Inhibition of anthrax lethal toxin-induced cytolysis of RAW264.7 cells by celastrol (Q33313876)

25 July 2017

Inhibition of anthrax lethal toxin-induced cytolysis of RAW264.7 cells by celastrol (English)

1 reference

25 July 2017

Sarah Chapelsky

1

1 reference

25 July 2017

Sarah Batty

series ordinal

2

1 reference

25 July 2017

Mia Frost

series ordinal

3

1 reference

25 July 2017

Jeremy Mogridge

series ordinal

4

1 reference

25 July 2017

language of work or name

English

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publication date

9 January 2008

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25 July 2017

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25 July 2017

3

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25 July 2017

1

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25 July 2017

e1421

1 reference

Creative Commons Attribution 4.0 International

25 July 2017

start time

9 January 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Proteasomes control caspase-1 activation in anthrax lethal toxin-mediated cell killing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Mitochondrial proteins Bnip3 and Bnip3L are involved in anthrax lethal toxin-induced macrophage cell death.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Drug discovery in the ubiquitin-proteasome system.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent proteasome inhibitor and suppresses human prostate cancer growth in nude mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

New insights into the functions of anthrax toxin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

The ubiquitin-proteasome system

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Roles of macrophages and neutrophils in the early host response to Bacillus anthracis spores in a mouse model of infection

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Mitochondrial impairment is a critical event in anthrax lethal toxin-induced cytolysis of murine macrophages

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Anthrax lethal toxin-mediated killing of human and murine dendritic cells impairs the adaptive immune response

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

BRAF status and mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 activity indicate sensitivity of melanoma cells to anthrax lethal toxin

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Anthrax toxin receptor 2 mediates Bacillus anthracis killing of macrophages following spore challenge

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Differentiation of human monocytic cell lines confers susceptibility to Bacillus anthracis lethal toxin.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Celastrols as inducers of the heat shock response and cytoprotection.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Toxin-induced resistance in Bacillus anthracis lethal toxin-treated macrophages.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

NALPs: a novel protein family involved in inflammation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Anthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent process

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNgamma-induced release of NO and TNFalpha

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Proteasome activity is required for anthrax lethal toxin to kill macrophages

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Germination of Bacillus anthracis spores within alveolar macrophages

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Anthrax protective antigen forms oligomers during intoxication of mammalian cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2170518

Anthrax lethal toxin blocks MAPK kinase-dependent IL-2 production in CD4+ T cells

14 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001421

Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001421

Inhibition of mitogen-activated protein kinase signalling by Bacillus anthracis lethal toxin causes destabilization of interleukin-8 mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001421

High bactericidal efficiency of type iia phospholipase A2 against Bacillus anthracis and inhibition of its secretion by the lethal toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001421

Anthrax lethal toxin has direct and potent inhibitory effects on B cell proliferation and immunoglobulin production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001421

Anthrax lethal toxin paralyzes neutrophil actin-based motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001421

Celastrol protects against MPTP- and 3-nitropropionic acid-induced neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001421

Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001421

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0001421

Bacillus anthracis Toxins Inhibit Human Neutrophil NADPH Oxidase Activity

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18183301

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18183301

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0001421

1 reference

25 July 2017

0 references

1 reference

25 July 2017

1 reference