Molecular mechanisms modulating muscle mass (Q35203025)

7 August 2017

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title

Molecular mechanisms modulating muscle mass (English)

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7 August 2017

David J Glass

1

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7 August 2017

publication date

1 August 2003

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Trends in Molecular Medicine

7 August 2017

published in

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7 August 2017

volume

9

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7 August 2017

issue

8

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7 August 2017

page(s)

344-350

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Protein turnover measured in vivo and in vitro in muscles undergoing compensatory growth and subsequent denervation atrophy

7 August 2017

cites work

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7 January 2021

Insulin and IGF-I induce pronounced hypertrophy of skeletal myofibers in tissue culture

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7 January 2021

Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice

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7 January 2021

Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle

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7 January 2021

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.

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7 January 2021

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

What do we really know about the ubiquitin-proteasome pathway in muscle atrophy?

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Induction of cachexia in mice by systemically administered myostatin.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Mechanisms of muscle wasting. The role of the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Identification of ubiquitin ligases required for skeletal muscle atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Cellular actions of the insulin-like growth factor binding proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Targeted expression of IGF-1 transgene to skeletal muscle accelerates muscle and motor neuron regeneration.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Regulation of Raf-Akt Cross-talk

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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Phosphorylation and regulation of Raf by Akt (protein kinase B)

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Ras is involved in nerve-activity-dependent regulation of muscle genes.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Role of translocation in the activation and function of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Akt/protein kinase B promotes organ growth in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Myogenic Akt signaling regulates blood vessel recruitment during myofiber growth.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Specific beta1 integrin site selectively regulates Akt/protein kinase B signaling via local activation of protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Protein phosphatase 2A: the Trojan Horse of cellular signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Identification of a novel protein phosphatase 2A regulatory subunit highly expressed in muscle

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways

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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Protean PTEN: form and function

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

The lipid phosphatase SHIP2 controls insulin sensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Regulation of cellular growth by the Drosophila target of rapamycin dTOR

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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Drosophila S6 kinase: a regulator of cell size

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load

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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

A protein kinase B-dependent and rapamycin-sensitive pathway controls skeletal muscle growth but not fiber type specification

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Phosphorylation and activation of p70s6k by PDK1

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Activation of S6K1 (p70 ribosomal protein S6 kinase 1) requires an initial calcium-dependent priming event involving formation of a high-molecular-mass signalling complex.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Regulation of eIF-4E BP1 phosphorylation by mTOR.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Two motifs in the translational repressor PHAS-I required for efficient phosphorylation by mammalian target of rapamycin and for recognition by raptor

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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function

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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycinassociated protein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Glycogen synthase kinase-3beta: a novel regulator of cardiac hypertrophy and development.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Patterns of gene expression in atrophying skeletal muscles: response to food deprivation.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Atrophy responses to muscle inactivity. II. Molecular markers of protein deficits

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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Inhibitors of the proteasome reduce the accelerated proteolysis in atrophying rat skeletal muscles

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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Ubiquitin conjugation by the N-end rule pathway and mRNAs for its components increase in muscles of diabetic rats

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Sepsis upregulates the gene expression of multiple ubiquitin ligases in skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

The RING finger domain: a recent example of a sequence-structure family

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Does this have a familiar RING?

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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

The tripartite motif family identifies cell compartments

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Transient association of titin and myosin with microtubules in nascent myofibrils directed by the MURF2 RING-finger protein

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

The SCF ubiquitin ligase: an extended look

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Double muscling in cattle due to mutations in the myostatin gene

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Inhibition of myostatin in adult mice increases skeletal muscle mass and strength

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Functional improvement of dystrophic muscle by myostatin blockade.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

Signalling pathways that mediate skeletal muscle hypertrophy and atrophy

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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900138-2

7 January 2021

10.1016/S1471-4914(03)00138-2

Identifiers

DOI

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7 August 2017

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