STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia (Q31028277)

13 October 2017

STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia (English)

1 reference

13 October 2017

7

Teresa A Zimmers

1 reference

13 October 2017

Noelia Kunzevitzky

3

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Andrea Bonetto

object named as

Andrea Bonetto

1

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Sawsan Khuri

object named as

Sawsan Khuri

5

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author name string

Tufan Aydogdu

2

1 reference

13 October 2017

Denis C Guttridge

4

1 reference

13 October 2017

Leonidas G Koniaris

6

1 reference

13 October 2017

language of work or name

English

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publication date

20 July 2011

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13 October 2017

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13 October 2017

6

1 reference

13 October 2017

e22538

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13 October 2017

7

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Creative Commons Attribution 4.0 International

13 October 2017

start time

20 July 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3140523/fullTextXML

inferred from PubMed Central ID database lookup

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Two tales concerning skeletal muscle

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Cancer cachexia signaling pathways continue to emerge yet much still points to the proteasome

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Paradoxical effects of short- and long-term interleukin-6 exposure on liver injury and repair.

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Conditional activation of akt in adult skeletal muscle induces rapid hypertrophy

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IKKbeta/NF-kappaB activation causes severe muscle wasting in mice

21 June 2018

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Cancer cachexia is regulated by selective targeting of skeletal muscle gene products

21 June 2018

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The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors

21 June 2018

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Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression

21 June 2018

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Fibrinogen: a novel predictor of responsiveness in metastatic melanoma patients treated with bio-chemotherapy: IMI (italian melanoma inter-group) trial

21 June 2018

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Cytokines in the pathogenesis of cancer cachexia

21 June 2018

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A genome-wide analysis of the acute-phase response and its regulation by Stat3beta

21 June 2018

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Signalling pathways that mediate skeletal muscle hypertrophy and atrophy

21 June 2018

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Cachexia in cancer patients

21 June 2018

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Altered expression of skeletal muscle myosin isoforms in cancer cachexia

21 June 2018

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21 June 2018

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21 June 2018

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Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

21 June 2018

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Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

21 June 2018

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Identification of ubiquitin ligases required for skeletal muscle atrophy

21 June 2018

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Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver

21 June 2018

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Impact of the fibrinolytic enzyme system on prognosis and survival associated with non-small cell lung carcinoma

21 June 2018

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An empirical approach to characterizing trunk muscle coactivation using simulation input modeling techniques

21 June 2018

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21 June 2018

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Inhibition of experimental cancer cachexia by anti-cytokine and anti-cytokine-receptor therapy.

21 June 2018

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Kinase domain of the muscle-specific receptor tyrosine kinase (MuSK) is sufficient for phosphorylation but not clustering of acetylcholine receptors: required role for the MuSK ectodomain?

21 June 2018

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Regulation of scavenger receptor expression in smooth muscle cells by protein kinase C: a role for oxidative stress

21 June 2018

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Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member

21 June 2018

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The relationship between weight loss and interleukin 6 in non-small-cell lung cancer

21 June 2018

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Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice

21 June 2018

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Interleukin-6 cDNA transfected Lewis lung carcinoma cells show unaltered net tumour growth rate but cause weight loss and shortened survival in syngeneic mice

21 June 2018

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Participation of the transcription factor C/EBP delta in the acute-phase regulation of the human gene for complement component C3

21 June 2018

1 reference

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Regulation of the acute phase response by cytokines

21 June 2018

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Suramin interferes with interleukin-6 receptor binding in vitro and inhibits colon-26-mediated experimental cancer cachexia in vivo

21 June 2018

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

21 June 2018

1 reference

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Cytokine receptor signalling

21 June 2018

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Symptoms potentially influencing weight loss in a cancer population. Correlations with primary site, nutritional status, and chemotherapy administration

21 June 2018

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Experimental cancer cachexia induced by transplantable colon 26 adenocarcinoma in mice

21 June 2018

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Chinese hamster ovarian cells transfected with the murine interleukin-6 gene cause hypercalcemia as well as cachexia, leukocytosis and thrombocytosis in tumor-bearing nude mice

21 June 2018

1 reference

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Evidence for the involvement of interleukin 6 in experimental cancer cachexia

21 June 2018

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Control of food intake in cancer cachexia: a challenge and a tool

21 June 2018

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Interleukin-6 is an important in vivo inhibitor of intestinal epithelial cell death in mice

21 June 2018

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Interleukin-6 inhibits oxidative injury and necrosis after extreme liver resection.

25 November 2018

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Muscle ring finger 1, but not muscle ring finger 2, regulates cardiac hypertrophy in vivo

25 November 2018

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RAPID PULMONARY EXPRESSION OF ACUTE-PHASE REACTANTS AFTER LOCAL LIPOPOLYSACCHARIDE EXPOSURE IN MICE IS FOLLOWED BY AN INTERLEUKIN-6 MEDIATED SYSTEMIC ACUTE-PHASE RESPONSE

25 November 2018

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Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice

25 November 2018

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Massive liver growth in mice induced by systemic interleukin 6 administration.

25 November 2018

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Ectopic bone formation following temporalis muscle transposition for facial paralysis.

25 November 2018

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Fibrinogen synthesis is elevated in fasting cancer patients with an acute phase response.

25 November 2018

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Characterization of mice bearing subclones of colon 26 adenocarcinoma disqualifies interleukin-6 as the sole inducer of cachexia.

25 November 2018

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Growth Differentiation Factor-15: Induction in Liver Injury Through p53 and Tumor Necrosis Factor-Independent Mechanisms1

25 November 2018

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12 December 2020

Manifestations of cancer cachexia induced by colon 26 adenocarcinoma are not fully ascribable to interleukin-6

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12 December 2020

Involvement of human interleukin 6 in experimental cachexia induced by a human uterine cervical carcinoma xenograft

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12 December 2020

Muscle undergoes atrophy in association with increase of lysosomal cathepsin activity in interleukin-6 transgenic mouse

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12 December 2020

Establishment and characterization of cachexia-inducing and -non-inducing clones of murine colon 26 carcinoma

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12 December 2020

Elevated circulating interleukin-6 is associated with an acute-phase response but reduced fixed hepatic protein synthesis in patients with cancer

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12 December 2020

Bcr in vascular smooth muscle cells involvement of Ras and Raf-1 activation by Bcr

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12 December 2020

Resolving the role of IL-6 in liver regeneration

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12 December 2020

A signaling role for dystrophin: inhibiting skeletal muscle atrophy pathways

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12 December 2020

Changes in nutritional, functional, and inflammatory markers in advanced pancreatic cancer

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12 December 2020

Brief muscle hypoperfusion/hyperemia: an ergogenic aid?

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12 December 2020

Acute-phase protein response and survival duration of patients with pancreatic cancer

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12 December 2020

10.1371/JOURNAL.PONE.0022538

Identifiers

DOI

1 reference

13 October 2017

0 references

1 reference

13 October 2017

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