Mechanism of p53-dependent apoptosis induced by 3-methylcholanthrene: involvement of p53 phosphorylation and p38 MAPK. (Q43797734)

26 November 2017

title

Mechanism of p53-dependent apoptosis induced by 3-methylcholanthrene: involvement of p53 phosphorylation and p38 MAPK. (English)

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26 November 2017

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Yong-Won Kwon

1

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26 November 2017

Shugo Ueda

2

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26 November 2017

Masaya Ueno

3

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26 November 2017

Junji Yodoi

4

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26 November 2017

Hiroshi Masutani

5

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26 November 2017

language of work or name

English

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publication date

12 November 2001

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Journal of Biological Chemistry

26 November 2017

number of pages

8

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based on heuristic

inferred from page(s)

published in

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26 November 2017

volume

277

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26 November 2017

issue

3

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26 November 2017

page(s)

1837-1844

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Role of the Ah receptor and the dioxin-inducible [Ah] gene battery in toxicity, cancer, and signal transduction.

26 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Molecular mechanisms of toxicant-induced immunosuppression: role of second messengers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Modulation of gene expression and endocrine response pathways by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Thioredoxin-dependent redox regulation of p53-mediated p21 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

JNK1, JNK2 and JNK3 are p53 N-terminal serine 34 kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

p38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Identification of redox/repair protein Ref-1 as a potent activator of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Ref-1 regulates the transactivation and pro-apoptotic functions of p53 in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Effect of tumor suppressors on cell cycle-regulatory genes: RB suppresses p34cdc2 expression and normal p53 suppresses cyclin A expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Apoptosis in Daudi human B cells in response to benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Accumulation of polycyclic aromatic hydrocarbon-induced single strand breaks is attributed to slower rejoining processes by DNA polymerase inhibitor, cytosine arabinoside in CHO-K1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Demonstration by DNA fingerprint analysis of genomic instability in mouse BALB 3T3 cells during cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Carcinogenic polynuclear hydrocarbons bind to macromolecules in cultured human bronchi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

p53 tumor suppressor gene: at the crossroads of molecular carcinogenesis, molecular epidemiology, and cancer risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Osmotic shock induces G1 arrest through p53 phosphorylation at Ser33 by activated p38MAPK without phosphorylation at Ser15 and Ser20.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Hemin-induced activation of the thioredoxin gene by Nrf2. A differential regulation of the antioxidant responsive element by a switch of its binding factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Methylcholanthrene causes increased thymocyte apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Activation of the c-fos SRE through SAP-1a

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

Thioredoxin negatively regulates p38 MAP kinase activation and IL-6 production by tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105033200

21 January 2018

Identifiers

DOI

10.1074/JBC.M105033200

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26 November 2017

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