-mediated nuclear translocation and retention of protein phosphatase-1.

21 January 2018

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Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems

21 January 2018

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Photobleaching of GFP-labeled H2AX in chromatin: H2AX has low diffusional mobility in the nucleus.

21 January 2018

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Resisting arrest: recovery from checkpoint arrest through dephosphorylation of Chk1 by PP1.

21 January 2018

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Subunit structure and regulation of protein phosphatase-1 in rat liver nuclei

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20890310

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nuclear organisation of NIPP1, a regulatory subunit of protein phosphatase 1 that associates with pre-mRNA splicing factors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20890310

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dephosphorylation of Rb (Thr-821) in response to cell stress

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20890310

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOR.2010.134

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20890310%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20890310%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

PubMed publication ID

20890310

1 reference