Development of neuropeptide drugs that cross the blood-brain barrier (Q33569277)

28 July 2017

1 reference

title

Development of neuropeptide drugs that cross the blood-brain barrier (English)

1 reference

28 July 2017

1 reference

Richard D Egleton

1

1 reference

PubMed ID

15717056

28 July 2017

Thomas P Davis

series ordinal

2

1 reference

28 July 2017

1 January 2005

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28 July 2017

1 reference

28 July 2017

2

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28 July 2017

1

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28 July 2017

44-53

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Brain metastases in melanoma: roles of neurotrophins

28 July 2017

1 reference

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Epilepsy, CNS viral injury and dynorphin

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1 reference

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21 June 2018

1 reference

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Substance P: structure, function, and therapeutics

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New trends in the development of opioid peptide analogues as advanced remedies for pain relief

21 June 2018

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21 June 2018

1 reference

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21 June 2018

1 reference

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Stress responsive neurohormones in depression and anxiety

21 June 2018

1 reference

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Neurotrophin secretory pathways and synaptic plasticity

21 June 2018

1 reference

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On the Role of Somatostatin in Seizure Control: Clues from the Hippocampus

21 June 2018

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Glycopeptide-Membrane Interactions: Glycosyl Enkephalin Analogues Adopt Turn Conformations by NMR and CD in Amphipathic Media

21 June 2018

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Brain-derived neurotrophic factor, behavior, and new directions for the treatment of mental disorders

21 June 2018

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Enhancement of therapeutic protein in vivo activities through glycoengineering

21 June 2018

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Localisation of breast cancer resistance protein in microvessel endothelium of human brain

21 June 2018

1 reference

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A new multidrug resistance protein at the blood-brain barrier

21 June 2018

1 reference

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Crystal structure of biphalin sulfate: a multireceptor opioid peptide.

21 June 2018

1 reference

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Clinical potentials of neuropeptide Y family of hormones

21 June 2018

1 reference

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Functional relevance of carnitine transporter OCTN2 to brain distribution of L-carnitine and acetyl-L-carnitine across the blood-brain barrier

21 June 2018

1 reference

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Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier

21 June 2018

1 reference

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Brain-specific expression of an exogenous gene after i.v. administration

21 June 2018

1 reference

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Neuroprotection in transient focal brain ischemia after delayed intravenous administration of brain-derived neurotrophic factor conjugated to a blood-brain barrier drug targeting system

21 June 2018

1 reference

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Delivery of peptides and proteins through the blood-brain barrier

21 June 2018

1 reference

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Transport of opioids from the brain to the periphery by P-glycoprotein: peripheral actions of central drugs

21 June 2018

1 reference

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Controlled-release, pegylation, liposomal formulations: new mechanisms in the delivery of injectable drugs

21 June 2018

1 reference

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Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability

21 June 2018

1 reference

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Assessment of stereoselectivity of trimethylphenylalanine analogues of delta-opioid [D-Pen(2),D-Pen(5)]-enkephalin.

21 June 2018

1 reference

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Noninvasive gene targeting to the brain

21 June 2018

1 reference

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Improved glycaemic control in obese diabetic ob/ob mice using N-terminally modified gastric inhibitory polypeptide

21 June 2018

1 reference

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Implications of species difference for clinical investigation: studies on the renin-angiotensin system

21 June 2018

1 reference

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Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain

21 June 2018

1 reference

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Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain

21 June 2018

1 reference

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NH2-terminally modified gastric inhibitory polypeptide exhibits amino-peptidase resistance and enhanced antihyperglycemic activity.

21 June 2018

1 reference

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Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier

21 June 2018

1 reference

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Neuroprotection with noninvasive neurotrophin delivery to the brain

21 June 2018

1 reference

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Glycodermorphins: opioid peptides with potent and prolonged analgesic activity and enhanced blood-brain barrier penetration

21 June 2018

1 reference

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Multidrug resistance-related transport proteins in isolated human brain microvessels and in cells cultured from these isolates.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Octanol-water partition of nonzwitterionic peptides: predictive power of a molecular size-based model

21 June 2018

1 reference

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Alkaline phosphatase expression in cultured endothelial cells of aorta and brain microvessels: induction by interleukin-6-type cytokines and suppression by transforming growth factor betas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Extensive biliary excretion of the model opioid peptide [D-PEN2,5] enkephalin in rats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

The entry of [D-penicillamine2,5]enkephalin into the central nervous system: saturation kinetics and specificity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Structure-internalization relationship for adsorptive-mediated endocytosis of basic peptides at the blood-brain barrier

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Localization of purine metabolizing enzymes in bovine brain microvessel endothelial cells: an enzymatic blood-brain barrier for dideoxynucleosides?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Central nervous system pharmacologic effect in conscious rats after intravenous injection of a biotinylated vasoactive intestinal peptide analog coupled to a blood-brain barrier drug delivery system.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Blood-brain barrier penetration and in vivo activity of an NGF conjugate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Pharmacologic effects in vivo in brain by vector-mediated peptide drug delivery.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Protein glycosylation. Structural and functional aspects

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Time course, localization and pharmacological modulation of immediate early inducible genes, brain-derived neurotrophic factor and trkB messenger RNAs in the rat brain following photochemical stroke.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Transport of human recombinant brain-derived neurotrophic factor (BDNF) through the rat blood-brain barrier in vivo using vector-mediated peptide drug delivery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Glycopeptide enkephalin analogues produce analgesia in mice: evidence for penetration of the blood-brain barrier.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Glycation increases the permeability of proteins across the blood-nerve and blood-brain barriers.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Hydrogen bonding potential as a determinant of the in vitro and in situ blood-brain barrier permeability of peptides

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Biologically stable analogues of TRH with increased neuropharmacological potency

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Bis-penicillamine enkephalins possess highly improved specificity toward delta opioid receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Fine structural localization of a blood-brain barrier to exogenous peroxidase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

The localization of monoaminergic blood-brain barrier mechanisms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Junctions between intimately apposed cell membranes in the vertebrate brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Gamma-glutamyl transpeptidase in brain capillaries: possible site of a blood-brain barrier for amino acids

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Astrocyte-mediated induction of tight junctions in brain capillary endothelium: an efficient in vitro model.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Transport of leucine-enkephalin across the blood-brain barrier in the perfused guinea pig brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Blood-brain barrier transcytosis of insulin in developing rabbits

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Absorptive-mediated endocytosis of cationized albumin and a beta-endorphin-cationized albumin chimeric peptide by isolated brain capillaries. Model system of blood-brain barrier transport.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Angiotensin metabolism by cerebral microvascular aminopeptidase A.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Major localization of aminopeptidase M in rat brain microvessels.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Metabolism of opioid peptides by cerebral microvascular aminopeptidase M.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Conformation and orientation of regulatory peptides on lipid membranes. Key to the molecular mechanism of receptor selection.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Kinetic analysis of leucine-enkephalin cellular uptake at the luminal side of the blood-brain barrier of an in situ perfused guinea-pig brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Peptides and the blood-brain barrier: lipophilicity as a predictor of permeability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Kinetics of arginine-vasopressin uptake at the blood-brain barrier

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Distribution of cytochrome P450 activities towards alkoxyresorufin derivatives in rat brain regions, subcellular fractions and isolated cerebral microvessels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Angiotensin peptide regulation of fluid-phase endocytosis in brain microvessel endothelial cell monolayers.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

An inhibitor of endopeptidase-24.15 blocks the degradation of intraventricularly administered dynorphins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Selective transport of an anti-transferrin receptor antibody through the blood-brain barrier in vivo.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Regulation of binding proteins for insulin-like growth factors (IGF) in humans. Increased expression of IGF binding protein 2 during IGF I treatment of healthy adults and in patients with extrapancreatic tumor hypoglycemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Recognition of insulin-like-growth-factor-binding proteins in serum and amniotic fluid by an antiserum against a low-molecular-mass insulin-like-growth-factor-inhibitor/binding protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Increased permeability across the blood-nerve barrier of albumin glycated in vitro and in vivo from patients with diabetic polyneuropathy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Whole body and brain distribution of [3H]cyclic [D-Pen2,D-Pen5] enkephalin after intraperitoneal, intravenous, oral and subcutaneous administration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

The uses and properties of PEG-linked proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

The development of ion regulation at the blood-brain barrier

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Systemic analgesic activity and delta-opioid selectivity in [2,6-dimethyl-Tyr1,D-Pen2,D-Pen5]enkephalin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Amino acid assignment to one of three blood-brain barrier amino acid carriers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Synthetic amino acids and the nature of L-DOPA transport at the blood-brain barrier

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

3-0-Methyldopa uptake and inhibition of L-dopa at the blood-brain barrier

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Rat brain regional uptake and decarboxylation of L-DOPA following carotid injection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Extremely rapid degradation of [3H] methionine-enkephalin by various rat tissues in vivo and in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Peptidyl dipeptidase in rabbit brain microvessels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

A comparison of blood-brain barrier and blood-nerve barrier endothelial cell markers.

21 June 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Transferrin receptor on endothelium of brain capillaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Endogenous peptide Tyr-Pro-Trp-Gly-NH2 (Tyr-W-MIF-1) is transported from the brain to the blood by peptide transport system-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

The effect of conformation of the acyloxyalkoxy-based cyclic prodrugs of opioid peptides on their membrane permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Cyclic penicillamine containing enkephalin analogs display profound delta receptor selectivities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Variable modulation of opioid brain uptake by P-glycoprotein in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Pharmacokinetics and brain uptake of biotinylated basic fibroblast growth factor conjugated to a blood-brain barrier drug delivery system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Antinociceptive activity of liposome-entrapped calcitonin by systemic administration in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Receptor-mediated gene targeting to tissues in vivo following intravenous administration of pegylated immunoliposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Retention of biologic activity of human epidermal growth factor following conjugation to a blood-brain barrier drug delivery vector via an extended poly(ethylene glycol) linker

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Ischemic brain damage in mice after selectively modifying BDNF or NT4 gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Conjugation of brain-derived neurotrophic factor to a blood-brain barrier drug targeting system enables neuroprotection in regional brain ischemia following intravenous injection of the neurotrophin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Enhanced neuroprotective effects of basic fibroblast growth factor in regional brain ischemia after conjugation to a blood-brain barrier delivery vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Rate of 59Fe uptake into brain and cerebrospinal fluid and the influence thereon of antibodies against the transferrin receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Antinociceptive structure-activity studies with enkephalin-based opioid glycopeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Improved bioavailability to the brain of glycosylated Met-enkephalin analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Functional development of neurokinin peptides substance P and neurokinin A in nociception.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Treatment with the CRH1-receptor-antagonist R121919 improves sleep-EEG in patients with depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Morphine formation from codeine in rat brain: a possible mechanism of codeine analgesia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

CYP1A1 and CYP1B1 in blood-brain interfaces: CYP1A1-dependent bioactivation of 7,12-dimethylbenz(a)anthracene in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Localization of immunoreactive glutamyl aminopeptidase in rat brain. I. Association with cerebral microvessels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Enzymatic barrier protects brain capillaries from leukotriene C4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Improved blood-brain barrier penetration and enhanced analgesia of an opioid peptide by glycosylation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Pharmacodynamic and pharmacokinetic characterization of poly(ethylene glycol) conjugation to met-enkephalin analog [D-Pen2, D-Pen5]-enkephalin (DPDPE).

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Organic anion-transporting polypeptides mediate transport of opioid peptides across blood-brain barrier

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Specific renal delivery of sugar-modified low-molecular-weight peptides.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Altered disposition and antinociception of [D-penicillamine(2,5)] enkephalin in mdr1a-gene-deficient mice.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Octanol-water partition: searching for predictive models.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Post-occlusion treatment with BDNF reduces infarct size in a model of permanent occlusion of the middle cerebral artery in rat.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Brain and spinal cord distribution of biphalin: correlation with opioid receptor density and mechanism of CNS entry.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Blood-brain barrier permeability and bioavailability of a highly potent and mu-selective opioid receptor antagonist, CTAP: comparison with morphine

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Passage of a delta-opioid receptor selective enkephalin, [D-penicillamine2,5] enkephalin, across the blood-brain and the blood-cerebrospinal fluid barriers

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Assessment of an in vitro blood-brain barrier model using several [Met5]enkephalin opioid analogs

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=539319

Complete Inactivation of Target mRNA by Biotinylated Antisense Oligodeoxynucleotide-Avidin Conjugates

31 October 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Drug metabolizing enzymes in the brain and cerebral microvessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1602%2FNEURORX.2.1.44

Diminished nociceptive response in mice following immunization with neurokinins

21 January 2018

1 reference

12 December 2020

Fluid-phase endocytosis by primary cultures of bovine brain microvessel endothelial cell monolayers

1 reference

12 December 2020

Effect of peptidases at the blood brain barrier on the permeability of enkephalin

1 reference

12 December 2020

Passage of peptides through the blood-brain barrier with colloidal polymer particles (nanoparticles)

1 reference

12 December 2020

Enkephalin analog prodrugs: assessment of in vitro conversion, enzyme cleavage characterization and blood-brain barrier permeability

1 reference

12 December 2020

Pharmacokinetics of novel erythropoiesis stimulating protein compared with epoetin alfa in dialysis patients

1 reference

12 December 2020

Renal targeting of arginine-vasopressin by modification with carbohydrates at the tyrosine side chain

1 reference

12 December 2020

The effect of halogenation on blood-brain barrier permeability of a novel peptide drug

1 reference

12 December 2020

Reninlike enzymatic activity in the cerebral microvessels of the rat

1 reference

12 December 2020

Met-enkephalin-Arg6-Phe7 metabolism: conversion to Met-enkephalin by brain and kidney dipeptidyl carboxypeptidases

1 reference

12 December 2020

High‐ and Low‐Affinity Transport of D‐Glucose from Blood to Brain

1 reference

12 December 2020

Purification and partial characterization of aminopeptidase A from the serum of pregnant and non-pregnant women

1 reference

12 December 2020

Serum interspecies differences in metabolic pathways of bradykinin and [des-Arg9]BK: influence of enalaprilat

1 reference

12 December 2020

HIV-1 protein gp120 crosses the blood-brain barrier: role of adsorptive endocytosis

1 reference

12 December 2020

N-terminally modified glucagon-like peptide-1(7-36) amide exhibits resistance to enzymatic degradation while maintaining its antihyperglycaemic activity in vivo

1 reference

12 December 2020

Butyrylcholinesterase in pericytes associated with canine brain capillaries

1 reference

12 December 2020

SDZ CO 611: a highly potent glycated analog of somatostatin with improved oral activity

1 reference

12 December 2020

Renal drug targeting using a vector "alkylglycoside"

1 reference

12 December 2020

In vivo metabolism of a new anticancer agent, 6-N-formylamino-12, 13-dihydro-1,11-dihydroxy-13-(beta-D-glucopyranosil)5H-indolo [2,3-a]pyrrolo [3,4-c]carbazole-5,7(6H)-dione (NB-506) in rats and dogs: pharmacokinetics, isolation, identification, and

1 reference

12 December 2020

Neuroprotection mediated via neurotrophic factors and induction of neurotrophic factors

1 reference

12 December 2020

Lipo alpha-amino-beta-hydroxy acids and O-linked glycosides: building blocks for ceramyl and glycosphingoyl peptides

1 reference

12 December 2020

The hydrolysis of endothelins by neutral endopeptidase 24.11 (enkephalinase)

1 reference

12 December 2020

Identifiers

DOI

10.1602/NEURORX.2.1.44

1 reference

28 July 2017

1 reference

28 July 2017

1 reference

PubMed ID

15717056