SB203580 Modulates p38 MAPK Signaling and Dengue Virus-Induced Liver Injury by Reducing MAPKAPK2, HSP27, and ATF2 Phosphorylation (Q33430173)

26 July 2017

SB203580 Modulates p38 MAPK Signaling and Dengue Virus-Induced Liver Injury by Reducing MAPKAPK2, HSP27, and ATF2 Phosphorylation (English)

1 reference

Gopinathan Pillai Sreekanth

26 July 2017

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26901653%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Sansanee Noisakran

5

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31 May 2020

author name string

Aporn Chuncharunee

2

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31 May 2020

Aunchalee Sirimontaporn

3

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31 May 2020

Jutatip Panaampon

4

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31 May 2020

Pa-Thai Yenchitsomanus

6

1 reference

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31 May 2020

Thawornchai Limjindaporn

7

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31 May 2020

language of work or name

English

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publication date

22 February 2016

1 reference

26 July 2017

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31 May 2020

volume

11

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31 May 2020

issue

2

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31 May 2020

page(s)

e0149486

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Creative Commons Attribution 4.0 International

31 May 2020

copyright license

start time

22 February 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4764010/fullTextXML

inferred from PubMed Central ID database lookup

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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FasL/Fas pathway is involved in dengue virus induced apoptosis of the vascular endothelial cells

14 July 2018

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Dengue-2 infection and the induction of apoptosis in human primary monocytes

14 July 2018

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JNK phosphorylation, induced during dengue virus infection, is important for viral infection and requires the presence of cholesterol

14 July 2018

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Hepatic damage associated with dengue-2 virus replication in liver cells of BALB/c mice

14 July 2018

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Early clinical and biological features of severe clinical manifestations of dengue in Vietnamese adults

14 July 2018

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A clinical isolate of dengue virus and its proteins induce apoptosis in HMEC-1 cells: a possible implication in pathogenesis.

14 July 2018

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Gene expression profiling by microarray analysis reveals an important role for caspase-1 in dengue virus-induced p53-mediated apoptosis

14 July 2018

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Liver function test results and outcomes in children with acute liver failure due to dengue infection.

14 July 2018

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Induction of proinflammatory cytokines in primary human macrophages by influenza A virus (H5N1) is selectively regulated by IFN regulatory factor 3 and p38 MAPK.

14 July 2018

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Liver injury caused by antibodies against dengue virus nonstructural protein 1 in a murine model

14 July 2018

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Induction of p53-dependent and mitochondria-mediated cell death pathway by dengue virus infection of human and animal cells

14 July 2018

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Haematological and biochemical indicators for the early diagnosis of dengue viral infection

14 July 2018

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Sensitization to Fas-mediated apoptosis by dengue virus capsid protein.

14 July 2018

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Apoptosis in tissues from fatal dengue shock syndrome

14 July 2018

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CD40-CD40 Ligand Interactions Promote Trafficking of CD8+ T Cells into the Brain and Protection against West Nile Virus Encephalitis

14 July 2018

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MAPK and heat shock protein 27 activation are associated with respiratory syncytial virus induction of human bronchial epithelial monolayer disruption

14 July 2018

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Thrombocytopenia associated with dengue hemorrhagic fever responds to intravenous administration of anti-D (Rh(0)-D) immune globulin

14 July 2018

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Dengue viruses can infect human primary lung epithelia as well as lung carcinoma cells, and can also induce the secretion of IL-6 and RANTES.

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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CD40 ligand enhances dengue viral infection of dendritic cells: a possible mechanism for T cell-mediated immunopathology.

14 July 2018

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Vascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complement

14 July 2018

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Microarray and real-time RT-PCR analyses of a novel set of differentially expressed human genes in ECV304 endothelial-like cells infected with dengue virus type 2.

14 July 2018

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14 July 2018

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Flavivirus Activates Phosphatidylinositol 3-Kinase Signaling To Block Caspase-Dependent Apoptotic Cell Death at the Early Stage of Virus Infection

14 July 2018

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Proinflammatory factors present in sera from patients with acute dengue infection induce activation and apoptosis of human microvascular endothelial cells: possible role of TNF-alpha in endothelial cell damage in dengue

14 July 2018

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Dengue virus-induced apoptosis in hepatic cells is partly mediated by Apo2 ligand/tumour necrosis factor-related apoptosis-inducing ligand.

14 July 2018

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Replication of varicella-zoster virus is influenced by the levels of JNK/SAPK and p38/MAPK activation

14 July 2018

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Phosphorylation by MAPK regulates simian immunodeficiency virus Vpx protein nuclear import and virus infectivity

14 July 2018

1 reference

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Histopathological aspects of Dengue-2 virus infected mice tissues and complementary virus isolation.

14 July 2018

1 reference

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Aminotransferase changes and acute hepatitis in patients with dengue fever: analysis of 1,585 cases

14 July 2018

1 reference

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TNF-alpha-308A allele, a possible severity risk factor of hemorrhagic manifestation in dengue fever patients

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Lymphocyte activation and hepatic cellular infiltration in immunocompetent mice infected by dengue virus

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Can hematocrit and platelet determination on admission predict shock in hospitalized children with dengue hemorrhagic fever? A clinical observation from a small outbreak

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Apoptosis in dengue virus infected liver cell lines HepG2 and Hep3B.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Clinical presentations of dengue hemorrhagic fever in infants compared to children

14 July 2018

1 reference

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Phosphorylation of initiation factor 4E is resistant to SB203580 in cells expressing a drug-resistant mutant of stress-activated protein kinase 2a/p38.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Anti-TNF antibody treatment reduces mortality in experimental dengue virus infection

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

P38 mitogen-activated protein kinase inhibitor SB203580 has a bi-directional effect on iNOS expression and NO production

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Structure and properties of small heat shock proteins (sHsp) and their interaction with cytoskeleton proteins

14 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

14 July 2018

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0149486

Inflammatory mediators in dengue virus infection in children: interleukin-6 and its relation to C-reactive protein and secretory phospholipase A2.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Decreased immediate inflammatory gene induction in activating transcription factor-2 mutant mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Serine/threonine protein kinases and apoptosis.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Hepatic dysfunction in childhood dengue infection

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogen-activated protein kinase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Elevated plasma interleukin-10 levels in acute dengue correlate with disease severity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Increased pro-inflammatory cytokines (TNF-alpha and IL-6) and anti-inflammatory compounds (sTNFRp55 and sTNFRp75) in Brazilian patients during exanthematic dengue fever

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

The micro-focus reduction neutralization test for determining dengue and Japanese encephalitis neutralizing antibodies in volunteers vaccinated against dengue

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

The impact of dengue haemorrhagic fever on liver function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Cloning and characterization of MEK6, a novel member of the mitogen-activated protein kinase kinase cascade

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Serum levels of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and interleukin-1 beta (IL-1 beta) in dengue-infected patients.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Liver biochemical tests and dengue fever

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Elevated serum gamma-glutamyl-transferase (transpeptidase) and histological liver damage in alcoholism

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Activation of p38 MAPK by feline infectious peritonitis virus regulates pro-inflammatory cytokine production in primary blood-derived feline mononuclear cells

14 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0149486

Γ-glutamyl transferase as an early and sensitive marker in ethanol-induced liver injury of rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0149486

Anti-CD40 conditioning enhances the T(CD8) response to a highly tolerogenic epitope and subsequent immunotherapy of simian virus 40 T antigen-induced pancreatic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0149486

Protective effect of Berberine pretreatment in hepatic ischemia/reperfusion injury of rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0149486

Appetizing rancidity of apoptotic cells for macrophages: oxidation, externalization, and recognition of phosphatidylserine

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0149486

Dengue vascular permeability syndrome: what, no T cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0149486

Mechanism of cell death in acute-on-chronic liver failure: a clinico-pathologic-biomarker study.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Protective effects of the p38 MAPK inhibitor SB203580 on NMDA‑induced injury in primary cerebral cortical neurons.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Modification of the cytoprotective protein C pathway during Dengue virus infection of human endothelial vascular cells.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4764010

Crosstalk between coagulation and inflammation during Dengue virus infection

31 October 2018

1 reference

12 December 2020

p38 MAP kinase-mediated negative inotropic effect of HIV gp120 on cardiac myocytes

1 reference

12 December 2020

SB203580, a p38 mitogen-activated protein kinase inhibitor, fails to improve functional outcome following a moderate spinal cord injury in rat

1 reference

12 December 2020

Apoptosis, vascular leakage and increased risk of severe dengue in a type 2 diabetes mellitus patient

1 reference

12 December 2020

Tumour necrosis factor alpha (TNF- ) stimulation of cells with established dengue virus type 2 infection induces cell death that is accompanied by a reduced ability of TNF- to activate nuclear factor B and reduced sphingosine kinase-1 activity

1 reference

12 December 2020

A novel in situ model of liver cold ischemia–reperfusion in rats

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0149486

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26901653%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26901653%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26901653%20AND%20SRC:MED&resulttype=core&format=json