Apoptosis and growth arrest induced by platinum compounds in U2-OS cells reflect a specific DNA damage recognition associated with a different p53-mediated response. (Q30874066)

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English	Apoptosis and growth arrest induced by platinum compounds in U2-OS cells reflect a specific DNA damage recognition associated with a different p53-mediated response.	scientific article

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15 December 2019

Apoptosis and growth arrest induced by platinum compounds in U2-OS cells reflect a specific DNA damage recognition associated with a different p53-mediated response (English)

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15 December 2019

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15 December 2019

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15 December 2019

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15 December 2019

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Supino R

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15 December 2019

Pavesi R

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15 December 2019

Caserini C

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15 December 2019

Carenini N

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15 December 2019

Righetti SC

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15 December 2019

Zunino F

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15 December 2019

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1 December 2002

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15 December 2019

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Cell Death & Differentiation

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15 December 2019

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15 December 2019

1352-1359

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15 December 2019

A novel charged trinuclear platinum complex effective against cisplatin-resistant tumours: hypersensitivity of p53-mutant human tumour xenografts

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Cancer. p53, guardian of the genome

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Surfing the p53 network

1 reference

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Cell cycle control and cancer

1 reference

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p53 and apoptosis

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Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM.

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The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53

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Regulation of p53 function and stability by phosphorylation

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Multisite phosphorylation and the integration of stress signals at p53.

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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

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DNA damage induces phosphorylation of the amino terminus of p53

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DNA damage activates p53 through a phosphorylation-acetylation cascade

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p53-dependent apoptosis or growth arrest induced by different forms of radiation in U2OS cells: p21WAF1/CIP1 repression in UV induced apoptosis

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Effects of geometric isomerism and ligand substitution in bifunctional dinuclear platinum complexes on binding properties and conformational changes in DNA.

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Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

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Activation of p53 transcriptional activity requires ATM's kinase domain and multiple N-terminal serine residues of p53.

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Cisplatinum and taxol induce different patterns of p53 phosphorylation

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Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.

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The novel trinuclear platinum complex BBR3464 induces a cellular response different from cisplatin.

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Replication protein A (RPA) binding to duplex cisplatin-damaged DNA is mediated through the generation of single-stranded DNA.

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Interactions of mammalian proteins with cisplatin-damaged DNA.

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Interaction between replication protein A and p53 is disrupted after UV damage in a DNA repair-dependent manner

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Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase

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