Oxidized LDL/CD36 interaction induces loss of cell polarity and inhibits macrophage locomotion (Q30524150)

12 August 2017

Oxidized LDL/CD36 interaction induces loss of cell polarity and inhibits macrophage locomotion (English)

1 reference

12 August 2017

Young Mi Park

1

1 reference

12 August 2017

Judith A Drazba

2

1 reference

12 August 2017

Amit Vasanji

3

1 reference

12 August 2017

Thomas Egelhoff

4

1 reference

12 August 2017

Maria Febbraio

5

1 reference

12 August 2017

Roy L Silverstein

6

1 reference

12 August 2017

20 June 2012

1 reference

Molecular Biology of the Cell

12 August 2017

1 reference

12 August 2017

23

1 reference

12 August 2017

16

1 reference

12 August 2017

3057-3068

1 reference

describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3418302/fullTextXML

inferred from PubMed Central ID database lookup

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Vav family Rho guanine nucleotide exchange factors regulate CD36-mediated macrophage foam cell formation

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CD36 modulates migration of mouse and human macrophages in response to oxidized LDL and may contribute to macrophage trapping in the arterial intima

20 June 2018

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PDZRhoGEF and myosin II localize RhoA activity to the back of polarizing neutrophil-like cells

20 June 2018

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Absence of CD36 protects against atherosclerosis in ApoE knock-out mice with no additional protection provided by absence of scavenger receptor A I/II

20 June 2018

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Separate but not equal: differential mechanical roles for Myosin isoforms

20 June 2018

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Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells

20 June 2018

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Big roles for small GTPases in the control of directed cell movement

20 June 2018

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A CD36-dependent signaling cascade is necessary for macrophage foam cell formation

20 June 2018

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Nonmuscle myosin IIA-dependent force inhibits cell spreading and drives F-actin flow

20 June 2018

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A Rac switch regulates random versus directionally persistent cell migration

20 June 2018

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Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss

20 June 2018

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Inhibiting myosin light chain kinase induces apoptosis in vitro and in vivo

20 June 2018

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A local coupling model and compass parameter for eukaryotic chemotaxis.

20 June 2018

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Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tract

20 June 2018

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PAK and other Rho-associated kinases--effectors with surprisingly diverse mechanisms of regulation

20 June 2018

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Emigration of monocyte-derived cells from atherosclerotic lesions characterizes regressive, but not progressive, plaques

20 June 2018

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Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

20 June 2018

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Myosin phosphatase: structure, regulation and function

20 June 2018

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Role of the cytoskeleton during leukocyte responses

20 June 2018

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Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts.

20 June 2018

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Cell migration: Rho GTPases lead the way

20 June 2018

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Obesity is associated with macrophage accumulation in adipose tissue

20 June 2018

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Cell migration: integrating signals from front to back

20 June 2018

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Vav proteins, masters of the world of cytoskeleton organization.

20 June 2018

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Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase

20 June 2018

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Mechanisms of polarization of the shape of fibroblasts and epitheliocytes: Separation of the roles of microtubules and Rho-dependent actin-myosin contractility

20 June 2018

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Cell motility: can Rho GTPases and microtubules point the way?

20 June 2018

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Atherosclerosis. the road ahead

20 June 2018

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Localized Rac activation dynamics visualized in living cells

20 June 2018

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Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

20 June 2018

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Distinct roles of ROCK (Rho-kinase) and MLCK in spatial regulation of MLC phosphorylation for assembly of stress fibers and focal adhesions in 3T3 fibroblasts.

20 June 2018

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Rac1 GTPases control filopodia formation, cell motility, endocytosis, cytokinesis and development in Dictyostelium.

20 June 2018

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Role of Rac in controlling the actin cytoskeleton and chemotaxis in motile cells

20 June 2018

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Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK.

20 June 2018

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Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice

20 June 2018

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Phosphorylation of myosin light chain kinase by p21-activated kinase PAK2

20 June 2018

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Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo

20 June 2018

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Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

20 June 2018

1 reference

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Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading

20 June 2018

1 reference

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Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro

20 June 2018

1 reference

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A cell's sense of direction

20 June 2018

1 reference

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Inhibition of myosin light chain kinase by p21-activated kinase

20 June 2018

1 reference

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Rho GTPases control polarity, protrusion, and adhesion during cell movement

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Phosphorylation of non-muscle myosin II regulatory light chain by p21-activated kinase (gamma-PAK)

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Atherosclerosis — An Inflammatory Disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Mitogen-activated protein kinase pathways

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Cell migration: a physically integrated molecular process

20 June 2018

1 reference

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Oxidized LDL binds to CD36 on human monocyte-derived macrophages and transfected cell lines. Evidence implicating the lipid moiety of the lipoprotein as the binding site

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Cell polarity: an examination of its behavioral expression and its consequences for polymorphonuclear leukocyte chemotaxis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Practical methods for plasma lipoprotein analysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Phosphorylation of smooth muscle myosin at two distinct sites by myosin light chain kinase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Identification, phosphorylation, and dephosphorylation of a second site for myosin light chain kinase on the 20,000-dalton light chain of smooth muscle myosin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Smooth muscle myosin phosphatase inhibition and force enhancement by black sponge toxin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Effects of phosphorylation of light chain residues threonine 18 and serine 19 on the properties and conformation of smooth muscle myosin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Human nonmuscle myosin heavy chains are encoded by two genes located on different chromosomes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Vav GEFs regulate macrophage morphology and adhesion-induced Rac and Rho activation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Vav1 regulates the migration and adhesion of dendritic cells.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Wound healing defect of Vav3-/- mice due to impaired {beta}2-integrin-dependent macrophage phagocytosis of apoptotic neutrophils.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Chemotaxis in shallow gradients is mediated independently of PtdIns 3-kinase by biased choices between random protrusions.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced Obesity

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Azathioprine suppresses ezrin-radixin-moesin-dependent T cell-APC conjugation through inhibition of Vav guanosine exchange activity on Rac proteins

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Vav1 and Vav2 play different roles in macrophage migration and cytoskeletal organization

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Stem cell transplantation reveals that absence of macrophage CD36 is protective against atherosclerosis

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Rho-kinase inhibition and electromechanical coupling in rat and guinea-pig ureter smooth muscle: Ca2+-dependent and -independent mechanisms

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3418302

Fibrillar beta-amyloid-stimulated intracellular signaling cascades require Vav for induction of respiratory burst and phagocytosis in monocytes and microglia

26 November 2018

1 reference

12 December 2020

Continued inhibition of atherosclerotic lesion development in long term Western diet fed CD36o /apoEo mice

1 reference

12 December 2020

Sequential morphologic studies of regression of advanced atherosclerosis

1 reference

12 December 2020

RhoA inhibits the nerve growth factor-induced Rac1 activation through Rho-associated kinase-dependent pathway

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.E11-12-1051

1 reference

12 August 2017

1 reference

12 August 2017

1 reference