p21 is decreased in polycystic kidney disease and leads to increased epithelial cell cycle progression: roscovitine augments p21 levels (Q33294928)

25 July 2017

p21 is decreased in polycystic kidney disease and leads to increased epithelial cell cycle progression: roscovitine augments p21 levels (English)

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polycystic kidney disease

25 July 2017

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Jin-Young Park

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25 July 2017

William E Schutzer

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25 July 2017

Jessie N Lindsley

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25 July 2017

Susan P Bagby

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25 July 2017

Terry T Oyama

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25 July 2017

Sharon Anderson

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25 July 2017

Robert H Weiss

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25 July 2017

22 August 2007

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25 July 2017

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25 July 2017

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25 July 2017

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describes a project that uses

25 July 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2045080/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1186/1471-2369-8-12

0 references

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21 June 2018

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Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: ETS-1 regulates basal and and inducible p21WAF1/Cip: ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting [...]

21 June 2018

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PKD1 induces p21(waf1) and regulation of the cell cycle via direct activation of the JAK-STAT signaling pathway in a process requiring PKD2

21 June 2018

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Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

21 June 2018

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Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells

21 June 2018

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p21(Waf1/Cip1) is an assembly factor required for platelet-derived growth factor-induced vascular smooth muscle cell proliferation

21 June 2018

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21 June 2018

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21 June 2018

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New functional activities for the p21 family of CDK inhibitors

21 June 2018

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p21 is a universal inhibitor of cyclin kinases

21 June 2018

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 June 2018

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21 June 2018

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21 June 2018

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Factors affecting the progression of renal disease in autosomal-dominant polycystic kidney disease

21 June 2018

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Cytosolic p21Waf1/Cip1 increases cell cycle transit in vascular smooth muscle cells

21 June 2018

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Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine.

21 January 2018

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Missense mutation in sterile alpha motif of novel protein SamCystin is associated with polycystic kidney disease in (cy/+) rat.

21 January 2018

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21 January 2018

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Gender and the effect of gonadal hormones on the progression of inherited polycystic kidney disease in rats.

21 January 2018

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Exogenous attenuation of p21(Waf1/Cip1) decreases mesangial cell hypertrophy as a result of hyperglycemia and IGF-1.

21 January 2018

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Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation

21 January 2018

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High-dose estrogen and clinical selective estrogen receptor modulators induce growth arrest, p21, and p53 in primate ovarian surface epithelial cells

21 January 2018

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Modulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by cell cycle inhibitors

21 January 2018

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Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease

21 January 2018

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Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD).

21 January 2018

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Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma

21 January 2018

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p21 is a prognostic marker for renal cell carcinoma: implications for novel therapeutic approaches.

21 January 2018

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The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation.

21 January 2018

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Inhibition of mTOR signaling with rapamycin attenuates renal hypertrophy in the early diabetic mice

21 January 2018

1 reference

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Induction of p21WAF1 expression protects HT29 colon cancer cells from apoptosis induced by cryoinjury.

21 January 2018

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31 October 2018

Identifiers

DOI

10.1186/1471-2369-8-12

1 reference

Dimensions Publication ID

25 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2369-8-12

9 September 2019

1 reference

25 July 2017

1 reference