Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer (Q30497879)

12 October 2017

Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer (English)

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alternative mRNA splicing, via spliceosome

12 October 2017

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1 reference

Ming Sound Tsao

6

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Benjamin J. Blencowe

7

object named as

Benjamin J Blencowe

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12 October 2017

Christine M Misquitta-Ali

1

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12 October 2017

Edith Cheng

2

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12 October 2017

Dave O'Hanlon

3

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12 October 2017

Ni Liu

4

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12 October 2017

C Jane McGlade

5

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12 October 2017

language of work or name

English

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publication date

1 November 2010

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Molecular and Cellular Biology

12 October 2017

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12 October 2017

31

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12 October 2017

1

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12 October 2017

138-150

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describes a project that uses

12 October 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3019846/fullTextXML

inferred from PubMed Central ID database lookup

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The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism

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HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

20 June 2018

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20 June 2018

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The multiple functions of Numb

20 June 2018

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The pathobiology of splicing

20 June 2018

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Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model

20 June 2018

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Regulation of vertebrate nervous system alternative splicing and development by an SR-related protein

20 June 2018

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Wnt/Planar cell polarity signaling: a new paradigm for cancer therapy

20 June 2018

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The links between transcription, beta-catenin/JNK signaling, and carcinogenesis

20 June 2018

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Current-generation high-throughput sequencing: deepening insights into mammalian transcriptomes

20 June 2018

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Alternative splicing in lung cancer

20 June 2018

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Lung cancer biology: a genetic and genomic perspective.

20 June 2018

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Cancer-associated regulation of alternative splicing

20 June 2018

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20 June 2018

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RNA-Seq: a revolutionary tool for transcriptomics

20 June 2018

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Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

20 June 2018

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Alternative isoform regulation in human tissue transcriptomes

20 June 2018

1 reference

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Gene expression subtraction of non-cancerous lung from smokers and non-smokers with adenocarcinoma, as a predictor for smokers developing lung cancer

20 June 2018

1 reference

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Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites

20 June 2018

1 reference

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Evidence for a role of the amyloid precursor protein in thyroid carcinogenesis

20 June 2018

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Global analysis of alternative splicing differences between humans and chimpanzees

20 June 2018

1 reference

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Inhibition of angiogenesis in the treatment of non-small cell lung cancer

20 June 2018

1 reference

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Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis

20 June 2018

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Alternative splicing: new insights from global analyses

20 June 2018

1 reference

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The role of microtubule actin cross-linking factor 1 (MACF1) in the Wnt signaling pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

Profiling alternatively spliced mRNA isoforms for prostate cancer classification

20 June 2018

1 reference

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Unbalanced alternative splicing and its significance in cancer

20 June 2018

1 reference

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Quantitative microarray profiling provides evidence against widespread coupling of alternative splicing with nonsense-mediated mRNA decay to control gene expression

20 June 2018

1 reference

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The amyloid precursor protein and postnatal neurogenesis/neuroregeneration

20 June 2018

1 reference

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Inferring global levels of alternative splicing isoforms using a generative model of microarray data

20 June 2018

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Microtubule actin crosslinking factor 1b: a novel plakin that localizes to the Golgi complex

20 June 2018

1 reference

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Inhibition of angiogenesis and tumor growth by beta and gamma-secretase inhibitors

20 June 2018

1 reference

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Revealing global regulatory features of mammalian alternative splicing using a quantitative microarray platform

20 June 2018

1 reference

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Detecting tissue-specific regulation of alternative splicing as a qualitative change in microarray data

20 June 2018

1 reference

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Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

20 June 2018

1 reference

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Increased expression of amyloid precursor protein in oral squamous cell carcinoma

20 June 2018

1 reference

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Increased expression and processing of the Alzheimer amyloid precursor protein in pancreatic cancer may influence cellular proliferation

20 June 2018

1 reference

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Optimization of oligonucleotide arrays and RNA amplification protocols for analysis of transcript structure and alternative splicing

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

Involvement of numb in vertebrate retinal development: evidence for multiple roles of numb in neural differentiation and maturation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

Alternative splicing: multiple control mechanisms and involvement in human disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

Angiogenesis correlates with vascular endothelial growth factor expression but not with Ki-ras oncogene activation in non-small cell lung carcinoma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

A coactivator of pre-mRNA splicing

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

The alternatively spliced Kunitz protease inhibitor domain alters amyloid beta protein precursor processing and amyloid beta protein production in cultured cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

Amyloid precursor protein is a primary androgen target gene that promotes prostate cancer growth.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

Multiple alternative splicing markers for ovarian cancer

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

A switch in numb isoforms is a critical step in cortical development.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

The alternative splicing of tau exon 10 and its regulatory proteins CLK2 and TRA2-BETA1 changes in sporadic Alzheimer's disease

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

Distinct expression patterns of splicing isoforms of mNumb in the endocrine lineage of developing pancreas.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3019846

The heparin-binding domain confers diverse functions of VEGF-A in development and disease: a structure-function study

26 November 2018

1 reference

12 December 2020

Vascular endothelial growth factor 189 mRNA isoform expression specifically correlates with tumor angiogenesis, patient survival, and postoperative relapse in non-small-cell lung cancer

1 reference

12 December 2020

Identification of alternative splicing markers for breast cancer

1 reference

12 December 2020

Quantitative real-time reverse transcription PCR study of the expression of vascular endothelial growth factor (VEGF) splice variants and VEGF receptors (VEGFR-1 and VEGFR-2) in non small cell lung cancer

1 reference

12 December 2020

The binding of vascular endothelial growth factor to its receptors is dependent on cell surface-associated heparin-like molecules

1 reference

12 December 2020

Identification of cis-acting elements involved in an alternative splicing of the amyloid precursor protein (APP) gene

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.00709-10

1 reference

12 October 2017

1 reference

12 October 2017

1 reference