TCRs with high affinity for foreign pMHC show self-reactivity (Q30873107)

27 June 2017

TCRs with high affinity for foreign pMHC show self-reactivity (English)

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27 June 2017

Phillip D Holler

1

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27 June 2017

Lukasz K Chlewicki

series ordinal

2

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27 June 2017

David M Kranz

series ordinal

3

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27 June 2017

language of work or name

English

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publication date

9 December 2002

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27 June 2017

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27 June 2017

4

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27 June 2017

1

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27 June 2017

55-62

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T-cell antigen receptor genes and T-cell recognition

27 June 2017

1 reference

7 January 2021

Selecting and maintaining a diverse T-cell repertoire

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7 January 2021

Self-tolerance and the composition of T cell repertoire

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7 January 2021

The MHC reactivity of the T cell repertoire prior to positive and negative selection.

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7 January 2021

T-cell-receptor affinity and thymocyte positive selection

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7 January 2021

Specific T cell recognition of minimally homologous peptides: evidence for multiple endogenous ligands

1 reference

7 January 2021

A very high level of crossreactivity is an essential feature of the T-cell receptor

1 reference

7 January 2021

Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen

1 reference

7 January 2021

A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex

1 reference

7 January 2021

Structure, specificity and CDR mobility of a class II restricted single-chain T-cell receptor

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7 January 2021

TCR binding to peptide-MHC stabilizes a flexible recognition interface

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7 January 2021

Thermodynamics of T cell receptor binding to peptide-MHC: evidence for a general mechanism of molecular scanning

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7 January 2021

The TCR triggering puzzle

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7 January 2021

A kinetic basis for T cell receptor repertoire selection during an immune response

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7 January 2021

A kinetic window constricts the T cell receptor repertoire in the thymus.

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7 January 2021

CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation.

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7 January 2021

In vitro evolution of a T cell receptor with high affinity for peptide/MHC.

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7 January 2021

Yeast surface display for screening combinatorial polypeptide libraries

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7 January 2021

Isolation of anti-T cell receptor scFv mutants by yeast surface display

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7 January 2021

Directed evolution of a stable scaffold for T-cell receptor engineering.

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7 January 2021

Selection of functional T cell receptor mutants from a yeast surface-display library

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7 January 2021

Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization

1 reference

7 January 2021

Structural basis of 2C TCR allorecognition of H-2Ld peptide complexes

1 reference

7 January 2021

Correlation between the number of T cell receptors required for T cell activation and TCR-ligand affinity

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7 January 2021

A strategy for the synthesis and screening of thiol-modified peptide variants recognized by T cells

1 reference

7 January 2021

Ligand recognition by alpha beta T cell receptors

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7 January 2021

Positive selection of transgenic receptor-bearing thymocytes by Kb antigen is altered by Kb mutations that involve peptide binding

1 reference

7 January 2021

Effects of complementarity determining region mutations on the affinity of an alpha/beta T cell receptor: measuring the energy associated with CD4/CD8 repertoire skewing

1 reference

7 January 2021

Role of 2CT cell receptor residues in the binding of self- and allo-major histocompatibility complexes

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7 January 2021

Specificity and degeneracy in antigen recognition: yin and yang in the immune system.

1 reference

7 January 2021

A functional hot spot for antigen recognition in a superagonist TCR/MHC complex

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7 January 2021

Structure of murine CTLA-4 and its role in modulating T cell responsiveness

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7 January 2021

Maturation of an antibody response is governed by modulations in flexibility of the antigen-combining site

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7 January 2021

Antigen-specific T-cell receptors and their reactions with complexes formed by peptides with major histocompatibility complex proteins

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7 January 2021

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

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7 January 2021

Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex

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7 January 2021

Role of the T cell receptor ligand affinity in T cell activation by bacterial superantigens

1 reference

7 January 2021

Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion

1 reference

7 January 2021

The Shaping of the T Cell Repertoire

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7 January 2021

Analysis of the expression of peptide-major histocompatibility complexes using high affinity soluble divalent T cell receptors

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7 January 2021

Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure

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7 January 2021

Differential transport requirements of HLA and H-2 class I glycoproteins

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7 January 2021

Immunoprecipitation of cell surface structures of cloned cytotoxic T lymphocytes by clone-specific antisera

1 reference

7 January 2021

Identifiers

DOI

10.1038/NI863

1 reference

release_i7km46jzevbsdgiawuxbk2xte4

27 June 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/i7km46jzevbsdgiawuxbk2xte4

24 November 2022

mapped directly with Wikidata item

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