Retinyl ester storage particles (retinosomes) from the retinal pigmented epithelium resemble lipid droplets in other tissues (Q30500125)

19 October 2017

Retinyl ester storage particles (retinosomes) from the retinal pigmented epithelium resemble lipid droplets in other tissues (English)

1 reference

19 October 2017

3

Krzysztof Palczewski

1 reference

19 October 2017

2

Grazyna Palczewska

1 reference

19 October 2017

1

Tivadar Orban

1 reference

19 October 2017

PMCID

3089567

language of work or name

English

0 references

publication date

25 March 2011

1 reference

Journal of Biological Chemistry

19 October 2017

1 reference

19 October 2017

286

1 reference

19 October 2017

19

1 reference

19 October 2017

17248-17258

1 reference

PMCID

3089567

describes a project that uses

19 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3089567/fullTextXML

inferred from PubMed Central ID database lookup

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20 June 2018

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The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria

20 June 2018

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STRING 8--a global view on proteins and their functional interactions in 630 organisms

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Impact of retinal disease-associated RPE65 mutations on retinoid isomerization

20 June 2018

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Quantitative label-free imaging of lipid composition and packing of individual cellular lipid droplets using multiplex CARS microscopy

20 June 2018

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Retinyl ester homeostasis in the adipose differentiation-related protein-deficient retina

20 June 2018

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The molecular basis of retinoid absorption: a genetic dissection

20 June 2018

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Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina

20 June 2018

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Imaging of lipid biosynthesis: how a neutral lipid enters lipid droplets

20 June 2018

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A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum

20 June 2018

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Rab-regulated interaction of early endosomes with lipid droplets

20 June 2018

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Delivery of retinoid-based therapies to target tissues

20 June 2018

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Lipidomics reveals that adiposomes store ether lipids and mediate phospholipid traffic

20 June 2018

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Heat shock protein 70 is translocated to lipid droplets in rat adipocytes upon heat stimulation

20 June 2018

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20 June 2018

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Topology and membrane association of lecithin: retinol acyltransferase.

20 June 2018

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Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents

20 June 2018

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G protein-coupled receptor rhodopsin

20 June 2018

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An intimate collaboration between peroxisomes and lipid bodies

20 June 2018

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Aberrant metabolites in mouse models of congenital blinding diseases: formation and storage of retinyl esters.

20 June 2018

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Lipid droplets: a unified view of a dynamic organelle

20 June 2018

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Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis.

20 June 2018

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Lecithin:retinol acyltransferase is responsible for amidation of retinylamine, a potent inhibitor of the retinoid cycle

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

RPE65 is the isomerohydrolase in the retinoid visual cycle

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Retinosomes: new insights into intracellular managing of hydrophobic substances in lipid bodies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Noninvasive two-photon imaging reveals retinyl ester storage structures in the eye

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Lecithin-retinol acyltransferase is essential for accumulation of all-trans-retinyl esters in the eye and in the liver.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Rpe65 Is a Retinyl Ester Binding Protein That Presents Insoluble Substrate to the Isomerase in Retinal Pigment Epithelial Cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Dynamic and regulated association of caveolin with lipid bodies: modulation of lipid body motility and function by a dominant negative mutant

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

The surface of lipid droplets is a phospholipid monolayer with a unique Fatty Acid composition

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Recovery of visual functions in a mouse model of Leber congenital amaurosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Lipid droplets: proteins floating on a pool of fat.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Confronting complexity: the interlink of phototransduction and retinoid metabolism in the vertebrate retina

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

TIP47 associates with lipid droplets

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Esterification of all-trans-retinol in normal human epithelial cell strains and carcinoma lines from oral cavity, skin and breast: reduced expression of lecithin:retinol acyltransferase in carcinoma lines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Sterol carrier protein-2 alters high density lipoprotein-mediated cholesterol efflux

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Rapid restoration of visual pigment and function with oral retinoid in a mouse model of childhood blindness

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

On the control of lipolysis in adipocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

High-performance liquid chromatography and laser desorption/ionization mass spectrometry of retinyl esters

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

ARPE-19, a human retinal pigment epithelial cell line with differentiated properties

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

The retinal pigment epithelium: a versatile partner in vision.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Morphological characterization of the cholesteryl ester cycle in cultured mouse macrophage foam cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Structure-function relationships in the adipose cell. I. Ultrastructure of the isolated adipose cell

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

A novel fluorescent fatty acid, 5-methyl-BDY-3-dodecanoic acid, is a potential probe in lipid transport studies by incorporating selectively to lipid classes of BHK cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Retinyl esters are the substrate for isomerohydrolase.

20 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.195198

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.195198

The lipid-droplet proteome reveals that droplets are a protein-storage depot.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.195198

Lipids partition caveolin-1 from ER membranes into lipid droplets: updating the model of lipid droplet biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.195198

Mammary glands of adipophilin-null mice produce an amino-terminally truncated form of adipophilin that mediates milk lipid droplet formation and secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.195198

Perilipin A increases triacylglycerol storage by decreasing the rate of triacylglycerol hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.195198

Living cells as test tubes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.195198

Disruption of the vimentin intermediate filament system during adipose conversion of 3T3-L1 cells inhibits lipid droplet accumulation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089567

Membrane-bound lipid particles from beef heart. Chemical composition and structure

26 November 2018

1 reference

12 December 2020

Composition and morphology of lipid droplets from oviduct epithelial cells

1 reference

12 December 2020

Uptake, processing and release of retinoids by cultured human retinal pigment epithelium

1 reference

12 December 2020

CoA- and non-CoA-dependent retinol esterification in retinal pigment epithelium

1 reference

12 December 2020

Proteomics reveal a link between the endoplasmic reticulum and lipid secretory mechanisms in mammary epithelial cells

1 reference

12 December 2020

Effects of dietary retinoid and triglyceride on the lipid composition of rat liver stellate cells and stellate cell lipid droplets

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.195198

1 reference

19 October 2017

1 reference

19 October 2017

1 reference

PMCID

3089567