p53-dependent transcriptional regulation of the APC promoter in colon cancer cells treated with DNA alkylating agents (Q38302465)

1 September 2017

p53-dependent transcriptional regulation of the APC promoter in colon cancer cells treated with DNA alkylating agents (English)

1 reference

1 September 2017

1 reference

Jaiswal AS

1

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PubMed ID

11279192

1 September 2017

Narayan S

series ordinal

2

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PubMed ID

11279192

1 September 2017

language of work or name

English

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publication date

14 March 2001

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Journal of Biological Chemistry

1 September 2017

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1 September 2017

276

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1 September 2017

21

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1 September 2017

18193-18199

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Genetic pathways in colorectal and other cancers

1 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Inactivation of both APC alleles in an early stage of colon adenomas in a patient with familial adenomatous polyposis (FAP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

APC mutations occur early during colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Biology of the adenomatous polyposis coli tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

The molecular basis of Turcot's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Somatic mutations of the APC gene in primary breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Decreased expression of the adenomatous polyposis coli (Apc) and mutated in colorectal cancer (Mcc) genes in mouse lung neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Nuclear and cytoplasmic localizations of the adenomatous polyposis coli protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

The APC tumour suppressor has a nuclear export function.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M101298200

Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Stabilization of beta-catenin by genetic defects in melanoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

beta-catenin is a target for the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Association of the APC tumor suppressor protein with catenins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Association of the APC gene product with beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Lessons from hereditary colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

DNA damage induces phosphorylation of the amino terminus of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Requirement of ATM in phosphorylation of the human p53 protein at serine 15 following DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

hMutSalpha- and hMutLalpha-dependent phosphorylation of p53 in response to DNA methylator damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Activation of adenomatous polyposis coli (APC) gene expression by the DNA-alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine requires p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Upstream stimulating factor-1 (USF1) and USF2 bind to and activate the promoter of the adenomatous polyposis coli (APC) tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Identification of p53 as a sequence-specific DNA-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Definition of a consensus binding site for p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Differential regulation of p53-dependent and -independent proliferating cell nuclear antigen gene transcription by 12 S E1A oncoprotein requires CBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Expression of the APC gene after transfection into a colonic cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Three distinct signalling responses by murine fibroblasts to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Phosphorylation studies on rat p53 using the baculovirus expression system. Manipulation of the phosphorylation state with okadaic acid and influence on DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Cooperative actions of HIV-1 Vpr and p53 modulate viral gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

p53 regulates insulin-like growth factor-I (IGF-I) receptor expression and IGF-I-induced tyrosine phosphorylation in an osteosarcoma cell line: interaction between p53 and Sp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

TFIIH: a key component in multiple DNA transactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

Apoptosis and APC in colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

p21 is a universal inhibitor of cyclin kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M101298200

21 January 2018

Identifiers

DOI

10.1074/JBC.M101298200

1 reference

1 September 2017

1 reference

PubMed ID

11279192