AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination (Q33563951)

28 July 2017

title

AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination (English)

1 reference

28 July 2017

14

Tasuku Honjo

1 reference

28 July 2017

Il-mi Okazaki

10

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Masamichi Muramatsu

12

object named as

Masamichi Muramatsu

1 reference

28 July 2017

Maki Kobayashi

1

1 reference

28 July 2017

Masatoshi Aida

2

1 reference

28 July 2017

Hitoshi Nagaoka

3

1 reference

28 July 2017

Nasim A Begum

4

1 reference

28 July 2017

Yoko Kitawaki

5

1 reference

28 July 2017

Mikiyo Nakata

6

1 reference

28 July 2017

Andre Stanlie

7

1 reference

28 July 2017

Tomomitsu Doi

8

1 reference

28 July 2017

Lucia Kato

9

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28 July 2017

Reiko Shinkura

11

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28 July 2017

Kazuo Kinoshita

13

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28 July 2017

language of work or name

English

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publication date

11 December 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

published in

1 reference

28 July 2017

volume

106

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28 July 2017

issue

52

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28 July 2017

page(s)

22375-22380

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The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Cdc2-like kinases and DNA topoisomerase I regulate alternative splicing of tissue factor in human endothelial cells

21 June 2018

1 reference

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Conformational variants of duplex DNA correlated with cytosine-rich chromosomal fragile sites.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Mechanism and regulation of class switch recombination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Mechanism of R-loop formation at immunoglobulin class switch sequences

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Sequence dependence of chromosomal R-loops at the immunoglobulin heavy-chain Smu class switch region

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Non-B DNA conformations, mutagenesis and disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Topoisomerase I inhibitors: camptothecins and beyond

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Evidence for a triplex DNA conformation at the bcl-2 major breakpoint region of the t(14;18) translocation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Distinct effects of topoisomerase I and RNA polymerase I inhibitors suggest a dual mechanism of nucleolar/nucleoplasmic partitioning of topoisomerase I.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Variable deletion and duplication at recombination junction ends: implication for staggered double-strand cleavage in class-switch recombination

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

A hallmark of active class switch recombination: transcripts directed by I promoters on looped-out circular DNAs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Directed evolution to increase camptothecin sensitivity of human DNA topoisomerase I.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Interaction of human DNA topoisomerase I with G-quartet structures

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Binding characteristics of Ustilago maydis topoisomerase I to DNA containing secondary structures

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Eukaryotic type I topoisomerase is enriched in the nucleolus and catalytically active on ribosomal DNA.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

Quantitation of immunoglobulin mu-gamma 1 heavy chain switch region recombination by a digestion-circularization polymerase chain reaction method

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2799691

A structural model for the ternary cleavable complex formed between human topoisomerase I, DNA, and camptothecin

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0911879106

Constitutive expression of AID leads to tumorigenesis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0911879106

Two levels of protection for the B cell genome during somatic hypermutation.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0911879106

Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20018730

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Non-B right-handed DNA conformations of homopurine.homopyrimidine sequences in the murine immunoglobulin C alpha switch region

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20018730

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0911879106

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference