Aurora kinase inhibition induces PUMA via NF-κB to kill colon cancer cells (Q33579079)

24563542

28 July 2017

title

Aurora kinase inhibition induces PUMA via NF-κB to kill colon cancer cells (English)

1 reference

28 July 2017

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5

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7 June 2020

Jian Yu

7

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7 June 2020

Lin Zhang

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7 June 2020

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Dongshi Chen

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7 June 2020

author name string

Jing Sun

1

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7 June 2020

Kyle Knickelbein

2

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7 June 2020

Kan He

3

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7 June 2020

Yongqian Shu

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7 June 2020

publication date

21 February 2014

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24563542

Molecular Cancer Therapeutics

28 July 2017

published in

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7 June 2020

volume

13

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7 June 2020

issue

5

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7 June 2020

page(s)

1298-1308

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Intestinal stem cell injury and protection during cancer therapy

7 June 2020

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21 June 2018

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Killing cells by targeting mitosis

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Shared and separate functions of polo-like kinases and aurora kinases in cancer

21 June 2018

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Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis

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PUMA induction by FoxO3a mediates the anticancer activities of the broad-range kinase inhibitor UCN-01.

21 June 2018

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21 June 2018

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Bcl-XL represents a druggable molecular vulnerability during aurora B inhibitor-mediated polyploidization

21 June 2018

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Phase I dose escalation study of MK-0457, a novel Aurora kinase inhibitor, in adult patients with advanced solid tumors

21 June 2018

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Aurora kinase inhibitors--rising stars in cancer therapeutics?

21 June 2018

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Growth factors protect intestinal stem cells from radiation-induced apoptosis by suppressing PUMA through the PI3K/AKT/p53 axis.

21 June 2018

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Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways

21 June 2018

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PUMA, a potent killer with or without p53

21 June 2018

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How do anti-mitotic drugs kill cancer cells?

21 June 2018

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PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis

21 June 2018

1 reference

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PUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cells

21 June 2018

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21 June 2018

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Aurora kinase A inhibition leads to p73-dependent apoptosis in p53-deficient cancer cells

21 June 2018

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Sp1 and p73 activate PUMA following serum starvation

21 June 2018

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Molecular basis of drug resistance in aurora kinases

21 June 2018

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21 June 2018

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SMAC/Diablo mediates the proapoptotic function of PUMA by regulating PUMA-induced mitochondrial events

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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PUMA Dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24563542

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12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1535-7163.MCT-13-0846

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7 June 2020

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7 June 2020

24563542

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