Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells (Q33413336)

26 July 2017

Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells (English)

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Human Induced Pluripotent Stem Cells

26 July 2017

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15

Shinya Yamanaka

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26 July 2017

18

Koji Eto

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26 July 2017

3

Shinji Hirata

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26 July 2017

6

Kiyosumi Ochi

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12

Keisuke Okita

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26 July 2017

Sou Nakamura

1

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26 July 2017

Naoya Takayama

2

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26 July 2017

Hideya Seo

4

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26 July 2017

Hiroshi Endo

5

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26 July 2017

Ken-ichi Fujita

7

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26 July 2017

Tomo Koike

8

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26 July 2017

Ken-ichi Harimoto

9

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26 July 2017

Takeaki Dohda

10

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Akira Watanabe

11

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Nobuyasu Takahashi

13

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Akira Sawaguchi

14

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26 July 2017

Hiromitsu Nakauchi

16

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26 July 2017

Satoshi Nishimura

17

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26 July 2017

language of work or name

English

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publication date

13 February 2014

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26 July 2017

14

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4

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26 July 2017

535-548

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Induction of pluripotent stem cells from adult human fibroblasts by defined factors

26 July 2017

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24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/J.CELL.2007.11.019

Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Generation and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndrome

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Infusion of mature megakaryocytes into mice yields functional platelets

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Challenges and promises for the development of donor-independent platelet transfusions

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Immortalization of erythroblasts by c-MYC and BCL-XL enables large-scale erythrocyte production from human pluripotent stem cells

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Gene expression analysis during platelet-like particle production in phorbol myristate acetate-treated MEG-01 cells

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Congenital amegakaryocytic thrombocytopenia iPS cells exhibit defective MPL-mediated signaling

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Establishment of a human leukaemic cell line (CMK) with megakaryocytic characteristics from a Down's syndrome patient with acute megakaryoblastic leukaemia

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Diagnosis and management of refractoriness to platelet transfusion

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11 October 2022

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Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice

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11 October 2022

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Transcriptional control of the core cell-death machinery

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Dynamic Visualization of Thrombopoiesis Within Bone Marrow

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Platelet receptor shedding

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

c-Myc functionally cooperates with Bax to induce apoptosis

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Efficient establishment of human embryonic stem cell lines and long-term maintenance with stable karyotype by enzymatic bulk passage

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

A novel flow cytometry-based platelet aggregation assay.

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

A systems-biology analysis of isogenic megakaryocytic and granulocytic cultures identifies new molecular components of megakaryocytic apoptosis

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

BclxL overexpression in megakaryocytes leads to impaired platelet fragmentation

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Clonal analysis unveils self-renewing lineage-restricted progenitors generated directly from hematopoietic stem cells

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Caspases and mitochondria in c-Myc-induced apoptosis: identification of ATM as a new target of caspases

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

The biogenesis of platelets from megakaryocyte proplatelets

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Characterization of stage progression in chronic myeloid leukemia by DNA microarray with purified hematopoietic stem cells

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Role of platelet surface glycoprotein Ibalpha and P-selectin in the clearance of transfused platelet concentrates

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Increased megakaryopoiesis in cultures of CD34-enriched cord blood cells maintained at 39 degrees C.

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Two differential flows in a bioreactor promoted platelet generation from human pluripotent stem cell-derived megakaryocytes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Lnk regulates integrin alphaIIbbeta3 outside-in signaling in mouse platelets, leading to stabilization of thrombus development in vivo

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.STEM.2014.01.011

Identifiers

DOI

10.1016/J.STEM.2014.01.011

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26 July 2017

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