Targeting cell surface TLR7 for therapeutic intervention in autoimmune diseases (Q33420162)

26 July 2017

Targeting cell surface TLR7 for therapeutic intervention in autoimmune diseases (English)

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26 July 2017

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Atsuo Kanno

1

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26 July 2017

Natsuko Tanimura

2

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26 July 2017

Masayuki Ishizaki

3

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Kentaro Ohko

4

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Yuji Motoi

5

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Masahiro Onji

6

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Ryutaro Fukui

7

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Takaichi Shimozato

8

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Kazuhide Yamamoto

9

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Takuma Shibata

10

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Shigetoshi Sano

11

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Akiko Sugahara-Tobinai

12

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Toshiyuki Takai

13

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Umeharu Ohto

14

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Toshiyuki Shimizu

15

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Shin-ichiroh Saitoh

16

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Kensuke Miyake

17

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language of work or name

English

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publication date

4 February 2015

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26 July 2017

Nature Communications

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26 July 2017

6

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26 July 2017

6119

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https://scigraph.springernature.com/pub.10.1038/ncomms7119

26 July 2017

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cites work

Toll-like receptor function and signaling

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https://api.crossref.org/works/10.1038%2FNCOMMS7119

Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Intracellular toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Transmembrane mutations in Toll-like receptor 9 bypass the requirement for ectodomain proteolysis and induce fatal inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

A Toll-like receptor 7, 8, and 9 antagonist inhibits Th1 and Th17 responses and inflammasome activation in a model of IL-23-induced psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

A novel antagonist of Toll-like receptors 7, 8 and 9 suppresses lupus disease-associated parameters in NZBW/F1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Essential role for Toll-like receptor 7 (TLR7)-unique cysteines in an intramolecular disulfide bond, proteolytic cleavage and RNA sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Splenectomy prolongs the effects of corticosteroids in mouse models of autoimmune hepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Primary blood neutrophils express a functional cell surface Toll-like receptor 9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

UNC93B1 is essential for the plasma membrane localization and signaling of Toll-like receptor 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

The tetraspanin CD63 is required for efficient IgE-mediated mast cell degranulation and anaphylaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Anti-CD63 antibodies suppress IgE-dependent allergic reactions in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

inferred from DOI database lookup

7 January 2021

based on heuristic

Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7119

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS7119

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Dimensions Publication ID

26 July 2017

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