A two stage click-based library of protein tyrosine phosphatase inhibitors (Q33260614)

24 July 2017

title

A two stage click-based library of protein tyrosine phosphatase inhibitors (English)

1 reference

24 July 2017

Jian Xie

1

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24 July 2017

Christopher T Seto

series ordinal

2

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24 July 2017

language of work or name

English

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publication date

12 October 2006

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Bioorganic & Medicinal Chemistry

24 July 2017

published in

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24 July 2017

volume

15

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24 July 2017

issue

1

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24 July 2017

page(s)

458-473

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Rapid assembly and in situ screening of bidentate inhibitors of protein tyrosine phosphatases

24 July 2017

cites work

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Parallel synthesis of a library of bidentate protein tyrosine phosphatase inhibitors based on the alpha-ketoacid motif

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Fragment screening and assembly: a highly efficient approach to a selective and cell active protein tyrosine phosphatase 1B inhibitor

21 June 2018

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21 June 2018

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21 June 2018

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Peptidic α-Ketocarboxylic Acids and Sulfonamides as Inhibitors of Protein Tyrosine Phosphatases

21 June 2018

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Discovery of a potent, selective protein tyrosine phosphatase 1B inhibitor using a linked-fragment strategy

21 June 2018

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Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP

21 June 2018

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Crystal structure of PTP1B complexed with a potent and selective bidentate inhibitor

21 June 2018

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21 June 2018

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A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

21 June 2018

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Divalent and trivalent alpha-ketocarboxylic acids as inhibitors of protein tyrosine phosphatases

21 June 2018

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The structure of PTP-1B in complex with a peptide inhibitor reveals an alternative binding mode for bisphosphonates

21 June 2018

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The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3

21 June 2018

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21 June 2018

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21 June 2018

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Click Chemistry: Diverse Chemical Function from a Few Good Reactions

21 June 2018

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Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

21 June 2018

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2-(oxalylamino)-benzoic acid is a general, competitive inhibitor of protein-tyrosine phosphatases

21 June 2018

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Positive and negative regulation of Src-family membrane kinases by CD45.

21 June 2018

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Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

21 June 2018

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21 June 2018

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Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design

21 June 2018

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Impaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient mice

21 June 2018

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The Cys(X)5Arg catalytic motif in phosphoester hydrolysis

21 June 2018

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Characterization of the major protein-tyrosine-phosphatases of human placenta.

21 June 2018

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Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines

21 June 2018

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Cell surface labeling of Escherichia coli via copper(I)-catalyzed [3+2] cycloaddition

21 June 2018

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Model systems for flavoenzyme activity: site-isolated redox behavior in flavin-functionalized random polystyrene copolymers.

31 October 2018

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In situ click chemistry: enzyme inhibitors made to their own specifications

31 October 2018

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Presentation and detection of azide functionality in bacterial cell surface proteins

31 October 2018

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Covalent display of oligosaccharide arrays in microtiter plates

31 October 2018

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Spin control in ladderlike hexanuclear copper(II) complexes with metallacyclophane cores

31 October 2018

1 reference

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Activity-based protein profiling in vivo using a copper(i)-catalyzed azide-alkyne [3 + 2] cycloaddition

31 October 2018

1 reference

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Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition

31 October 2018

1 reference

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Probing the molecular basis for potent and selective protein-tyrosine phosphatase 1B inhibition

31 October 2018

1 reference

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Design, synthesis, and evaluation of matrix metalloprotease inhibitors bearing cyclopropane-derived peptidomimetics as P1' and P2' replacements

31 October 2018

1 reference

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The difluoromethylenesulfonic acid group as a monoanionic phosphate surrogate for obtaining PTP1B inhibitors

31 October 2018

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Novel synthesis of 4,5-diarylphenanthrenes via C2-C6 cyclization of benzannulated enyne-allenes

31 October 2018

1 reference

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Efficiency and Fidelity in a Click-Chemistry Route to Triazole Dendrimers by the Copper(I)-Catalyzed Ligation of Azides and Alkynes

31 October 2018

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Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks

31 October 2018

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12 December 2020

Rational design of an enneanuclear copper(II) complex with a metallacyclophane core

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12 December 2020

Synthesis of Bestatin, a Potent Inhibitor of Leukotriene A4 Hydrolase, by an N3 Nucleophile Reaction to a Non-protected Diol

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12 December 2020

Potent Inhibition of Insulin Receptor Dephosphorylation by a Hexamer Peptide Containing the Phosphotyrosyl Mimetic F2Pmp

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Synthesis and biological evaluation of NK1 antagonists derived from L-tryptophan

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12 December 2020

Protein-tyrosine phosphatase inhibition by a peptide containing the phosphotyrosyl mimetic, L-O-malonyltyrosine

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Progestin 16 alpha, 17 alpha-dioxolane ketals as molecular probes for the progesterone receptor: synthesis, binding affinity, and photochemical evaluation

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Novel phosphate mimetics for the design of non-peptidyl inhibitors of protein tyrosine phosphatases

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12 December 2020

10.1016/J.BMC.2006.09.036

Identifiers

DOI

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24 July 2017

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24 July 2017

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