Epigenetic signature and enhancer activity of the human APOE gene. (Q30557542)

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6 March 2020

title

Epigenetic signature and enhancer activity of the human APOE gene (English)

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6 March 2020

author name string

Chang-En Yu

1

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6 March 2020

Eiron Cudaback

2

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6 March 2020

Jessica Foraker

3

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6 March 2020

Zachary Thomson

4

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6 March 2020

Lesley Leong

5

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6 March 2020

Franziska Lutz

6

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6 March 2020

James Anthony Gill

7

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6 March 2020

Aleen Saxton

8

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6 March 2020

Brian Kraemer

9

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6 March 2020

Patrick Navas

10

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6 March 2020

Lynn M Bekris

13

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6 March 2020

publication date

25 July 2013

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6 March 2020

published in

Human Molecular Genetics

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6 March 2020

volume

22

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6 March 2020

issue

24

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6 March 2020

page(s)

5036-5047

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Apolipoprotein C-I is an APOE genotype-dependent suppressor of glial activation

6 March 2020

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Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE.

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20 June 2018

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20 June 2018

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On the nature of human housekeeping genes

20 June 2018

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Screening reveals conserved and nonconserved transcriptional regulatory elements including an E3/E4 allele-dependent APOE coding region enhancer

20 June 2018

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Age-specific epigenetic drift in late-onset Alzheimer's disease

20 June 2018

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Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels.

20 June 2018

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Epigenetics: differential DNA methylation in mammalian somatic tissues

20 June 2018

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Comprehensive analysis of APOE and selected proximate markers for late-onset Alzheimer's disease: patterns of linkage disequilibrium and disease/marker association

20 June 2018

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Increased tau phosphorylation in apolipoprotein E4 transgenic mice is associated with activation of extracellular signal-regulated kinase: modulation by zinc

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

20 June 2018

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The apolipoprotein E/CI/CII gene cluster and late-onset Alzheimer disease

20 June 2018

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Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

20 June 2018

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Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Motor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury

20 June 2018

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Polymorphisms associated with cholesterol and risk of cardiovascular events

21 January 2018

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APOE genotype predicts when--not whether--one is predisposed to develop Alzheimer disease

21 January 2018

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A dual role for apolipoprotein e in neuroinflammation: anti- and pro-inflammatory activity

21 January 2018

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Impact of apolipoprotein E (ApoE) polymorphism on brain ApoE levels

21 January 2018

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ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

21 January 2018

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APOE genotype, family history of dementia, and Alzheimer disease risk: a 6-year follow-up study.

21 January 2018

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Apolipoprotein E epsilon4 association with dementia in a population-based study: The Framingham study.

21 January 2018

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Apolipoprotein E epsilon4 count affects age at onset of Alzheimer disease, but not lifetime susceptibility: The Cache County Study

21 January 2018

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Marked regional differences of brain human apolipoprotein E expression in targeted replacement mice

21 January 2018

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Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription.

21 January 2018

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Allelic expression of APOE in human brain: effects of epsilon status and promoter haplotypes

21 January 2018

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Independent association of an APOE gene promoter polymorphism with increased risk of myocardial infarction and decreased APOE plasma concentrations--the ECTIM Study

21 January 2018

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Mixed-Effects Models in Sand S-PLUS

21 January 2018

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DNA-binding factors shape the mouse methylome at distal regulatory regions

21 January 2018

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Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS.

26 November 2018

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Identification of a novel enhancer of brain expression near the apoE gene cluster by comparative genomics

26 November 2018

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26 November 2018

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12 December 2020

Distinct mechanisms control RNA polymerase II recruitment to a tissue-specific locus control region and a downstream promoter

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12 December 2020

Characterization of a unique human apolipoprotein E variant associated with type III hyperlipoproteinemia

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12 December 2020

Human apolipoprotein E. The complete amino acid sequence

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12 December 2020

Defective hepatic lipoprotein receptor binding of beta-very low density lipoproteins from type III hyperlipoproteinemic patients. Importance of apolipoprotein E

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12 December 2020

A methylated CpG island 3' in the apolipoprotein-E gene does not repress its transcription

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12 December 2020

Apolipoprotein E polymorphism, Alzheimer's disease and vascular dementia among elderly Finnish men

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12 December 2020

Targeted Replacement of the Mouse Apolipoprotein E Gene with the Common Human APOE3 Allele Enhances Diet-induced Hypercholesterolemia and Atherosclerosis

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12 December 2020

Identifiers

DOI

10.1093/HMG/DDT354

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23892237%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23892237%20AND%20SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

23892237

1 reference