A randomized, placebo-controlled phase 2 study of ganitumab (AMG 479) or conatumumab (AMG 655) in combination with gemcitabine in patients with metastatic pancreatic cancer (Q33401816)

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English	A randomized, placebo-controlled phase 2 study of ganitumab (AMG 479) or conatumumab (AMG 655) in combination with gemcitabine in patients with metastatic pancreatic cancer	scientific article

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scholarly article

1 reference

Europe PubMed Central

26 July 2017

A randomized, placebo-controlled phase 2 study of ganitumab (AMG 479) or conatumumab (AMG 655) in combination with gemcitabine in patients with metastatic pancreatic cancer (English)

1 reference

Europe PubMed Central

26 July 2017

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pancreatic cancer

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based on heuristic

inferred from title

author name string

H L Kindler

1

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Europe PubMed Central

26 July 2017

D A Richards

2

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Europe PubMed Central

26 July 2017

L E Garbo

3

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Europe PubMed Central

26 July 2017

E B Garon

4

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Europe PubMed Central

26 July 2017

J J Stephenson

5

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Europe PubMed Central

26 July 2017

C M Rocha-Lima

6

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Europe PubMed Central

26 July 2017

H Safran

7

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Europe PubMed Central

26 July 2017

D Chan

8

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Europe PubMed Central

26 July 2017

D M Kocs

9

1 reference

Europe PubMed Central

26 July 2017

F Galimi

10

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Europe PubMed Central

26 July 2017

J McGreivy

11

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Europe PubMed Central

26 July 2017

S L Bray

12

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Europe PubMed Central

26 July 2017

Y Hei

13

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Europe PubMed Central

26 July 2017

E G Feigal

14

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Europe PubMed Central

26 July 2017

E Loh

15

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Europe PubMed Central

26 July 2017

C S Fuchs

16

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Europe PubMed Central

26 July 2017

publication date

13 June 2012

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26 July 2017

Annals of Oncology

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26 July 2017

23

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Europe PubMed Central

26 July 2017

11

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Europe PubMed Central

26 July 2017

2834-2842

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Europe PubMed Central

26 July 2017

Cancer statistics, 2010

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Phase III randomized comparison of gemcitabine versus gemcitabine plus capecitabine in patients with advanced pancreatic cancer

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Phase III, randomized study of gemcitabine and oxaliplatin versus gemcitabine (fixed-dose rate infusion) compared with gemcitabine (30-minute infusion) in patients with pancreatic carcinoma E6201: a trial of the Eastern Cooperative Oncology Group

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Randomized phase III trial of gemcitabine plus cisplatin compared with single-agent gemcitabine as first-line treatment of patients with advanced pancreatic cancer: the GIP-1 study

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: phase III trial of the Cancer and Leukemia Group B (CALGB 80303).

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Coexpression of IGF-1R and c-Src proteins in human pancreatic ductal adenocarcinoma

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Emerging pathways and future targets for the molecular therapy of pancreatic cancer

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

AMG 479, a fully human anti-insulin-like growth factor receptor type I monoclonal antibody, inhibits the growth and survival of pancreatic carcinoma cells

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Igf1r as a therapeutic target in a mouse model of basal-like breast cancer

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Safety and pharmacokinetics of ganitumab (AMG 479) combined with sorafenib, panitumumab, erlotinib, or gemcitabine in patients with advanced solid tumors.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Effects and expression of TRAIL and its apoptosis-promoting receptors in human pancreatic cancer.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Phase I, pharmacokinetic, and pharmacodynamic study of AMG 479, a fully human monoclonal antibody to insulin-like growth factor receptor 1.

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Front-line treatment of inoperable or metastatic pancreatic cancer with gemcitabine and capecitabine: an intergroup, multicenter, phase II study

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Capecitabine plus oxaliplatin (CapOx) versus capecitabine plus gemcitabine (CapGem) versus gemcitabine plus oxaliplatin (mGemOx): final results of a multicenter randomized phase II trial in advanced pancreatic cancer

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Phase II trial of gemcitabine (2,2'-difluorodeoxycytidine) in patients with adenocarcinoma of the pancreas

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Recent developments in palliative chemotherapy for locally advanced and metastatic pancreas cancer

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Randomized phase II trials: a long-term investment with promising returns

1 reference

https://api.crossref.org/works/10.1093%2FANNONC%2FMDS142

21 January 2018

Identifiers

10.1093/ANNONC/MDS142

1 reference

Europe PubMed Central

26 July 2017

1 reference

Europe PubMed Central

26 July 2017

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