Photocrosslinkable pMHC monomers stain T cells specifically and cause ligand-bound TCRs to be 'preferentially' transported to the cSMAC. (Q30539566)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22660579%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

Photocrosslinkable pMHC monomers stain T cells specifically and cause ligand-bound TCRs to be 'preferentially' transported to the cSMAC (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22660579%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

1

1 reference

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3 February 2020

Evan W Newell

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22660579%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

author name string

Johannes B Huppa

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22660579%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Jun Huang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22660579%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Peter J R Ebert

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22660579%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Qi-Jing Li

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22660579%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Mark M Davis

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22660579%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

language of work or name

English

0 references

publication date

3 June 2012

1 reference

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3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22660579%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

volume

13

1 reference

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3 February 2020

page(s)

674-680

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22660579%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22660579%20AND%20SRC:MED&resulttype=core&format=json

Distinct CD4+ helper T cells involved in primary and secondary responses to infection.

3 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Interplay between T cell receptor binding kinetics and the level of cognate peptide presented by major histocompatibility complexes governs CD8+ T cell responsiveness

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Interrogating the repertoire: broadening the scope of peptide-MHC multimer analysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Human T cells expressing affinity-matured TCR display accelerated responses but fail to recognize low density of MHC-peptide antigen

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Structural Basis of Specificity and Cross-Reactivity in T Cell Receptors Specific for Cytochrome c-I-E

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

TCR-peptide-MHC interactions in situ show accelerated kinetics and increased affinity.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

T cell receptor triggering by force

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

The alphabeta T cell receptor is an anisotropic mechanosensor.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

T cell antigen receptor signaling and immunological synapse stability require myosin IIA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

The actin cytoskeleton in T cell activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

A constant affinity threshold for T cell tolerance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Empty class II major histocompatibility complex created by peptide photolysis establishes the role of DM in peptide association

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

T cells as a self-referential, sensory organ

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Regulation of T-cell activation by the cytoskeleton

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

A monovalent streptavidin with a single femtomolar biotin binding site

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

CD8+ cytotoxic T lymphocyte activation by soluble major histocompatibility complex-peptide dimers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

T cell receptor binding kinetics required for T cell activation depend on the density of cognate ligand on the antigen-presenting cell.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

The relationship of MHC-peptide binding and T cell activation probed using chemically defined MHC class II oligomers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

The immunological synapse: a molecular machine controlling T cell activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Three-dimensional segregation of supramolecular activation clusters in T cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Phenotypic analysis of antigen-specific T lymphocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

T cell receptor antagonist peptides induce positive selection

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Formation of functional peptide complexes of class II major histocompatibility complex proteins from subunits produced in Escherichia coli

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Kinetic proofreading in T-cell receptor signal transduction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Crystal structure of an H-2Kb-ovalbumin peptide complex reveals the interplay of primary and secondary anchor positions in the major histocompatibility complex binding groove

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Induction of ovalbumin-specific cytotoxic T cells by in vivo peptide immunization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

RAG-1-deficient mice have no mature B and T lymphocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex

20 June 2018

1 reference

Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton

21 January 2018

1 reference

Design and use of conditional MHC class I ligands.

21 January 2018

1 reference

T cell killing does not require the formation of a stable mature immunological synapse.

21 January 2018

1 reference

Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected]

21 January 2018

1 reference

Cutting Edge: mechanical forces acting on T cells immobilized via the TCR complex can trigger TCR signaling.

21 January 2018

1 reference

Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

21 January 2018

1 reference

The immunological synapse balances T cell receptor signaling and degradation

21 January 2018

1 reference

Tyrosine-phosphorylated T cell receptor ζ chain associates with the actin cytoskeleton upon Activation of mature T lymphocytes

21 January 2018

1 reference

Structural analysis of TCR-ligand interactions studied on H-2Kd-restricted cloned CTL specific for a photoreactive peptide derivative

21 January 2018

1 reference

Dynein-Driven Transport of T Cell Receptor Microclusters Regulates Immune Synapse Formation and T Cell Activation

21 January 2018

1 reference

The efficiency of antigen recognition by CD8+ CTL clones is determined by the frequency of serial TCR engagement.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3645478

Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22660579

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Photoaffinity labeling of the T cell receptor on cloned cytotoxic T lymphocytes by covalent photoreactive ligand

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22660579

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.2344

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22660579%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22660579%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22660579%20AND%20SRC:MED&resulttype=core&format=json