Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity (Q31015825)

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English	Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity	scientific article

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scholarly article

1 reference

Europe PubMed Central

17 October 2017

Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity (English)

1 reference

Europe PubMed Central

17 October 2017

1 reference

based on heuristic

inferred from title

Christopher R. Weber

2

1 reference

Europe PubMed Central

17 October 2017

author name string

Wentao Qi

1

1 reference

Europe PubMed Central

17 October 2017

Kaarin Wasland

3

1 reference

Europe PubMed Central

17 October 2017

Suzana D Savkovic

4

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Europe PubMed Central

17 October 2017

language of work or name

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publication date

3 June 2011

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Europe PubMed Central

17 October 2017

1 reference

Europe PubMed Central

17 October 2017

11

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Europe PubMed Central

17 October 2017

219

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Europe PubMed Central

17 October 2017

https://scigraph.springernature.com/pub.10.1186/1471-2407-11-219

0 references

Estrogen receptor-β mediates the inhibition of DLD-1 human colon adenocarcinoma cells by soy isoflavones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Genistein increases gene expression by demethylation of WNT5a promoter in colon cancer cell line SW1116.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Tumor suppressor FOXO3 mediates signals from the EGF receptor to regulate proliferation of colonic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Epigenetic control of estrogen receptor expression and tumor suppressor genes is modulated by bioactive food compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Prognostic effect of activated EGFR expression in human colon carcinomas: comparison with EGFR status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Epidermal growth factor receptor inhibitors in cancer treatment: advances, challenges and opportunities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Tumor suppressor FOXO3 participates in the regulation of intestinal inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Genistein in the presence of 17beta-estradiol inhibits proliferation of ERbeta breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

P53 negatively regulates the transcriptional activity of FOXO3a under oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Phenoxodiol, an anticancer isoflavene, induces immunomodulatory effects in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Biochemical and structural characterization of an intramolecular interaction in FOXO3a and its binding with p53

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Tumor suppressor Foxo3a is involved in the regulation of lipopolysaccharide-induced interleukin-8 in intestinal HT-29 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Genistein induces the p21WAF1/CIP1 and p16INK4a tumor suppressor genes in prostate cancer cells by epigenetic mechanisms involving active chromatin modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Implications of phytoestrogen intake for breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Preliminary studies on induction of apoptosis by genistein on HepG2 cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

"Nutritional and chemopreventive anti-cancer agents up-regulate expression of p27Kip1, a cyclin-dependent kinase inhibitor, in mouse JB6 epidermal and human MCF7, MDA-MB-321 and AU565 breast cancer cells".

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Oncogenic PI3K and its role in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Combination of 5-fluorouracil and genistein induces apoptosis synergistically in chemo-resistant cancer cells through the modulation of AMPK and COX-2 signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Gene mutations and altered gene expression in azoxymethane-induced colon carcinogenesis in rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Chemopreventive potential of epigallocatechin gallate and genistein: evidence from epidemiological and laboratory studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Soy isoflavones and cancer prevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Phosphatidylinositol 3-kinase mediates proliferative signals in intestinal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Cell cycle and death control: long live Forkheads

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

The phosphoinositide 3-kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

p53-dependent transcriptional regulation of the APC promoter in colon cancer cells treated with DNA alkylating agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Low-dose genistein induces cyclin-dependent kinase inhibitors and G(1) cell-cycle arrest in human prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

The therapeutic potential of flavonoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Characterization of the murine cyclin-dependent kinase inhibitor gene p27Kip1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

p53 functional loss in a colon cancer cell line with two missense mutations (218leu and 248trp) on separate alleles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Biochemical targets of the isoflavone genistein in tumor cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Soybean phytoestrogen intake and cancer risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Genistein, a specific inhibitor of tyrosine-specific protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Colon cancer and the p53 oncogene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

p53 mutations in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

A transcriptionally active DNA-binding site for human p53 protein complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

21 June 2018

Effects of soybean extract on morphology and survival of Caco-2, SW620, and HT-29 cells

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-219

21 January 2018

Effects of soy isoflavones on apoptosis induction and G2-M arrest in human hepatoma cells involvement of caspase-3 activation, Bcl-2 and Bcl-XL downregulation, and Cdc2 kinase activity

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-219

21 January 2018

Inhibition of proliferation and induction of apoptosis by genistein in colon cancer HT-29 cells

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-219

21 January 2018

Genistein inhibits insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells: a possible mechanism of the growth inhibitory effect of Genistein

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-219

21 January 2018

Amplification of signal transduction capacity and down-regulation by drugs.

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-219

21 January 2018

Synergistic effects of dexamethasone and genistein on the expression of Cdk inhibitor p21WAF1/CIP1 in human hepatocellular and colorectal carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3134425

25 November 2018

Genistein, a component of soy, inhibits the expression of the EGF and ErbB2/Neu receptors in the rat dorsolateral prostate

1 reference

https://pubmed.ncbi.nlm.nih.gov/21639915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding specificities and affinities of egf domains for ErbB receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21639915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53-independent apoptosis induced by genistein in lung cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21639915

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1471-2407-11-219

1 reference

Europe PubMed Central

17 October 2017

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1 reference

Europe PubMed Central

17 October 2017

1 reference

Europe PubMed Central

17 October 2017

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