A method for analysis and design of metabolism using metabolomics data and kinetic models: Application on lipidomics using a novel kinetic model of sphingolipid metabolism. (Q31084839)

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English	A method for analysis and design of metabolism using metabolomics data and kinetic models: Application on lipidomics using a novel kinetic model of sphingolipid metabolism.	scientific article

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3 April 2020

A method for analysis and design of metabolism using metabolomics data and kinetic models: Application on lipidomics using a novel kinetic model of sphingolipid metabolism (English)

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Vassily Hatzimanikatis

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Georgios Savoglidis

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3 April 2020

Aline Xavier da Silveira Dos Santos

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Isabelle Riezman

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Paolo Angelino

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Howard Riezman

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23 April 2016

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Metabolic Engineering

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46-62

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3 April 2020

Metabolic control design.

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7 January 2021

Kinetic models in industrial biotechnology - Improving cell factory performance

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Simulation and validation of modelled sphingolipid metabolism in Saccharomyces cerevisiae

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Coordination of the dynamics of yeast sphingolipid metabolism during the diauxic shift.

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Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast

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Inverse metabolic engineering: A strategy for directed genetic engineering of useful phenotypes.

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Functions of lipid rafts in biological membranes

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Towards kinetic modeling of genome-scale metabolic networks without sacrificing stoichiometric, thermodynamic and physiological constraints.

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Comparative lipidomic analysis of mouse and human brain with Alzheimer disease.

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Establishing a platform cell factory through engineering of yeast acetyl-CoA metabolism

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Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis

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Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks

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Sphingolipid functions in Saccharomyces cerevisiae

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Lipid droplets finally get a little R-E-S-P-E-C-T.

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Metabolic control and its analysis. Additional relationships between elasticities and control coefficients.

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Tradeoff between enzyme and metabolite efficiency maintains metabolic homeostasis upon perturbations in enzyme capacity.

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Mutant analysis reveals complex regulation of sphingolipid long chain base phosphates and long chain bases during heat stress in yeast

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Lcb4p is a key regulator of ceramide synthesis from exogenous long chain sphingoid base in Saccharomyces cerevisiae

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Inferring genetic networks and identifying compound mode of action via expression profiling

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Functional interactions between sphingolipids and sterols in biological membranes regulating cell physiology

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Integration of lipidomics and transcriptomics data towards a systems biology model of sphingolipid metabolism

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Hydroxylation of Saccharomyces cerevisiae ceramides requires Sur2p and Scs7p

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Nonlinear metabolic control analysis.

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MCA has more to say.

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Effects of spatiotemporal variations on metabolic control: approximate analysis using (log)linear kinetic models

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Proteomics: theoretical and experimental considerations.

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Principles of transcriptional control in the metabolic network of Saccharomyces cerevisiae

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Involvement of yeast sphingolipids in the heat stress response of Saccharomyces cerevisiae

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Ceramide/long-chain base phosphate rheostat in Saccharomyces cerevisiae: regulation of ceramide synthesis by Elo3p and Cka2p

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Sphingolipid metabolism diseases

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Microbial acetyl-CoA metabolism and metabolic engineering

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Lipid rafts as a membrane-organizing principle

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Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response.

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Identification and characterization of Saccharomyces cerevisiae dihydrosphingosine-1-phosphate phosphatase

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The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis

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3 April 2020

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