Development and application of hybrid structure based method for efficient screening of ligands binding to G-protein coupled receptors (Q33260986)

24 July 2017

Development and application of hybrid structure based method for efficient screening of ligands binding to G-protein coupled receptors (English)

1 reference

G protein-coupled receptor

24 July 2017

0 references

protein structure

0 references

author name string

Sandhya Kortagere

series ordinal

1

1 reference

PubMed ID

17054015

24 July 2017

William J Welsh

series ordinal

2

1 reference

24 July 2017

13 October 2006

1 reference

Journal of Computer - Aided Molecular Design

24 July 2017

1 reference

24 July 2017

20

1 reference

24 July 2017

12

1 reference

24 July 2017

789-802

1 reference

https://scigraph.springernature.com/pub.10.1007/s10822-006-9077-8

24 July 2017

0 references

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Ab initio computational modeling of loops in G-protein-coupled receptors: lessons from the crystal structure of rhodopsin

21 June 2018

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Development and virtual screening of target libraries

21 June 2018

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Long dynamics simulations of proteins using atomistic force fields and a continuum representation of solvent effects: calculation of structural and dynamic properties

21 June 2018

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Multiple signaling states of G-protein-coupled receptors

21 June 2018

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Changes in interhelical hydrogen bonding upon rhodopsin activation

21 June 2018

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Virtual screening of chemical libraries

21 June 2018

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Certain 1,4-disubstituted aromatic piperidines and piperazines with extreme selectivity for the dopamine D4 receptor interact with a common receptor microdomain

21 June 2018

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The many roles of computation in drug discovery

21 June 2018

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5-HT1-like receptor agonists and the pathophysiology of migraine

21 June 2018

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21 June 2018

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21 June 2018

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Identification of G protein-coupled receptor genes from the human genome sequence

21 June 2018

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Clinical and molecular genetics of ADHD and Tourette syndrome. Two related polygenic disorders

21 June 2018

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Statistical potentials and scoring functions applied to protein-ligand binding

21 June 2018

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beta(2)-adrenoceptor agonists inhibit release of eosinophil-activating cytokines from human airway smooth muscle cells

21 June 2018

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Hinges, swivels and switches: the role of prolines in signalling via transmembrane alpha-helices

21 June 2018

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Agonist-induced conformational changes at the cytoplasmic side of transmembrane segment 6 in the beta 2 adrenergic receptor mapped by site-selective fluorescent labeling.

21 June 2018

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Crystal structure of rhodopsin: A G protein-coupled receptor

21 June 2018

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Atypical antipsychotic agents: a critical review

21 June 2018

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21 June 2018

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Mutation of a highly conserved aspartic acid in the beta2 adrenergic receptor: constitutive activation, structural instability, and conformational rearrangement of transmembrane segment 6.

21 June 2018

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Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity

21 June 2018

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The many faces of G protein signaling

21 June 2018

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Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes.

21 June 2018

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Agonists induce conformational changes in transmembrane domains III and VI of the beta2 adrenoceptor

21 June 2018

1 reference

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Development and validation of a genetic algorithm for flexible docking

21 June 2018

1 reference

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Evaluation of comparative protein modeling by MODELLER

21 June 2018

1 reference

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Preclinical characterization of the potential of the putative atypical antipsychotic MDL 100,907 as a potent 5-HT2A antagonist with a favorable CNS safety profile

21 June 2018

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

21 June 2018

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MOPAC: a semiempirical molecular orbital program

21 June 2018

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Characterization of the binding domain of the beta-adrenergic receptor with the fluorescent antagonist carazolol. Evidence for a buried ligand binding site

21 June 2018

1 reference

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G proteins and the mechanism of action of hormones, neurotransmitters, and autocrine and paracrine regulatory factors

21 June 2018

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The GTPase superfamily: conserved structure and molecular mechanism

21 June 2018

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Dyskinesias Associated with Tricyclic Antidepressants

21 June 2018

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A schizophreniform behavioral psychosis mediated by dopamine

21 June 2018

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Neuroleptic drug interactions with norepinephrine alpha receptor binding sites in rat brain

21 June 2018

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Mechanism of action of β-blockers in hypertension

21 June 2018

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The role of Glu181 in the photoactivation of rhodopsin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756463

Reciprocal mutations in TM2/TM3 in a D2 dopamine receptor background confirms the importance of this microdomain as a selective determinant of para-halogenated 1,4-disubstituted aromatic piperazines

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756463

The contribution of C alpha-H...O hydrogen bonds to membrane protein stability depends on the position of the amide

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756463

Implicit solvent simulations of peptide interactions with anionic lipid membranes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756463

Shape signatures: a new approach to computer-aided ligand- and receptor-based drug design

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756463

Protein-based virtual screening of chemical databases. II. Are homology models of G-Protein Coupled Receptors suitable targets?

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756463

Prokink: a protocol for numerical evaluation of helix distortions by proline.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756463

A general and fast scoring function for protein-ligand interactions: a simplified potential approach.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756463

The SWISS-PROT protein sequence database: its relevance to human molecular medical research.

31 October 2018

1 reference

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SMART: a solvent-accessible triangulated surface generator for molecular graphics and boundary element applications.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2756463

Long-Term Antidepressant Treatment Decreases Spiroperidol-Labeled Serotonin Receptor Binding

31 October 2018

1 reference

12 December 2020

A compendium of specific motifs for diagnosing GPCR subtypes

1 reference

12 December 2020

Three-dimensional representations of G protein-coupled receptor structures and mechanisms

1 reference

12 December 2020

Deficit and nondeficit forms of schizophrenia: the concept

1 reference

12 December 2020

Rhodopsin activation follows precoupling with transducin: inferences from computational analysis

1 reference

12 December 2020

Mapping the binding-site crevice of the D2 receptor

1 reference

12 December 2020

10.1007/S10822-006-9077-8

Identifiers

DOI

1 reference

journals/jcamd/KortagereW06

24 July 2017

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

24 July 2017

1 reference

PubMed ID

17054015